RT18C_BOVIN
ID RT18C_BOVIN Reviewed; 143 AA.
AC P82917; Q2KI03;
DT 19-OCT-2002, integrated into UniProtKB/Swiss-Prot.
DT 13-JUN-2006, sequence version 2.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=28S ribosomal protein S18c, mitochondrial;
DE Short=MRP-S18-c;
DE Short=Mrps18-c;
DE Short=S18mt-c;
DE AltName: Full=28S ribosomal protein S18-1, mitochondrial;
DE Short=MRP-S18-1;
DE Flags: Precursor;
GN Name=MRPS18C;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000305};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Heart ventricle;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000305}
RP PROTEIN SEQUENCE OF 44-64 AND 96-103, SUBCELLULAR LOCATION, AND SUBUNIT.
RC TISSUE=Liver;
RX PubMed=11279123; DOI=10.1074/jbc.m100727200;
RA Koc E.C., Burkhart W., Blackburn K., Moseley A., Spremulli L.L.;
RT "The small subunit of the mammalian mitochondrial ribosome: identification
RT of the full complement of ribosomal proteins present.";
RL J. Biol. Chem. 276:19363-19374(2001).
RN [3] {ECO:0007744|PDB:3JD5}
RP STRUCTURE BY ELECTRON MICROSCOPY (7.00 ANGSTROMS), SUBCELLULAR LOCATION,
RP AND SUBUNIT.
RX PubMed=24799711; DOI=10.1073/pnas.1401657111;
RA Kaushal P.S., Sharma M.R., Booth T.M., Haque E.M., Tung C.S.,
RA Sanbonmatsu K.Y., Spremulli L.L., Agrawal R.K.;
RT "Cryo-EM structure of the small subunit of the mammalian mitochondrial
RT ribosome.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:7284-7289(2014).
CC -!- SUBUNIT: Component of the mitochondrial ribosome small subunit (28S)
CC which comprises a 12S rRNA and about 30 distinct proteins.
CC {ECO:0000269|PubMed:11279123, ECO:0000269|PubMed:24799711}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:11279123,
CC ECO:0000269|PubMed:24799711}.
CC -!- SIMILARITY: Belongs to the bacterial ribosomal protein bS18 family.
CC {ECO:0000305}.
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DR EMBL; BC112818; AAI12819.1; -; mRNA.
DR RefSeq; NP_001039973.1; NM_001046508.1.
DR PDB; 3JD5; EM; 7.00 A; R=1-143.
DR PDB; 6NEQ; EM; 3.32 A; R=1-143.
DR PDB; 6NF8; EM; 3.48 A; R=1-143.
DR PDBsum; 3JD5; -.
DR PDBsum; 6NEQ; -.
DR PDBsum; 6NF8; -.
DR AlphaFoldDB; P82917; -.
DR SMR; P82917; -.
DR CORUM; P82917; -.
DR IntAct; P82917; 2.
DR STRING; 9913.ENSBTAP00000024161; -.
DR PaxDb; P82917; -.
DR PRIDE; P82917; -.
DR Ensembl; ENSBTAT00000024161; ENSBTAP00000024161; ENSBTAG00000018155.
DR GeneID; 613561; -.
DR KEGG; bta:613561; -.
DR CTD; 51023; -.
DR VEuPathDB; HostDB:ENSBTAG00000018155; -.
DR VGNC; VGNC:31659; MRPS18C.
DR eggNOG; KOG3162; Eukaryota.
DR GeneTree; ENSGT00390000003791; -.
DR HOGENOM; CLU_139337_2_0_1; -.
DR InParanoid; P82917; -.
DR OMA; GYHKDLD; -.
DR OrthoDB; 1592020at2759; -.
DR TreeFam; TF315059; -.
DR Proteomes; UP000009136; Chromosome 6.
DR Bgee; ENSBTAG00000018155; Expressed in oocyte and 105 other tissues.
DR ExpressionAtlas; P82917; baseline and differential.
DR GO; GO:0005743; C:mitochondrial inner membrane; TAS:Reactome.
DR GO; GO:0005763; C:mitochondrial small ribosomal subunit; IDA:UniProtKB.
DR GO; GO:0070181; F:small ribosomal subunit rRNA binding; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR Gene3D; 4.10.640.10; -; 1.
DR InterPro; IPR001648; Ribosomal_S18.
DR InterPro; IPR018275; Ribosomal_S18_CS.
DR InterPro; IPR036870; Ribosomal_S18_sf.
DR PANTHER; PTHR13479; PTHR13479; 1.
DR Pfam; PF01084; Ribosomal_S18; 1.
DR PRINTS; PR00974; RIBOSOMALS18.
DR SUPFAM; SSF46911; SSF46911; 1.
DR TIGRFAMs; TIGR00165; S18; 1.
DR PROSITE; PS00057; RIBOSOMAL_S18; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Direct protein sequencing; Mitochondrion; Reference proteome;
KW Ribonucleoprotein; Ribosomal protein; Transit peptide.
FT TRANSIT 1..?
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN ?..143
FT /note="28S ribosomal protein S18c, mitochondrial"
FT /id="PRO_0000111317"
FT STRAND 67..70
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 78..81
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 82..84
FT /evidence="ECO:0007829|PDB:6NEQ"
FT TURN 87..89
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 95..98
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 102..117
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 123..125
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 128..130
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 131..133
FT /evidence="ECO:0007829|PDB:6NF8"
SQ SEQUENCE 143 AA; 16214 MW; 94B8CE6620110CC8 CRC64;
MAAVLGLCGG LGKRKFTRFP TAFVCLTNSG TRAVLWRSCS QCKQVTSSED LPIPMENPYK
EPLKKCILCE KRVDYKNVQL LSQFISPFTG CIYGRHITGL CGKKQREITK AIKRAQILGF
MPVTYKDPAY LKDPKVCNIR YRE
