BCP1A_MEDTR
ID BCP1A_MEDTR Reviewed; 161 AA.
AC G7L0H3;
DT 17-JUN-2020, integrated into UniProtKB/Swiss-Prot.
DT 25-JAN-2012, sequence version 1.
DT 03-AUG-2022, entry version 61.
DE RecName: Full=Blue copper protein 1a {ECO:0000303|PubMed:20687807};
DE Short=MtBcp1a {ECO:0000303|PubMed:20687807};
DE Flags: Precursor;
GN OrderedLocusNames=MTR_7g086140 {ECO:0000312|EMBL:AES80881.1};
GN ORFNames=MtrunA17_Chr7g0253671 {ECO:0000312|EMBL:RHN47499.1};
GN and
GN Name=BCP1A {ECO:0000303|PubMed:20687807};
GN Synonyms=MtC30378 {ECO:0000303|PubMed:20687807};
GN OrderedLocusNames=MTR_7g086190 {ECO:0000312|EMBL:AES80885.1};
GN ORFNames=MtrunA17_Chr7g0253701 {ECO:0000312|EMBL:RHN47502.1};
OS Medicago truncatula (Barrel medic) (Medicago tribuloides).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Trifolieae; Medicago.
OX NCBI_TaxID=3880;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Jemalong A17;
RX PubMed=22089132; DOI=10.1038/nature10625;
RA Young N.D., Debelle F., Oldroyd G.E.D., Geurts R., Cannon S.B.,
RA Udvardi M.K., Benedito V.A., Mayer K.F.X., Gouzy J., Schoof H.,
RA Van de Peer Y., Proost S., Cook D.R., Meyers B.C., Spannagl M., Cheung F.,
RA De Mita S., Krishnakumar V., Gundlach H., Zhou S., Mudge J., Bharti A.K.,
RA Murray J.D., Naoumkina M.A., Rosen B., Silverstein K.A.T., Tang H.,
RA Rombauts S., Zhao P.X., Zhou P., Barbe V., Bardou P., Bechner M.,
RA Bellec A., Berger A., Berges H., Bidwell S., Bisseling T., Choisne N.,
RA Couloux A., Denny R., Deshpande S., Dai X., Doyle J.J., Dudez A.-M.,
RA Farmer A.D., Fouteau S., Franken C., Gibelin C., Gish J., Goldstein S.,
RA Gonzalez A.J., Green P.J., Hallab A., Hartog M., Hua A., Humphray S.J.,
RA Jeong D.-H., Jing Y., Jocker A., Kenton S.M., Kim D.-J., Klee K., Lai H.,
RA Lang C., Lin S., Macmil S.L., Magdelenat G., Matthews L., McCorrison J.,
RA Monaghan E.L., Mun J.-H., Najar F.Z., Nicholson C., Noirot C.,
RA O'Bleness M., Paule C.R., Poulain J., Prion F., Qin B., Qu C., Retzel E.F.,
RA Riddle C., Sallet E., Samain S., Samson N., Sanders I., Saurat O.,
RA Scarpelli C., Schiex T., Segurens B., Severin A.J., Sherrier D.J., Shi R.,
RA Sims S., Singer S.R., Sinharoy S., Sterck L., Viollet A., Wang B.-B.,
RA Wang K., Wang M., Wang X., Warfsmann J., Weissenbach J., White D.D.,
RA White J.D., Wiley G.B., Wincker P., Xing Y., Yang L., Yao Z., Ying F.,
RA Zhai J., Zhou L., Zuber A., Denarie J., Dixon R.A., May G.D.,
RA Schwartz D.C., Rogers J., Quetier F., Town C.D., Roe B.A.;
RT "The Medicago genome provides insight into the evolution of rhizobial
RT symbioses.";
RL Nature 480:520-524(2011).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Jemalong A17;
RX PubMed=24767513; DOI=10.1186/1471-2164-15-312;
RA Tang H., Krishnakumar V., Bidwell S., Rosen B., Chan A., Zhou S.,
RA Gentzbittel L., Childs K.L., Yandell M., Gundlach H., Mayer K.F.,
RA Schwartz D.C., Town C.D.;
RT "An improved genome release (version Mt4.0) for the model legume Medicago
RT truncatula.";
RL BMC Genomics 15:312-312(2014).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Jemalong A17;
RX PubMed=30397259; DOI=10.1038/s41477-018-0286-7;
RA Pecrix Y., Staton S.E., Sallet E., Lelandais-Briere C., Moreau S.,
RA Carrere S., Blein T., Jardinaud M.F., Latrasse D., Zouine M., Zahm M.,
RA Kreplak J., Mayjonade B., Satge C., Perez M., Cauet S., Marande W.,
RA Chantry-Darmon C., Lopez-Roques C., Bouchez O., Berard A., Debelle F.,
RA Munos S., Bendahmane A., Berges H., Niebel A., Buitink J., Frugier F.,
RA Benhamed M., Crespi M., Gouzy J., Gamas P.;
RT "Whole-genome landscape of Medicago truncatula symbiotic genes.";
RL Nat. Plants 4:1017-1025(2018).
