RT16_MOUSE
ID RT16_MOUSE Reviewed; 135 AA.
AC Q9CPX7;
DT 27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT 27-APR-2001, sequence version 1.
DT 03-AUG-2022, entry version 149.
DE RecName: Full=28S ribosomal protein S16, mitochondrial;
DE Short=MRP-S16;
DE Short=S16mt;
DE Flags: Precursor;
GN Name=Mrps16; Synonyms=Rpms16;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=11402041; DOI=10.1074/jbc.m103236200;
RA Suzuki T., Terasaki M., Takemoto-Hori C., Hanada T., Ueda T., Wada A.,
RA Watanabe K.;
RT "Proteomic analysis of the mammalian mitochondrial ribosome. Identification
RT of protein components in the 28S small subunit.";
RL J. Biol. Chem. 276:33181-33195(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Cerebellum, and Embryo;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Mammary tumor;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Brown adipose tissue, Heart, Kidney, Liver, and Testis;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC -!- SUBUNIT: Component of the mitochondrial ribosome small subunit (28S)
CC which comprises a 12S rRNA and about 30 distinct proteins.
CC {ECO:0000250|UniProtKB:Q9Y3D3}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q9Y3D3}.
CC -!- SIMILARITY: Belongs to the bacterial ribosomal protein bS16 family.
CC {ECO:0000305}.
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DR EMBL; AB049949; BAB41002.1; -; mRNA.
DR EMBL; AK019243; BAB31623.1; -; mRNA.
DR EMBL; AK005206; BAB23884.1; -; mRNA.
DR EMBL; BC024656; AAH24656.1; -; mRNA.
DR CCDS; CCDS36817.1; -.
DR RefSeq; NP_079716.1; NM_025440.2.
DR AlphaFoldDB; Q9CPX7; -.
DR SMR; Q9CPX7; -.
DR BioGRID; 211321; 2.
DR ComplexPortal; CPX-5301; 28S mitochondrial small ribosomal subunit.
DR STRING; 10090.ENSMUSP00000055619; -.
DR PhosphoSitePlus; Q9CPX7; -.
DR SwissPalm; Q9CPX7; -.
DR EPD; Q9CPX7; -.
DR MaxQB; Q9CPX7; -.
DR PaxDb; Q9CPX7; -.
DR PeptideAtlas; Q9CPX7; -.
DR PRIDE; Q9CPX7; -.
DR ProteomicsDB; 257046; -.
DR Antibodypedia; 45368; 127 antibodies from 23 providers.
DR DNASU; 66242; -.
DR Ensembl; ENSMUST00000061444; ENSMUSP00000055619; ENSMUSG00000049960.
DR GeneID; 66242; -.
DR KEGG; mmu:66242; -.
DR UCSC; uc007sjp.1; mouse.
DR CTD; 51021; -.
DR MGI; MGI:1913492; Mrps16.
DR VEuPathDB; HostDB:ENSMUSG00000049960; -.
DR eggNOG; KOG3419; Eukaryota.
DR GeneTree; ENSGT00390000014309; -.
DR HOGENOM; CLU_100590_4_0_1; -.
DR InParanoid; Q9CPX7; -.
DR OMA; HMSEPAA; -.
DR OrthoDB; 1630052at2759; -.
DR PhylomeDB; Q9CPX7; -.
DR TreeFam; TF105637; -.
DR Reactome; R-MMU-5389840; Mitochondrial translation elongation.
DR Reactome; R-MMU-5419276; Mitochondrial translation termination.
DR BioGRID-ORCS; 66242; 23 hits in 71 CRISPR screens.
DR ChiTaRS; Mrps16; mouse.
DR PRO; PR:Q9CPX7; -.
DR Proteomes; UP000000589; Chromosome 14.
DR RNAct; Q9CPX7; protein.
DR Bgee; ENSMUSG00000049960; Expressed in digastric muscle group and 250 other tissues.
DR Genevisible; Q9CPX7; MM.
DR GO; GO:0005829; C:cytosol; ISO:MGI.
DR GO; GO:0005743; C:mitochondrial inner membrane; IC:ComplexPortal.
DR GO; GO:0005763; C:mitochondrial small ribosomal subunit; ISS:UniProtKB.
DR GO; GO:0005739; C:mitochondrion; HDA:MGI.
DR GO; GO:0015935; C:small ribosomal subunit; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; ISS:UniProtKB.
DR GO; GO:0032543; P:mitochondrial translation; ISS:UniProtKB.
DR Gene3D; 3.30.1320.10; -; 1.
DR HAMAP; MF_00385; Ribosomal_S16; 1.
DR InterPro; IPR000307; Ribosomal_S16.
DR InterPro; IPR023803; Ribosomal_S16_dom_sf.
DR PANTHER; PTHR12919; PTHR12919; 1.
DR Pfam; PF00886; Ribosomal_S16; 1.
DR SUPFAM; SSF54565; SSF54565; 1.
DR TIGRFAMs; TIGR00002; S16; 1.
PE 1: Evidence at protein level;
KW Mitochondrion; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW Transit peptide.
FT TRANSIT 1..34
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 35..135
FT /note="28S ribosomal protein S16, mitochondrial"
FT /id="PRO_0000030619"
SQ SEQUENCE 135 AA; 15192 MW; EBA2A7209177B50C CRC64;
MVQLTTIFCK AYHGGHLTIR LALGGCTNRP FYRIVAAHNK CPRDGRFVEQ LGSYDPLPNS
HGEKLVALNL DRIRHWIGCG AHLSKPMEKL LGLSGFFPLH PMMITNAERL RRRRAREVLL
ASQKAESEAK ETEAS
