RT25_BOVIN
ID RT25_BOVIN Reviewed; 173 AA.
AC P82669; Q32P88;
DT 27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT 13-JUN-2006, sequence version 2.
DT 03-AUG-2022, entry version 119.
DE RecName: Full=28S ribosomal protein S25, mitochondrial;
DE Short=MRP-S25;
DE Short=S25mt;
GN Name=MRPS25; Synonyms=RPMS25;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Crossbred X Angus; TISSUE=Liver;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP PROTEIN SEQUENCE OF 29-44 AND 77-93.
RC TISSUE=Liver;
RX PubMed=10938081; DOI=10.1074/jbc.m003596200;
RA Koc E.C., Burkhart W., Blackburn K., Moseley A., Koc H., Spremulli L.L.;
RT "A proteomics approach to the identification of mammalian mitochondrial
RT small subunit ribosomal proteins.";
RL J. Biol. Chem. 275:32585-32591(2000).
RN [3] {ECO:0007744|PDB:3JD5}
RP STRUCTURE BY ELECTRON MICROSCOPY (7.00 ANGSTROMS), SUBCELLULAR LOCATION,
RP AND SUBUNIT.
RX PubMed=24799711; DOI=10.1073/pnas.1401657111;
RA Kaushal P.S., Sharma M.R., Booth T.M., Haque E.M., Tung C.S.,
RA Sanbonmatsu K.Y., Spremulli L.L., Agrawal R.K.;
RT "Cryo-EM structure of the small subunit of the mammalian mitochondrial
RT ribosome.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:7284-7289(2014).
CC -!- SUBUNIT: Component of the mitochondrial ribosome small subunit (28S)
CC which comprises a 12S rRNA and about 30 distinct proteins.
CC {ECO:0000269|PubMed:24799711}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:24799711}.
CC -!- SIMILARITY: Belongs to the mitochondrion-specific ribosomal protein
CC mS25 family. {ECO:0000305}.
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DR EMBL; BC108214; AAI08215.1; -; mRNA.
DR RefSeq; NP_001069447.1; NM_001075979.2.
DR PDB; 3JD5; EM; 7.00 A; c=1-173.
DR PDB; 6NEQ; EM; 3.32 A; c=1-173.
DR PDB; 6NF8; EM; 3.48 A; c=1-173.
DR PDBsum; 3JD5; -.
DR PDBsum; 6NEQ; -.
DR PDBsum; 6NF8; -.
DR AlphaFoldDB; P82669; -.
DR SMR; P82669; -.
DR CORUM; P82669; -.
DR IntAct; P82669; 1.
DR STRING; 9913.ENSBTAP00000018234; -.
DR PaxDb; P82669; -.
DR Ensembl; ENSBTAT00000018234; ENSBTAP00000018234; ENSBTAG00000013723.
DR GeneID; 533011; -.
DR KEGG; bta:533011; -.
DR CTD; 64432; -.
DR VEuPathDB; HostDB:ENSBTAG00000013723; -.
DR VGNC; VGNC:31665; MRPS25.
DR eggNOG; KOG4079; Eukaryota.
DR GeneTree; ENSGT00640000091558; -.
DR HOGENOM; CLU_094727_0_0_1; -.
DR InParanoid; P82669; -.
DR OMA; QIMLFRN; -.
DR OrthoDB; 1438394at2759; -.
DR TreeFam; TF300292; -.
DR Proteomes; UP000009136; Chromosome 22.
DR Bgee; ENSBTAG00000013723; Expressed in corpus epididymis and 105 other tissues.
DR GO; GO:0005743; C:mitochondrial inner membrane; TAS:Reactome.
DR GO; GO:0005763; C:mitochondrial small ribosomal subunit; IDA:UniProtKB.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IDA:MGI.
DR GO; GO:0032543; P:mitochondrial translation; HDA:UniProtKB.
DR InterPro; IPR040049; MRPS25.
DR InterPro; IPR007741; Ribosome/NADH_DH.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR13274; PTHR13274; 1.
DR Pfam; PF05047; L51_S25_CI-B8; 1.
DR SMART; SM00916; L51_S25_CI-B8; 1.
DR SUPFAM; SSF52833; SSF52833; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Direct protein sequencing; Mitochondrion; Reference proteome;
KW Ribonucleoprotein; Ribosomal protein.
FT CHAIN 1..173
FT /note="28S ribosomal protein S25, mitochondrial"
FT /id="PRO_0000087707"
FT STRAND 4..6
FT /evidence="ECO:0007829|PDB:6NEQ"
FT TURN 8..11
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 13..16
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 27..34
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 36..39
FT /evidence="ECO:0007829|PDB:6NF8"
FT HELIX 42..57
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 62..70
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 75..83
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 85..89
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 95..105
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 110..123
FT /evidence="ECO:0007829|PDB:6NEQ"
FT TURN 132..134
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 135..138
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 140..142
FT /evidence="ECO:0007829|PDB:6NEQ"
FT TURN 150..152
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 161..167
FT /evidence="ECO:0007829|PDB:6NEQ"
SQ SEQUENCE 173 AA; 20055 MW; CBBCE9456F71AE7A CRC64;
MPMKGRFPIR RTLQYLSQGD VVFKDSVKVM TVNYNTHGEL GEGARKFVFF NIPQIQYKNP
WVQIMLFKNM TPTPFLRFYL DSGEQVLVDV ETKSNKEIME HVKKILGKNE ETLRRERQER
EQLSHPAHFG PRKYCLRECI CEVEGQVPCP AVVPLPRELT GKFQAALRAG AQD
