RT18B_PIG
ID RT18B_PIG Reviewed; 258 AA.
AC Q767K8;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=28S ribosomal protein S18b, mitochondrial;
DE Short=MRP-S18-b;
DE Short=Mrps18-b;
DE Short=S18mt-b;
DE AltName: Full=28S ribosomal protein S18-2, mitochondrial;
DE Short=MRP-S18-2;
DE Flags: Precursor;
GN Name=MRPS18B;
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Large white;
RX PubMed=14673549; DOI=10.1007/s00251-003-0627-0;
RA Shigenari A., Ando A., Renard C., Chardon P., Shiina T., Kulski J.K.,
RA Yasue H., Inoko H.;
RT "Nucleotide sequencing analysis of the swine 433-kb genomic segment located
RT between the non-classical and classical SLA class I gene clusters.";
RL Immunogenetics 55:695-705(2004).
RN [2] {ECO:0007744|PDB:5AJ3, ECO:0007744|PDB:5AJ4}
RP STRUCTURE BY ELECTRON MICROSCOPY (3.60 ANGSTROMS), SUBCELLULAR LOCATION,
RP AND SUBUNIT.
RX PubMed=25837512; DOI=10.1126/science.aaa3872;
RA Greber B.J., Bieri P., Leibundgut M., Leitner A., Aebersold R.,
RA Boehringer D., Ban N.;
RT "Ribosome. The complete structure of the 55S mammalian mitochondrial
RT ribosome.";
RL Science 348:303-308(2015).
CC -!- SUBUNIT: Component of the mitochondrial ribosome small subunit (28S)
CC which comprises a 12S rRNA and about 30 distinct proteins.
CC {ECO:0000269|PubMed:25837512}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:25837512}.
CC -!- SIMILARITY: Belongs to the bacterial ribosomal protein bS18 family.
CC Mitochondrion-specific ribosomal protein mS40 subfamily. {ECO:0000305}.
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DR EMBL; AB113356; BAD08429.1; -; Genomic_DNA.
DR EMBL; AB113357; BAD08441.1; -; Genomic_DNA.
DR RefSeq; NP_001116612.1; NM_001123140.1.
DR PDB; 5AJ3; EM; 3.60 A; p=1-258.
DR PDB; 5AJ4; EM; 3.80 A; Ap=51-238.
DR PDB; 6GAW; EM; 3.20 A; Ap=1-258.
DR PDB; 6GAZ; EM; 3.10 A; Ap=1-258.
DR PDB; 6YDP; EM; 3.00 A; Ap=1-258.
DR PDB; 6YDW; EM; 4.20 A; Ap=1-258.
DR PDB; 7NQH; EM; 3.50 A; Ap=1-258.
DR PDB; 7NQL; EM; 3.40 A; Ap=1-258.
DR PDB; 7NSI; EM; 4.60 A; Ap=1-258.
DR PDB; 7NSJ; EM; 3.90 A; Ap=1-258.
DR PDBsum; 5AJ3; -.
DR PDBsum; 5AJ4; -.
DR PDBsum; 6GAW; -.
DR PDBsum; 6GAZ; -.
DR PDBsum; 6YDP; -.
DR PDBsum; 6YDW; -.
DR PDBsum; 7NQH; -.
DR PDBsum; 7NQL; -.
DR PDBsum; 7NSI; -.
DR PDBsum; 7NSJ; -.
DR AlphaFoldDB; Q767K8; -.
DR SMR; Q767K8; -.
DR STRING; 9823.ENSSSCP00000024944; -.
DR PaxDb; Q767K8; -.
DR PRIDE; Q767K8; -.
DR Ensembl; ENSSSCT00000027559; ENSSSCP00000024944; ENSSSCG00000029425.
DR Ensembl; ENSSSCT00005015439; ENSSSCP00005009206; ENSSSCG00005010016.
DR Ensembl; ENSSSCT00015044086; ENSSSCP00015017438; ENSSSCG00015032778.
