ID   RT106_MAGO7             Reviewed;         468 AA.
AC   A4R6X5; G4NAI1;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Histone chaperone RTT106;
GN   Name=RTT106; ORFNames=MGG_09713;
OS   Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast
OS   fungus) (Pyricularia oryzae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Magnaporthales; Pyriculariaceae; Pyricularia.
OX   NCBI_TaxID=242507;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=70-15 / ATCC MYA-4617 / FGSC 8958;
RX   PubMed=15846337; DOI=10.1038/nature03449;
RA   Dean R.A., Talbot N.J., Ebbole D.J., Farman M.L., Mitchell T.K.,
RA   Orbach M.J., Thon M.R., Kulkarni R., Xu J.-R., Pan H., Read N.D.,
RA   Lee Y.-H., Carbone I., Brown D., Oh Y.Y., Donofrio N., Jeong J.S.,
RA   Soanes D.M., Djonovic S., Kolomiets E., Rehmeyer C., Li W., Harding M.,
RA   Kim S., Lebrun M.-H., Bohnert H., Coughlan S., Butler J., Calvo S.E.,
RA   Ma L.-J., Nicol R., Purcell S., Nusbaum C., Galagan J.E., Birren B.W.;
RT   "The genome sequence of the rice blast fungus Magnaporthe grisea.";
RL   Nature 434:980-986(2005).
CC   -!- FUNCTION: Histones H3 and H4 chaperone involved in the nucleosome
CC       formation and heterochromatin silencing. Required for the deposition of
CC       H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role
CC       in the transcriptional regulation of the cell-cycle dependent histone
CC       genes by creating a repressive structure at the core histone gene
CC       promoter (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with histones H3 and H4. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Chromosome {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RTT106 family. {ECO:0000305}.
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DR   EMBL; CM001234; EHA51319.1; -; Genomic_DNA.
DR   RefSeq; XP_003717638.1; XM_003717590.1.
DR   AlphaFoldDB; A4R6X5; -.
DR   SMR; A4R6X5; -.
DR   STRING; 318829.MGG_17277T0; -.
DR   EnsemblFungi; MGG_17277T0; MGG_17277T0; MGG_17277.
DR   GeneID; 12986586; -.
DR   KEGG; mgr:MGG_17277; -.
DR   VEuPathDB; FungiDB:MGG_17277; -.
DR   eggNOG; ENOG502R9PE; Eukaryota.
DR   HOGENOM; CLU_033828_0_0_1; -.
DR   InParanoid; A4R6X5; -.
DR   OMA; AMPEAHR; -.
DR   Proteomes; UP000009058; Chromosome 4.
DR   GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   Gene3D; 2.30.29.30; -; 1.
DR   InterPro; IPR013719; DUF1747.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   Pfam; PF08512; Rtt106; 1.
DR   SMART; SM01287; Rtt106; 1.
PE   3: Inferred from homology;
KW   Chaperone; Chromosome; DNA-binding; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..468
FT                   /note="Histone chaperone RTT106"
FT                   /id="PRO_0000320495"
FT   REGION          55..82
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          365..468
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        66..82
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        365..379
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        415..468
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   468 AA;  51037 MW;  D7593453E865824E CRC64;
     MSQLDTEKLG LVFQSRPDIL NGIKEAADSP ARVDLFNNIA AFVLEQLTAD AADQPVSKRR
     RVDVDQTNGT PNGNAKTEGT SSTDVVAEAA AEELQLEIKD ISVSIPQRKK YNLCLTKHFI
     FARTNADPKP VAGMVWRWED IEHVFFLPVP EKTQQQFNYV FLPRGTYLPA SNNQSTTGAK
     PQQPSTSAAA EPLLFTIPQA APKPGSLAGK VAAQAQVAAD SYSSLVNWAV PQFLRAAATR
     LGLSSPVEIV ASDPKQFASA VRQSHRPSEK AVHVKAFRGS KDGYLFFLRT GILWGFKKPL
     VFLPLDRIVS VSYTSVLQRT FNMVVEVDVG DGATEELEFS MLDQEDYGGI NQDYVHKYNL
     QDRSMAEQRK AKRELAENAK KGGAGAAAGE DGENAADDGD TNMGELQKAE MEEEQRLQDE
     EDEDEEDYDP GSDGDSEGEG TSSEEEDGDG DGGGDDDDDD DDEGEDDL