RT11_ARATH
ID RT11_ARATH Reviewed; 314 AA.
AC Q8VZT8; Q9C6S3;
DT 04-FEB-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 121.
DE RecName: Full=Probable ribosomal protein S11, mitochondrial {ECO:0000305};
DE Short=MRP-S11;
DE Short=S11mt;
DE AltName: Full=Protein NUCLEAR FUSION DEFECTIVE 3, mitochondrial {ECO:0000303|PubMed:16698901};
DE Flags: Precursor;
GN Name=NFD3 {ECO:0000312|EMBL:AEE31398.1};
GN OrderedLocusNames=At1g31817 {ECO:0000312|Araport:AT1G31817};
GN ORFNames=F5M6.25 {ECO:0000312|EMBL:AAG50732.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|EMBL:AAL36201.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RC STRAIN=cv. Columbia;
RX PubMed=16698901; DOI=10.1104/pp.106.079319;
RA Portereiko M.F., Sandaklie-Nikolova L., Lloyd A., Dever C.A., Otsuga D.,
RA Drews G.N.;
RT "NUCLEAR FUSION DEFECTIVE1 encodes the Arabidopsis RPL21M protein and is
RT required for karyogamy during female gametophyte development and
RT fertilization.";
RL Plant Physiol. 141:957-965(2006).
CC -!- FUNCTION: Required for karyogamy during female gametophyte development,
CC when the two polar nuclei fuse to form the diploid central cell
CC nucleus. {ECO:0000269|PubMed:16698901}.
CC -!- SUBUNIT: Component of the mitochondrial ribosome small subunit (28S)
CC which comprises a 12S rRNA and about 30 distinct proteins.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000255}.
CC -!- DISRUPTION PHENOTYPE: Failure of fusion of the polar nuclei during
CC megagametogenesis. {ECO:0000269|PubMed:16698901}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS11 family.
CC {ECO:0000255|HAMAP-Rule:MF_01310}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG50732.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC079041; AAG50732.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE31398.1; -; Genomic_DNA.
DR EMBL; AY063845; AAL36201.1; -; mRNA.
DR EMBL; AY117289; AAM51364.1; -; mRNA.
DR PIR; B86442; B86442.
DR RefSeq; NP_564385.1; NM_102918.3.
DR PDB; 6XYW; EM; 3.86 A; Bj=1-314.
DR PDBsum; 6XYW; -.
DR AlphaFoldDB; Q8VZT8; -.
DR SMR; Q8VZT8; -.
DR IntAct; Q8VZT8; 3.
DR STRING; 3702.AT1G31817.1; -.
DR PaxDb; Q8VZT8; -.
DR PRIDE; Q8VZT8; -.
DR ProteomicsDB; 226632; -.
DR EnsemblPlants; AT1G31817.1; AT1G31817.1; AT1G31817.
DR GeneID; 840071; -.
DR Gramene; AT1G31817.1; AT1G31817.1; AT1G31817.
DR KEGG; ath:AT1G31817; -.
DR Araport; AT1G31817; -.
DR TAIR; locus:2826195; AT1G31817.
DR eggNOG; ENOG502RZ9G; Eukaryota.
DR HOGENOM; CLU_892389_0_0_1; -.
DR InParanoid; Q8VZT8; -.
DR OMA; GQMNQEG; -.
DR OrthoDB; 1303296at2759; -.
DR PhylomeDB; Q8VZT8; -.
DR PRO; PR:Q8VZT8; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q8VZT8; baseline and differential.
DR Genevisible; Q8VZT8; AT.
DR GO; GO:0005763; C:mitochondrial small ribosomal subunit; IBA:GO_Central.
DR GO; GO:0048027; F:mRNA 5'-UTR binding; IBA:GO_Central.
DR GO; GO:0070181; F:small ribosomal subunit rRNA binding; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0000741; P:karyogamy; IMP:UniProtKB.
DR GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR GO; GO:0010197; P:polar nucleus fusion; IMP:UniProtKB.
DR GO; GO:0000028; P:ribosomal small subunit assembly; IBA:GO_Central.
DR GO; GO:0006412; P:translation; IBA:GO_Central.
DR Gene3D; 3.30.420.80; -; 1.
DR HAMAP; MF_01310; Ribosomal_S11; 1.
DR InterPro; IPR001971; Ribosomal_S11.
DR InterPro; IPR036967; Ribosomal_S11_sf.
DR PANTHER; PTHR11759; PTHR11759; 1.
DR Pfam; PF00411; Ribosomal_S11; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Developmental protein; Karyogamy; Mitochondrion;
KW Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding;
KW rRNA-binding; Transit peptide.
FT TRANSIT 1..37
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 38..314
FT /note="Probable ribosomal protein S11, mitochondrial"
FT /id="PRO_0000431842"
FT REGION 34..138
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..73
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 96..138
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 314 AA; 33926 MW; CD34AADA0533D8F6 CRC64;
MNGVSRHLRA SSLLSLIRSY GGINSVCRFS SQSDGFSGGR FREQVPVSGE SANNSGLSNT
GRIGSSPEPN PSTLRTFGDM KAGLLNRGVN GFSAPNAPPT FKSSLRSRLP NSLPDQFGQT
NPGLPNTGGS GFSAPSLSSY ENFTQSSSLL KENSRSGGKS SDLDFVREVI EDEGRRTAGI
FSHFQRPNLE TNADIIHIKM LRNNTFVTVT DSKGNVKCKA TSGSLPDLKG GRKMTNYTAD
ATAENIGRRA KAMGLKSVVV KVNGFTHFGK KKKAIIAFRD GFTNSRSDQN PIVYIEDTTR
KAHNGCRLPR KRRV