DR Ensembl; ENSSSCT00025108291; ENSSSCP00025049036; ENSSSCG00025077792.
DR Ensembl; ENSSSCT00030086090; ENSSSCP00030039692; ENSSSCG00030061571.
DR Ensembl; ENSSSCT00035085417; ENSSSCP00035035561; ENSSSCG00035063512.
DR Ensembl; ENSSSCT00045068521; ENSSSCP00045048757; ENSSSCG00045039367.
DR Ensembl; ENSSSCT00050022550; ENSSSCP00050009545; ENSSSCG00050016533.
DR Ensembl; ENSSSCT00055061023; ENSSSCP00055048925; ENSSSCG00055030616.
DR Ensembl; ENSSSCT00060069119; ENSSSCP00060029737; ENSSSCG00060050808.
DR Ensembl; ENSSSCT00065076783; ENSSSCP00065033393; ENSSSCG00065056075.
DR Ensembl; ENSSSCT00070049219; ENSSSCP00070041572; ENSSSCG00070024659.
DR GeneID; 100144465; -.
DR KEGG; ssc:100144465; -.
DR CTD; 28973; -.
DR VGNC; VGNC:90385; MRPS18B.
DR eggNOG; KOG4021; Eukaryota.
DR GeneTree; ENSGT00390000010554; -.
DR HOGENOM; CLU_089746_0_0_1; -.
DR InParanoid; Q767K8; -.
DR OMA; PWEYLET; -.
DR OrthoDB; 1023024at2759; -.
DR TreeFam; TF315059; -.
DR Reactome; R-SSC-5389840; Mitochondrial translation elongation.
DR Reactome; R-SSC-5419276; Mitochondrial translation termination.
DR Proteomes; UP000008227; Chromosome 7.
DR Proteomes; UP000314985; Chromosome 7.
DR Bgee; ENSSSCG00000029425; Expressed in semimembranosus muscle and 44 other tissues.
DR ExpressionAtlas; Q767K8; baseline and differential.
DR Genevisible; Q767K8; SS.
DR GO; GO:0030054; C:cell junction; IEA:Ensembl.
DR GO; GO:0005763; C:mitochondrial small ribosomal subunit; IDA:UniProtKB.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0032543; P:mitochondrial translation; IEA:InterPro.
DR Gene3D; 4.10.640.10; -; 1.
DR InterPro; IPR040054; MRPS18B.
DR InterPro; IPR001648; Ribosomal_S18.
DR InterPro; IPR036870; Ribosomal_S18_sf.
DR PANTHER; PTHR13329; PTHR13329; 1.
DR Pfam; PF01084; Ribosomal_S18; 1.
DR SUPFAM; SSF46911; SSF46911; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Mitochondrion; Phosphoprotein; Reference proteome;
KW Ribonucleoprotein; Ribosomal protein; Transit peptide.
FT TRANSIT 1..35
FT /note="Mitochondrion"
FT /evidence="ECO:0000250|UniProtKB:P82918"
FT CHAIN 36..258
FT /note="28S ribosomal protein S18b, mitochondrial"
FT /id="PRO_0000317427"
FT REGION 223..258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 49
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9Y676"
SQ SEQUENCE 258 AA; 29178 MW; 16DAF5EF35D95070 CRC64;
MAASILNVLL RRLPGVSPFR GAYGVQVLLQ TLCTKAPPED DSLPQVPISP YKDEPWKYLD
SEEYQNRYGS RPVWADYRRN HKGGIPPQRT RKMCIRGNKV AGNPCPICRD QKLHVDFRNV
KLLEQFVCAH TGIIFHAPYT GVCMKQHKKL TQAIQKARDH GLLRYHIPQV EPRDLDFSTT
HGAVSSTPPA PTLVSGDPWY PWYSWKQPPE RELSRLRRLY QGRLREESGP PPELMPEVPL
TAPAEASSTE PGAPQSAL
