RT12_BOVIN
ID RT12_BOVIN Reviewed; 139 AA.
AC Q29RU1;
DT 13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 04-APR-2006, sequence version 1.
DT 03-AUG-2022, entry version 95.
DE RecName: Full=28S ribosomal protein S12, mitochondrial;
DE Short=MRP-S12;
DE Short=S12mt;
DE Flags: Precursor;
GN Name=MRPS12;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Testis;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0007744|PDB:3JD5}
RP STRUCTURE BY ELECTRON MICROSCOPY (7.00 ANGSTROMS), SUBCELLULAR LOCATION,
RP AND SUBUNIT.
RX PubMed=24799711; DOI=10.1073/pnas.1401657111;
RA Kaushal P.S., Sharma M.R., Booth T.M., Haque E.M., Tung C.S.,
RA Sanbonmatsu K.Y., Spremulli L.L., Agrawal R.K.;
RT "Cryo-EM structure of the small subunit of the mammalian mitochondrial
RT ribosome.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:7284-7289(2014).
CC -!- SUBUNIT: Component of the mitochondrial ribosome small subunit (28S)
CC which comprises a 12S rRNA and about 30 distinct proteins.
CC {ECO:0000269|PubMed:24799711}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:24799711}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS12 family.
CC {ECO:0000305}.
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DR EMBL; BC114019; AAI14020.1; -; mRNA.
DR RefSeq; NP_001070569.1; NM_001077101.2.
DR RefSeq; XP_005219097.1; XM_005219040.3.
DR RefSeq; XP_005219098.1; XM_005219041.3.
DR PDB; 3JD5; EM; 7.00 A; L=1-139.
DR PDB; 6NEQ; EM; 3.32 A; L=1-139.
DR PDB; 6NF8; EM; 3.48 A; L=1-139.
DR PDBsum; 3JD5; -.
DR PDBsum; 6NEQ; -.
DR PDBsum; 6NF8; -.
DR AlphaFoldDB; Q29RU1; -.
DR SMR; Q29RU1; -.
DR IntAct; Q29RU1; 1.
DR STRING; 9913.ENSBTAP00000002335; -.
DR PaxDb; Q29RU1; -.
DR PRIDE; Q29RU1; -.
DR Ensembl; ENSBTAT00000002335; ENSBTAP00000002335; ENSBTAG00000001782.
DR GeneID; 768042; -.
DR KEGG; bta:768042; -.
DR CTD; 6183; -.
DR VEuPathDB; HostDB:ENSBTAG00000001782; -.
DR VGNC; VGNC:31656; MRPS12.
DR eggNOG; KOG1750; Eukaryota.
DR GeneTree; ENSGT00550000075103; -.
DR HOGENOM; CLU_104295_3_1_1; -.
DR InParanoid; Q29RU1; -.
DR OMA; ASLAQMH; -.
DR OrthoDB; 1542634at2759; -.
DR TreeFam; TF315095; -.
DR Proteomes; UP000009136; Chromosome 18.
DR Bgee; ENSBTAG00000001782; Expressed in laryngeal cartilage and 108 other tissues.
DR GO; GO:0005743; C:mitochondrial inner membrane; TAS:Reactome.
DR GO; GO:0005763; C:mitochondrial small ribosomal subunit; IDA:UniProtKB.
DR GO; GO:0005840; C:ribosome; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; HDA:UniProtKB.
DR GO; GO:0032543; P:mitochondrial translation; HDA:UniProtKB.
DR GO; GO:0006412; P:translation; IBA:GO_Central.
DR CDD; cd03368; Ribosomal_S12; 1.
DR Gene3D; 2.40.50.140; -; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR006032; Ribosomal_S12/S23.
DR InterPro; IPR005679; Ribosomal_S12_bac.
DR PANTHER; PTHR11652; PTHR11652; 1.
DR Pfam; PF00164; Ribosom_S12_S23; 1.
DR PRINTS; PR01034; RIBOSOMALS12.
DR SUPFAM; SSF50249; SSF50249; 1.
DR TIGRFAMs; TIGR00981; rpsL_bact; 1.
DR PROSITE; PS00055; RIBOSOMAL_S12; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Mitochondrion; Reference proteome; Ribonucleoprotein;
KW Ribosomal protein; Transit peptide.
FT TRANSIT 1..29
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 30..139
FT /note="28S ribosomal protein S12, mitochondrial"
FT /id="PRO_0000240294"
FT REGION 37..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT HELIX 33..39
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 56..68
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 72..74
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 78..83
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 91..94
FT /evidence="ECO:0007829|PDB:6NF8"
FT STRAND 97..99
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 107..112
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 127..129
FT /evidence="ECO:0007829|PDB:6NEQ"
SQ SEQUENCE 139 AA; 15447 MW; CA49B7D27C60EECA CRC64;
MSWSGLLRGL SMSLNYGLAL APRPWGTRPM ATLNQLHRRG PPKFPPSKPG PTEGRPQLKG
VVLRTFIRKP KKPNSANRKC CRVRLSTGRE AVCFIPGEGH NLQEHHVVLV QGGRTQDLPG
VKLKVVRGKY DCGHVQKKK
