RT12_MOUSE
ID RT12_MOUSE Reviewed; 139 AA.
AC O35680;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 160.
DE RecName: Full=28S ribosomal protein S12, mitochondrial;
DE Short=MRP-S12;
DE Short=S12mt;
DE AltName: Full=MT-RPS12;
DE Flags: Precursor;
GN Name=Mrps12; Synonyms=Rpms12;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=C57BL/6J;
RX PubMed=9434165; DOI=10.1016/s0378-1119(97)00521-0;
RA Shah Z.H., O'Dell K.M., Miller S.C.M., An X., Jacobs H.T.;
RT "Metazoan nuclear genes for mitoribosomal protein S12.";
RL Gene 204:55-62(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Czech II, and FVB/N; TISSUE=Colon, and Lung;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBUNIT: Component of the mitochondrial ribosome small subunit (28S)
CC which comprises a 12S rRNA and about 30 distinct proteins.
CC {ECO:0000250|UniProtKB:O15235}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:O15235}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS12 family.
CC {ECO:0000305}.
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DR EMBL; Y11682; CAA72378.1; -; mRNA.
DR EMBL; BC012679; AAH12679.1; -; mRNA.
DR EMBL; BC027522; AAH27522.1; -; mRNA.
DR CCDS; CCDS21052.1; -.
DR RefSeq; NP_036015.1; NM_011885.4.
DR RefSeq; XP_006539971.1; XM_006539908.2.
DR AlphaFoldDB; O35680; -.
DR SMR; O35680; -.
DR BioGRID; 204858; 21.
DR ComplexPortal; CPX-5301; 28S mitochondrial small ribosomal subunit.
DR IntAct; O35680; 1.
DR MINT; O35680; -.
DR STRING; 10090.ENSMUSP00000062066; -.
DR iPTMnet; O35680; -.
DR PhosphoSitePlus; O35680; -.
DR EPD; O35680; -.
DR MaxQB; O35680; -.
DR PaxDb; O35680; -.
DR PeptideAtlas; O35680; -.
DR PRIDE; O35680; -.
DR ProteomicsDB; 256634; -.
DR Antibodypedia; 30241; 187 antibodies from 26 providers.
DR DNASU; 24030; -.
DR Ensembl; ENSMUST00000056078; ENSMUSP00000062066; ENSMUSG00000045948.
DR Ensembl; ENSMUST00000171183; ENSMUSP00000132443; ENSMUSG00000045948.
DR GeneID; 24030; -.
DR KEGG; mmu:24030; -.
DR UCSC; uc009fzo.1; mouse.
DR CTD; 6183; -.
DR MGI; MGI:1346333; Mrps12.
DR VEuPathDB; HostDB:ENSMUSG00000045948; -.
DR eggNOG; KOG1750; Eukaryota.
DR GeneTree; ENSGT00550000075103; -.
DR HOGENOM; CLU_104295_3_1_1; -.
DR InParanoid; O35680; -.
DR OMA; ASLAQMH; -.
DR OrthoDB; 1542634at2759; -.
DR PhylomeDB; O35680; -.
DR TreeFam; TF315095; -.
DR Reactome; R-MMU-5389840; Mitochondrial translation elongation.
DR Reactome; R-MMU-5419276; Mitochondrial translation termination.
DR BioGRID-ORCS; 24030; 22 hits in 73 CRISPR screens.
DR ChiTaRS; Mrps12; mouse.
DR PRO; PR:O35680; -.
DR Proteomes; UP000000589; Chromosome 7.
DR RNAct; O35680; protein.
DR Bgee; ENSMUSG00000045948; Expressed in right kidney and 259 other tissues.
DR ExpressionAtlas; O35680; baseline and differential.
DR Genevisible; O35680; MM.
DR GO; GO:0005743; C:mitochondrial inner membrane; IC:ComplexPortal.
DR GO; GO:0005763; C:mitochondrial small ribosomal subunit; ISS:UniProtKB.
DR GO; GO:0005739; C:mitochondrion; HDA:MGI.
DR GO; GO:0005840; C:ribosome; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; ISS:UniProtKB.
DR GO; GO:0032543; P:mitochondrial translation; ISS:UniProtKB.
DR GO; GO:0006412; P:translation; IBA:GO_Central.
DR CDD; cd03368; Ribosomal_S12; 1.
DR Gene3D; 2.40.50.140; -; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR006032; Ribosomal_S12/S23.
DR InterPro; IPR005679; Ribosomal_S12_bac.
DR PANTHER; PTHR11652; PTHR11652; 1.
DR Pfam; PF00164; Ribosom_S12_S23; 1.
DR PRINTS; PR01034; RIBOSOMALS12.
DR SUPFAM; SSF50249; SSF50249; 1.
DR TIGRFAMs; TIGR00981; rpsL_bact; 1.
DR PROSITE; PS00055; RIBOSOMAL_S12; 1.
PE 2: Evidence at transcript level;
KW Mitochondrion; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW Transit peptide.
FT TRANSIT 1..29
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 30..139
FT /note="28S ribosomal protein S12, mitochondrial"
FT /id="PRO_0000030607"
SQ SEQUENCE 139 AA; 15437 MW; B365FE940025EA08 CRC64;
MSWPGLLYGL TTSLSRGLAL APQLWAARSM ATLNQMHRLG PRKEPPKRLG PTEGRPQLKG
VVLRTFIRKP KKPNSANRKC CRVRLSTGKE AVCFIPGEGH TLQEHHVVLV EGGRTQDLPG
VKLKVVRGKY DCGHVQKKK
