RT18B_BOVIN
ID RT18B_BOVIN Reviewed; 258 AA.
AC P82918; Q2TBM4;
DT 19-OCT-2002, integrated into UniProtKB/Swiss-Prot.
DT 13-JUN-2006, sequence version 2.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=28S ribosomal protein S18b, mitochondrial;
DE Short=MRP-S18-b;
DE Short=Mrps18-b;
DE Short=S18mt-b;
DE AltName: Full=28S ribosomal protein S18-2, mitochondrial;
DE Short=MRP-S18-2;
DE Flags: Precursor;
GN Name=MRPS18B {ECO:0000250|UniProtKB:Q9Y676};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1] {ECO:0000312|EMBL:AAI09914.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Crossbred X Angus {ECO:0000312|EMBL:AAI09914.1};
RC TISSUE=Liver {ECO:0000312|EMBL:AAI09914.1};
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000305}
RP PROTEIN SEQUENCE OF 36-56 AND 156-173, SUBCELLULAR LOCATION, AND SUBUNIT.
RC TISSUE=Liver {ECO:0000269|PubMed:11279123};
RX PubMed=11279123; DOI=10.1074/jbc.m100727200;
RA Koc E.C., Burkhart W., Blackburn K., Moseley A., Spremulli L.L.;
RT "The small subunit of the mammalian mitochondrial ribosome: identification
RT of the full complement of ribosomal proteins present.";
RL J. Biol. Chem. 276:19363-19374(2001).
RN [3] {ECO:0007744|PDB:3JD5}
RP STRUCTURE BY ELECTRON MICROSCOPY (7.00 ANGSTROMS), SUBCELLULAR LOCATION,
RP AND SUBUNIT.
RX PubMed=24799711; DOI=10.1073/pnas.1401657111;
RA Kaushal P.S., Sharma M.R., Booth T.M., Haque E.M., Tung C.S.,
RA Sanbonmatsu K.Y., Spremulli L.L., Agrawal R.K.;
RT "Cryo-EM structure of the small subunit of the mammalian mitochondrial
RT ribosome.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:7284-7289(2014).
CC -!- SUBUNIT: Component of the mitochondrial ribosome small subunit (28S)
CC which comprises a 12S rRNA and about 30 distinct proteins.
CC {ECO:0000269|PubMed:11279123, ECO:0000269|PubMed:24799711}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:11279123,
CC ECO:0000269|PubMed:24799711}.
CC -!- SIMILARITY: Belongs to the bacterial ribosomal protein bS18 family.
CC Mitochondrion-specific ribosomal protein mS40 subfamily. {ECO:0000305}.
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DR EMBL; BC109913; AAI09914.1; -; mRNA.
DR RefSeq; NP_001033613.1; NM_001038524.1.
DR PDB; 3JD5; EM; 7.00 A; p=1-258.
DR PDB; 6NEQ; EM; 3.32 A; p=1-258.
DR PDB; 6NF8; EM; 3.48 A; p=1-258.
DR PDBsum; 3JD5; -.
DR PDBsum; 6NEQ; -.
DR PDBsum; 6NF8; -.
DR AlphaFoldDB; P82918; -.
DR SMR; P82918; -.
DR CORUM; P82918; -.
DR IntAct; P82918; 2.
DR STRING; 9913.ENSBTAP00000009107; -.
DR iPTMnet; P82918; -.
DR PaxDb; P82918; -.
DR PRIDE; P82918; -.
DR GeneID; 510824; -.
DR KEGG; bta:510824; -.
DR CTD; 28973; -.
DR eggNOG; KOG4021; Eukaryota.
DR InParanoid; P82918; -.
DR Proteomes; UP000009136; Unplaced.
DR GO; GO:0005743; C:mitochondrial inner membrane; TAS:Reactome.
DR GO; GO:0005763; C:mitochondrial small ribosomal subunit; IDA:UniProtKB.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; HDA:UniProtKB.
DR GO; GO:0032543; P:mitochondrial translation; HDA:UniProtKB.
DR Gene3D; 4.10.640.10; -; 1.
DR InterPro; IPR040054; MRPS18B.
DR InterPro; IPR001648; Ribosomal_S18.
DR InterPro; IPR036870; Ribosomal_S18_sf.
DR PANTHER; PTHR13329; PTHR13329; 1.
DR Pfam; PF01084; Ribosomal_S18; 1.
DR SUPFAM; SSF46911; SSF46911; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Direct protein sequencing; Mitochondrion; Phosphoprotein;
KW Reference proteome; Ribonucleoprotein; Ribosomal protein; Transit peptide.
FT TRANSIT 1..35
FT /note="Mitochondrion"
FT /evidence="ECO:0000269|PubMed:11279123"
FT CHAIN 36..258
FT /note="28S ribosomal protein S18b, mitochondrial"
FT /id="PRO_0000111316"
FT REGION 221..258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 241..258
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 49
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9Y676"
FT CONFLICT 47
FT /note="P -> H (in Ref. 1; AAI09914)"
FT /evidence="ECO:0000305"
FT HELIX 56..60
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 62..67
FT /evidence="ECO:0007829|PDB:6NEQ"
FT TURN 68..70
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 82..85
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 94..98
FT /evidence="ECO:0007829|PDB:6NEQ"
FT TURN 106..109
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 120..123
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 124..126
FT /evidence="ECO:0007829|PDB:6NEQ"
FT TURN 129..131
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 137..140
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 144..160
FT /evidence="ECO:0007829|PDB:6NEQ"
FT TURN 182..184
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 191..195
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 201..203
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 211..219
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 220..223
FT /evidence="ECO:0007829|PDB:6NEQ"
SQ SEQUENCE 258 AA; 29174 MW; EC704F50FB1E0CFE CRC64;
MAASVLNVLL RRLPYFSPFR GAYGVQVPLQ TLCTKAPPED DSLPPIPVSP YEDEPWKYLD
SEEYHNRNGS RPVWADYRRN HKGGIPPQRT RKMCIRGNKV AGNPCPICRD QKLHVDFRNV
KLLKQFVCAH TGIIFHAPYT GVCMKQHKKL TQAIQKARDH GLLSYHIPQV EPRDLDFSTS
HGAVSATPPA PTLVSGDPWY PWYSWKQPPE RELSRLRRLY QGHLREESGP PPESMPKVPL
TAPNEATSTE QAGPQSAL
