ID   BCN1_LACLL              Reviewed;          29 AA.
AC   P85833;
DT   15-MAR-2017, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2017, sequence version 1.
DT   25-MAY-2022, entry version 4.
DE   RecName: Full=Bacteriocin {ECO:0000303|PubMed:22805947};
OS   Lactococcus lactis subsp. lactis (Streptococcus lactis).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Lactococcus.
OX   NCBI_TaxID=1360 {ECO:0000303|PubMed:22805947};
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, FUNCTION, BIOPHYSICOCHEMICAL PROPERTIES, AND SUBCELLULAR
RP   LOCATION.
RC   STRAIN=LL171 {ECO:0000303|PubMed:22805947};
RX   PubMed=22805947; DOI=10.1007/s11274-011-0971-4;
RA   Kumari A., Akkoc N., Akcelik M.;
RT   "Purification and partial characterization of bacteriocin produced by
RT   Lactococcus lactis ssp. lactis LL171.";
RL   World J. Microbiol. Biotechnol. 28:1647-1655(2012).
CC   -!- FUNCTION: Has antibacterial activity against strains of
CC       L.monocytogenes, L.lactis, B.subtilis, S.typhi, S.aureus,
CC       C.perfringens, E.aerogenes and M.luteus but not against E.coli,
CC       S.sonnei, S.pneumoniae, S.faecalis, P.aeruginosa, K.pneumoniae or
CC       P.vulgaris. {ECO:0000269|PubMed:22805947}.
CC   -!- BIOPHYSICOCHEMICAL PROPERTIES:
CC       pH dependence:
CC         Activity is stable between pH 2 and 9 but decreases at a more basic
CC         pH. {ECO:0000269|PubMed:22805947};
CC       Temperature dependence:
CC         Thermostable. Activity remains unaffected even after incubation at
CC         100 degrees Celsius for 30 minutes. {ECO:0000269|PubMed:22805947};
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:22805947}.
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DR   AlphaFoldDB; P85833; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Antibiotic; Antimicrobial; Bacteriocin; Direct protein sequencing;
KW   Secreted.
FT   PEPTIDE         1..29
FT                   /note="Bacteriocin"
FT                   /evidence="ECO:0000269|PubMed:22805947"
FT                   /id="PRO_0000439206"
SQ   SEQUENCE   29 AA;  3353 MW;  6781F15A2DFDEA58 CRC64;
     KKIDTRTGKT MEKTEKKIEL SLKNMKTAT