RT16_BOVIN
ID RT16_BOVIN Reviewed; 135 AA.
AC P82915; Q17QA2;
DT 27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=28S ribosomal protein S16, mitochondrial;
DE Short=MRP-S16;
DE Short=S16mt;
DE Flags: Precursor;
GN Name=MRPS16; Synonyms=RPMS16;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Fetal lung;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP PROTEIN SEQUENCE OF 56-64 AND 114-124, IDENTIFICATION IN THE 28S
RP MITOCHONDRIAL RIBOSOME, SUBCELLULAR LOCATION, AND SUBUNIT.
RC TISSUE=Liver;
RX PubMed=11279123; DOI=10.1074/jbc.m100727200;
RA Koc E.C., Burkhart W., Blackburn K., Moseley A., Spremulli L.L.;
RT "The small subunit of the mammalian mitochondrial ribosome: identification
RT of the full complement of ribosomal proteins present.";
RL J. Biol. Chem. 276:19363-19374(2001).
RN [3] {ECO:0007744|PDB:3JD5}
RP STRUCTURE BY ELECTRON MICROSCOPY (7.00 ANGSTROMS), SUBCELLULAR LOCATION,
RP AND SUBUNIT.
RX PubMed=24799711; DOI=10.1073/pnas.1401657111;
RA Kaushal P.S., Sharma M.R., Booth T.M., Haque E.M., Tung C.S.,
RA Sanbonmatsu K.Y., Spremulli L.L., Agrawal R.K.;
RT "Cryo-EM structure of the small subunit of the mammalian mitochondrial
RT ribosome.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:7284-7289(2014).
CC -!- SUBUNIT: Component of the mitochondrial ribosome small subunit (28S)
CC which comprises a 12S rRNA and about 30 distinct proteins.
CC {ECO:0000269|PubMed:11279123, ECO:0000269|PubMed:24799711}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:11279123,
CC ECO:0000269|PubMed:24799711}.
CC -!- SIMILARITY: Belongs to the bacterial ribosomal protein bS16 family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC118470; AAI18471.1; -; mRNA.
DR RefSeq; NP_001068942.1; NM_001075474.2.
DR PDB; 3JD5; EM; 7.00 A; P=1-135.
DR PDB; 6NEQ; EM; 3.32 A; P=1-135.
DR PDB; 6NF8; EM; 3.48 A; P=1-135.
DR PDBsum; 3JD5; -.
DR PDBsum; 6NEQ; -.
DR PDBsum; 6NF8; -.
DR AlphaFoldDB; P82915; -.
DR SMR; P82915; -.
DR CORUM; P82915; -.
DR IntAct; P82915; 2.
DR STRING; 9913.ENSBTAP00000001255; -.
DR iPTMnet; P82915; -.
DR PaxDb; P82915; -.
DR PRIDE; P82915; -.
DR Ensembl; ENSBTAT00000001255; ENSBTAP00000001255; ENSBTAG00000000950.
DR GeneID; 510899; -.
DR KEGG; bta:510899; -.
DR CTD; 51021; -.
DR VEuPathDB; HostDB:ENSBTAG00000000950; -.
DR VGNC; VGNC:31657; MRPS16.
DR eggNOG; KOG3419; Eukaryota.
DR GeneTree; ENSGT00390000014309; -.
DR HOGENOM; CLU_100590_4_0_1; -.
DR InParanoid; P82915; -.
DR OMA; HMSEPAA; -.
DR OrthoDB; 1630052at2759; -.
DR TreeFam; TF105637; -.
DR Proteomes; UP000009136; Chromosome 28.
DR Bgee; ENSBTAG00000000950; Expressed in oocyte and 106 other tissues.
DR GO; GO:0005743; C:mitochondrial inner membrane; TAS:Reactome.
DR GO; GO:0005763; C:mitochondrial small ribosomal subunit; IDA:UniProtKB.
DR GO; GO:0015935; C:small ribosomal subunit; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; HDA:UniProtKB.
DR GO; GO:0032543; P:mitochondrial translation; HDA:UniProtKB.
DR Gene3D; 3.30.1320.10; -; 1.
DR HAMAP; MF_00385; Ribosomal_S16; 1.
DR InterPro; IPR000307; Ribosomal_S16.
DR InterPro; IPR023803; Ribosomal_S16_dom_sf.
DR PANTHER; PTHR12919; PTHR12919; 1.
DR Pfam; PF00886; Ribosomal_S16; 1.
DR SUPFAM; SSF54565; SSF54565; 1.
DR TIGRFAMs; TIGR00002; S16; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Direct protein sequencing; Mitochondrion; Phosphoprotein;
KW Reference proteome; Ribonucleoprotein; Ribosomal protein; Transit peptide.
FT TRANSIT 1..34
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 35..135
FT /note="28S ribosomal protein S16, mitochondrial"
FT /id="PRO_0000167327"
FT MOD_RES 130
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q9Y3D3"
FT CONFLICT 62..63
FT /note="GE -> AD (in Ref. 2; AA sequence)"
FT /evidence="ECO:0000305"
FT STRAND 17..20
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 34..37
FT /evidence="ECO:0007829|PDB:6NF8"
FT STRAND 38..41
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 43..45
FT /evidence="ECO:0007829|PDB:6NF8"
FT STRAND 48..50
FT /evidence="ECO:0007829|PDB:6NF8"
FT STRAND 52..54
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 62..68
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 70..77
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 85..94
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 95..97
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 101..123
FT /evidence="ECO:0007829|PDB:6NEQ"
SQ SEQUENCE 135 AA; 15132 MW; 96264C9886ED1E6B CRC64;
MVQLTTVLCK AYRGGHLTIR LALGGCTNRP FYRIVAAHNK CPRDGRFVEQ LGSYDPMPNS
HGEKLVALNL DRIRHWIGCG AHLSKPVEKL LGLSGFFPLH PMVITNAERL RRKRAQEVLL
AAQKTDTEAT ETKEN
