RT14_MOUSE
ID RT14_MOUSE Reviewed; 128 AA.
AC Q9CR88; Q3UNI7;
DT 16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 131.
DE RecName: Full=28S ribosomal protein S14, mitochondrial;
DE Short=MRP-S14;
DE Short=S14mt;
GN Name=Mrps14;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Pancreas, Thymus, and Tongue;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=FVB/N-3;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Brain, Brown adipose tissue, Heart, Kidney, Liver, and Testis;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [4]
RP INTERACTION WITH LIAT1.
RX PubMed=25369936; DOI=10.1073/pnas.1419587111;
RA Brower C.S., Rosen C.E., Jones R.H., Wadas B.C., Piatkov K.I.,
RA Varshavsky A.;
RT "Liat1, an arginyltransferase-binding protein whose evolution among
RT primates involved changes in the numbers of its 10-residue repeats.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:E4936-E4945(2014).
CC -!- SUBUNIT: Component of the mitochondrial ribosome small subunit (28S)
CC which comprises a 12S rRNA and about 30 distinct proteins (By
CC similarity). Interacts with LIAT1. {ECO:0000250|UniProtKB:O60783,
CC ECO:0000269|PubMed:25369936}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:O60783}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS14 family.
CC {ECO:0000305}.
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DR EMBL; AK007673; BAB25177.1; -; mRNA.
DR EMBL; AK010242; BAB26793.1; -; mRNA.
DR EMBL; AK083352; BAC38881.1; -; mRNA.
DR EMBL; AK144195; BAE25760.1; -; mRNA.
DR EMBL; BC044057; AAH44057.1; -; mRNA.
DR CCDS; CCDS15405.1; -.
DR RefSeq; NP_079750.1; NM_025474.4.
DR AlphaFoldDB; Q9CR88; -.
DR SMR; Q9CR88; -.
DR ComplexPortal; CPX-5301; 28S mitochondrial small ribosomal subunit.
DR STRING; 10090.ENSMUSP00000120075; -.
DR EPD; Q9CR88; -.
DR MaxQB; Q9CR88; -.
DR PaxDb; Q9CR88; -.
DR PRIDE; Q9CR88; -.
DR ProteomicsDB; 262719; -.
DR Antibodypedia; 63335; 56 antibodies from 14 providers.
DR DNASU; 64659; -.
DR Ensembl; ENSMUST00000135680; ENSMUSP00000120075; ENSMUSG00000058267.
DR GeneID; 64659; -.
DR KEGG; mmu:64659; -.
DR UCSC; uc007def.1; mouse.
DR CTD; 63931; -.
DR MGI; MGI:1928141; Mrps14.
DR VEuPathDB; HostDB:ENSMUSG00000058267; -.
DR eggNOG; KOG1741; Eukaryota.
DR GeneTree; ENSGT00390000015663; -.
DR HOGENOM; CLU_139869_1_0_1; -.
DR InParanoid; Q9CR88; -.
DR OMA; FGLCRNQ; -.
DR OrthoDB; 1612572at2759; -.
DR PhylomeDB; Q9CR88; -.
DR TreeFam; TF320418; -.
DR Reactome; R-MMU-5389840; Mitochondrial translation elongation.
DR Reactome; R-MMU-5419276; Mitochondrial translation termination.
DR BioGRID-ORCS; 64659; 26 hits in 76 CRISPR screens.
DR ChiTaRS; Mrps14; mouse.
DR PRO; PR:Q9CR88; -.
DR Proteomes; UP000000589; Chromosome 1.
DR RNAct; Q9CR88; protein.
DR Bgee; ENSMUSG00000058267; Expressed in facial nucleus and 255 other tissues.
DR ExpressionAtlas; Q9CR88; baseline and differential.
DR Genevisible; Q9CR88; MM.
DR GO; GO:0005743; C:mitochondrial inner membrane; IC:ComplexPortal.
DR GO; GO:0005763; C:mitochondrial small ribosomal subunit; ISS:UniProtKB.
DR GO; GO:0005739; C:mitochondrion; HDA:MGI.
DR GO; GO:0031965; C:nuclear membrane; ISO:MGI.
DR GO; GO:0015935; C:small ribosomal subunit; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; ISS:MGI.
DR GO; GO:0032543; P:mitochondrial translation; ISO:MGI.
DR GO; GO:0006412; P:translation; IBA:GO_Central.
DR InterPro; IPR001209; Ribosomal_S14.
DR PANTHER; PTHR19836; PTHR19836; 1.
DR Pfam; PF00253; Ribosomal_S14; 1.
PE 1: Evidence at protein level;
KW Mitochondrion; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT CHAIN 1..128
FT /note="28S ribosomal protein S14, mitochondrial"
FT /id="PRO_0000131014"
SQ SEQUENCE 128 AA; 14920 MW; 1009BAD5B4F5E65B CRC64;
MAASVLGSLL RTFRQAVPPS ASGQVRGYYV DWRMLRDLKR RKMAYEYADE RLRINSLRKN
TILPKDLQEM AGDEIAALPR DSCPVRIRNR CVMTSRPRGV KRRWRLSRIV FRHLADHGLL
SGVQRAIW
