RT21_BOVIN
ID RT21_BOVIN Reviewed; 87 AA.
AC P82920; Q2HJ36;
DT 04-MAY-2001, integrated into UniProtKB/Swiss-Prot.
DT 13-JUN-2006, sequence version 3.
DT 03-AUG-2022, entry version 119.
DE RecName: Full=28S ribosomal protein S21, mitochondrial;
DE Short=MRP-S21;
DE Short=S21mt;
GN Name=MRPS21; Synonyms=RPMS21;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Uterus;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP PROTEIN SEQUENCE OF 44-50 AND 72-87, AND SUBCELLULAR LOCATION.
RC TISSUE=Liver;
RX PubMed=11279123; DOI=10.1074/jbc.m100727200;
RA Koc E.C., Burkhart W., Blackburn K., Moseley A., Spremulli L.L.;
RT "The small subunit of the mammalian mitochondrial ribosome: identification
RT of the full complement of ribosomal proteins present.";
RL J. Biol. Chem. 276:19363-19374(2001).
RN [3] {ECO:0007744|PDB:3JD5}
RP STRUCTURE BY ELECTRON MICROSCOPY (7.00 ANGSTROMS), SUBCELLULAR LOCATION,
RP AND SUBUNIT.
RX PubMed=24799711; DOI=10.1073/pnas.1401657111;
RA Kaushal P.S., Sharma M.R., Booth T.M., Haque E.M., Tung C.S.,
RA Sanbonmatsu K.Y., Spremulli L.L., Agrawal R.K.;
RT "Cryo-EM structure of the small subunit of the mammalian mitochondrial
RT ribosome.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:7284-7289(2014).
CC -!- SUBUNIT: Component of the mitochondrial ribosome small subunit (28S)
CC which comprises a 12S rRNA and about 30 distinct proteins.
CC {ECO:0000269|PubMed:24799711}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:11279123,
CC ECO:0000269|PubMed:24799711}.
CC -!- SIMILARITY: Belongs to the bacterial ribosomal protein bS21 family.
CC {ECO:0000305}.
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DR EMBL; BC113330; AAI13331.1; -; mRNA.
DR RefSeq; NP_001106778.1; NM_001113307.1.
DR RefSeq; XP_005203988.1; XM_005203931.1.
DR RefSeq; XP_010801346.1; XM_010803044.1.
DR PDB; 3JD5; EM; 7.00 A; U=1-87.
DR PDB; 6NEQ; EM; 3.32 A; U=1-87.
DR PDB; 6NF8; EM; 3.48 A; U=1-87.
DR PDBsum; 3JD5; -.
DR PDBsum; 6NEQ; -.
DR PDBsum; 6NF8; -.
DR AlphaFoldDB; P82920; -.
DR SMR; P82920; -.
DR CORUM; P82920; -.
DR IntAct; P82920; 2.
DR STRING; 9913.ENSBTAP00000033682; -.
DR PaxDb; P82920; -.
DR Ensembl; ENSBTAT00000033773; ENSBTAP00000033682; ENSBTAG00000024378.
DR GeneID; 614343; -.
DR KEGG; bta:614343; -.
DR CTD; 54460; -.
DR VEuPathDB; HostDB:ENSBTAG00000024378; -.
DR VGNC; VGNC:31661; MRPS21.
DR eggNOG; ENOG502S4BS; Eukaryota.
DR GeneTree; ENSGT00500000045038; -.
DR HOGENOM; CLU_167771_0_0_1; -.
DR InParanoid; P82920; -.
DR OMA; MRHAQFL; -.
DR OrthoDB; 1512634at2759; -.
DR TreeFam; TF313903; -.
DR Proteomes; UP000009136; Chromosome 3.
DR Bgee; ENSBTAG00000024378; Expressed in semen and 108 other tissues.
DR GO; GO:0005743; C:mitochondrial inner membrane; TAS:Reactome.
DR GO; GO:0005763; C:mitochondrial small ribosomal subunit; IDA:UniProtKB.
DR GO; GO:0003735; F:structural constituent of ribosome; HDA:UniProtKB.
DR GO; GO:0032543; P:mitochondrial translation; HDA:UniProtKB.
DR Gene3D; 1.20.5.1150; -; 1.
DR InterPro; IPR001911; Ribosomal_S21.
DR InterPro; IPR038380; S21_sf.
DR PANTHER; PTHR21109; PTHR21109; 1.
DR Pfam; PF01165; Ribosomal_S21; 1.
DR TIGRFAMs; TIGR00030; S21p; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Direct protein sequencing; Mitochondrion; Reference proteome;
KW Ribonucleoprotein; Ribosomal protein.
FT CHAIN 1..87
FT /note="28S ribosomal protein S21, mitochondrial"
FT /id="PRO_0000178412"
FT STRAND 6..13
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 15..17
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 20..33
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 36..43
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 48..74
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 77..79
FT /evidence="ECO:0007829|PDB:6NEQ"
SQ SEQUENCE 87 AA; 10676 MW; D28696851F9150E7 CRC64;
MAKHLKFIAR TVMVQEGNVE GAYRTLNRIL TMDGLIEDIK RRRYYEKPCR RRQRESYETC
RRIYNMEMAR KINFLMRKNR ADPWQGC