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RT18A_BOVIN
ID   RT18A_BOVIN             Reviewed;         196 AA.
AC   P82919; A6QLH4;
DT   19-OCT-2002, integrated into UniProtKB/Swiss-Prot.
DT   26-FEB-2008, sequence version 3.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=28S ribosomal protein S18a, mitochondrial;
DE            Short=MRP-S18-a;
DE            Short=Mrps18a;
DE            Short=S18mt-a;
DE   AltName: Full=28S ribosomal protein S18-3, mitochondrial;
DE            Short=MRP-S18-3;
DE   Flags: Precursor;
GN   Name=MRPS18A;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913 {ECO:0000305};
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Hypothalamus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   PROTEIN SEQUENCE OF 35-47, SUBCELLULAR LOCATION, AND SUBUNIT.
RX   PubMed=11402041; DOI=10.1074/jbc.m103236200;
RA   Suzuki T., Terasaki M., Takemoto-Hori C., Hanada T., Ueda T., Wada A.,
RA   Watanabe K.;
RT   "Proteomic analysis of the mammalian mitochondrial ribosome. Identification
RT   of protein components in the 28S small subunit.";
RL   J. Biol. Chem. 276:33181-33195(2001).
RN   [3] {ECO:0000305}
RP   PROTEIN SEQUENCE OF 174-196, SUBCELLULAR LOCATION, AND SUBUNIT.
RC   TISSUE=Liver;
RX   PubMed=11279123; DOI=10.1074/jbc.m100727200;
RA   Koc E.C., Burkhart W., Blackburn K., Moseley A., Spremulli L.L.;
RT   "The small subunit of the mammalian mitochondrial ribosome: identification
RT   of the full complement of ribosomal proteins present.";
RL   J. Biol. Chem. 276:19363-19374(2001).
RN   [4] {ECO:0007744|PDB:3JD5}
RP   STRUCTURE BY ELECTRON MICROSCOPY (7.00 ANGSTROMS), SUBCELLULAR LOCATION,
RP   AND SUBUNIT.
RX   PubMed=24799711; DOI=10.1073/pnas.1401657111;
RA   Kaushal P.S., Sharma M.R., Booth T.M., Haque E.M., Tung C.S.,
RA   Sanbonmatsu K.Y., Spremulli L.L., Agrawal R.K.;
RT   "Cryo-EM structure of the small subunit of the mammalian mitochondrial
RT   ribosome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 111:7284-7289(2014).
CC   -!- SUBUNIT: Component of the mitochondrial ribosome small subunit (28S)
CC       which comprises a 12S rRNA and about 30 distinct proteins.
CC       {ECO:0000269|PubMed:11279123, ECO:0000269|PubMed:11402041,
CC       ECO:0000269|PubMed:24799711}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:11279123,
CC       ECO:0000269|PubMed:11402041, ECO:0000269|PubMed:24799711}.
CC   -!- SIMILARITY: Belongs to the bacterial ribosomal protein bS18 family.
CC       Mitochondrion-specific ribosomal protein mL66 subfamily. {ECO:0000305}.
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DR   EMBL; BC147966; AAI47967.1; -; mRNA.
DR   RefSeq; NP_001094699.1; NM_001101229.2.
DR   PDB; 3JD5; EM; 7.00 A; R=1-196.
DR   PDBsum; 3JD5; -.
DR   AlphaFoldDB; P82919; -.
DR   SMR; P82919; -.
DR   CORUM; P82919; -.
DR   IntAct; P82919; 1.
DR   STRING; 9913.ENSBTAP00000051782; -.
DR   PaxDb; P82919; -.
DR   GeneID; 614102; -.
DR   KEGG; bta:614102; -.
DR   CTD; 55168; -.
DR   eggNOG; KOG3162; Eukaryota.
DR   InParanoid; P82919; -.
DR   OrthoDB; 1619493at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005743; C:mitochondrial inner membrane; TAS:Reactome.
DR   GO; GO:0005763; C:mitochondrial small ribosomal subunit; HDA:UniProtKB.
DR   GO; GO:0070181; F:small ribosomal subunit rRNA binding; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; HDA:UniProtKB.
DR   GO; GO:0032543; P:mitochondrial translation; HDA:UniProtKB.
DR   Gene3D; 4.10.640.10; -; 1.
DR   InterPro; IPR001648; Ribosomal_S18.
DR   InterPro; IPR036870; Ribosomal_S18_sf.
DR   PANTHER; PTHR13479; PTHR13479; 1.
DR   Pfam; PF01084; Ribosomal_S18; 1.
DR   SUPFAM; SSF46911; SSF46911; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Direct protein sequencing; Mitochondrion; Reference proteome;
KW   Ribonucleoprotein; Ribosomal protein; Transit peptide.
FT   TRANSIT         1..34
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000269|PubMed:11402041"
FT   CHAIN           35..196
FT                   /note="28S ribosomal protein S18a, mitochondrial"
FT                   /id="PRO_0000111315"
SQ   SEQUENCE   196 AA;  22281 MW;  0CAA7B308EAD5CF1 CRC64;
     MAALNVLVSG CGRFLRGLLT GPTVTSWARP PARGFREVVE IQEGKTTIIE GRITGTPKES
     PNPPNPSGQC PICRWNLKHK YSYEDVLLLS QFIRPHGGML PRSITGLCQE EHRKIEECVK
     MAHRAGLLPN HRPKLPEGFF PKTRPRLNRY LTRWSPRSVK PIYNKGHRWN KVRMAVGSPL
     LKDNVSYTGR PLVLYH
 
 
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