ID   RT25_DROME              Reviewed;         167 AA.
AC   Q9VY28; A0JQ26; Q29QE8;
DT   27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 132.
DE   RecName: Full=Probable 28S ribosomal protein S25, mitochondrial;
DE            Short=MRP-S25;
DE            Short=S25mt;
GN   Name=mRpS25; ORFNames=CG14413;
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley;
RX   PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA   Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA   Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA   George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA   Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA   Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA   Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA   An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA   Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA   Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA   Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA   Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA   Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA   Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA   Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA   Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA   Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA   Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA   Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA   Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA   Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA   Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA   McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA   Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA   Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA   Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA   Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA   Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA   Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA   Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA   Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA   Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA   Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA   Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA   Venter J.C.;
RT   "The genome sequence of Drosophila melanogaster.";
RL   Science 287:2185-2195(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=Berkeley;
RX   PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA   Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA   Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA   Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA   Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA   Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA   Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT   "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT   review.";
RL   Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Berkeley;
RA   Stapleton M., Carlson J.W., Chavez C., Frise E., George R.A., Kapadia B.,
RA   Pacleb J.M., Park S., Wan K.H., Yu C., Celniker S.E.;
RL   Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Component of the mitochondrial ribosome small subunit (28S)
CC       which comprises a 12S rRNA and about 30 distinct proteins.
CC       {ECO:0000250|UniProtKB:P82669}.
CC   -!- INTERACTION:
CC       Q9VY28; Q9NFP5: Sh3beta; NbExp=2; IntAct=EBI-3429710, EBI-3431675;
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:P82669}.
CC   -!- SIMILARITY: Belongs to the mitochondrion-specific ribosomal protein
CC       mS25 family. {ECO:0000305}.
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DR   EMBL; AE014298; AAF48377.1; -; Genomic_DNA.
DR   EMBL; BT024442; ABC86504.1; -; mRNA.
DR   EMBL; BT029396; ABK56982.1; -; mRNA.
DR   RefSeq; NP_511153.1; NM_078598.2.
DR   AlphaFoldDB; Q9VY28; -.
DR   SMR; Q9VY28; -.
DR   IntAct; Q9VY28; 13.
DR   STRING; 7227.FBpp0073762; -.
DR   PaxDb; Q9VY28; -.
DR   PRIDE; Q9VY28; -.
DR   DNASU; 32395; -.
DR   EnsemblMetazoa; FBtr0073945; FBpp0073762; FBgn0030572.
DR   GeneID; 32395; -.
DR   KEGG; dme:Dmel_CG14413; -.
DR   CTD; 64432; -.
DR   FlyBase; FBgn0030572; mRpS25.
DR   VEuPathDB; VectorBase:FBgn0030572; -.
DR   eggNOG; KOG4079; Eukaryota.
DR   GeneTree; ENSGT00640000091558; -.
DR   HOGENOM; CLU_094727_0_0_1; -.
DR   InParanoid; Q9VY28; -.
DR   OMA; QIMLFRN; -.
DR   OrthoDB; 1438394at2759; -.
DR   PhylomeDB; Q9VY28; -.
DR   Reactome; R-DME-5389840; Mitochondrial translation elongation.
DR   Reactome; R-DME-5419276; Mitochondrial translation termination.
DR   BioGRID-ORCS; 32395; 1 hit in 1 CRISPR screen.
DR   GenomeRNAi; 32395; -.
DR   PRO; PR:Q9VY28; -.
DR   Proteomes; UP000000803; Chromosome X.
DR   Bgee; FBgn0030572; Expressed in mouthpart and 26 other tissues.
DR   Genevisible; Q9VY28; DM.
DR   GO; GO:0005763; C:mitochondrial small ribosomal subunit; ISS:UniProtKB.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0032543; P:mitochondrial translation; TAS:FlyBase.
DR   InterPro; IPR040049; MRPS25.
DR   InterPro; IPR007741; Ribosome/NADH_DH.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   PANTHER; PTHR13274; PTHR13274; 1.
DR   Pfam; PF05047; L51_S25_CI-B8; 1.
DR   SMART; SM00916; L51_S25_CI-B8; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
PE   1: Evidence at protein level;
KW   Mitochondrion; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..167
FT                   /note="Probable 28S ribosomal protein S25, mitochondrial"
FT                   /id="PRO_0000087711"
SQ   SEQUENCE   167 AA;  19157 MW;  D5D352DEF1B11E32 CRC64;
     MPFMKGREPI RRTLKYLNAG KLVLKDKVRI FSVNYNTYGA HHAGARDFVF WNIPQIQFKN
     PEVQVLTLKN MTPSPFVRCY FDDGRDMLID LDSRNRNDII DHLVKVVGKT REQLDAEERL
     KESKDNPANF GYGCGRHCIC EIPGQVPCPG TVPLPDHMRG KILFAPK