RN [4]
RP INDUCTION BY GLOMUS INTRARADICES.
RC STRAIN=cv. Jemalong J5;
RX PubMed=20687807; DOI=10.1094/mpmi-23-9-1175;
RA Paradi I., van Tuinen D., Morandi D., Ochatt S., Robert F., Jacas L.,
RA Dumas-Gaudot E.;
RT "Transcription of two blue copper-binding protein isogenes is highly
RT correlated with arbuscular mycorrhizal development in Medicago
RT truncatula.";
RL Mol. Plant Microbe Interact. 23:1175-1183(2010).
RN [5]
RP INDUCTION BY RAM1 AND GLOMUS VERSIFORME.
RX PubMed=26511916; DOI=10.1104/pp.15.01155;
RA Park H.-J., Floss D.S., Levesque-Tremblay V., Bravo A., Harrison M.J.;
RT "Hyphal branching during arbuscule development requires reduced arbuscular
RT mycorrhiza1.";
RL Plant Physiol. 169:2774-2788(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Single-pass type I
CC membrane protein {ECO:0000255}.
CC -!- INDUCTION: Accumulates in roots, in a RAM1-dependent manner, during
CC colonization by arbuscular mycorrhizal (AM) fungi (e.g. Glomus
CC versiforme and G.intraradices); the expression level correlates tightly
CC with AM development. {ECO:0000269|PubMed:20687807,
CC ECO:0000269|PubMed:26511916}.
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DR EMBL; CM001223; AES80881.1; -; Genomic_DNA.
DR EMBL; CM001223; AES80885.1; -; Genomic_DNA.
DR EMBL; PSQE01000007; RHN47499.1; -; Genomic_DNA.
DR EMBL; PSQE01000007; RHN47502.1; -; Genomic_DNA.
DR RefSeq; XP_003624663.1; XM_003624615.1.
DR RefSeq; XP_003624667.1; XM_003624619.2.
DR AlphaFoldDB; G7L0H3; -.
DR SMR; G7L0H3; -.
DR STRING; 3880.AES80881; -.
DR EnsemblPlants; AES80881; AES80881; MTR_7g086140.
DR EnsemblPlants; AES80885; AES80885; MTR_7g086190.
DR GeneID; 11427104; -.
DR GeneID; 11437278; -.
DR Gramene; AES80881; AES80881; MTR_7g086140.
DR Gramene; AES80885; AES80885; MTR_7g086190.
DR KEGG; mtr:MTR_7g086140; -.
DR KEGG; mtr:MTR_7g086190; -.
DR eggNOG; ENOG502S3NY; Eukaryota.
DR HOGENOM; CLU_058719_4_0_1; -.
DR OMA; DFNYTTW; -.
DR OrthoDB; 1537588at2759; -.
DR Proteomes; UP000002051; Chromosome 7.
DR Proteomes; UP000265566; Chromosome 7.
DR GO; GO:0046658; C:anchored component of plasma membrane; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0009610; P:response to symbiotic fungus; IEP:UniProtKB.
DR Gene3D; 2.60.40.420; -; 1.
DR InterPro; IPR008972; Cupredoxin.
DR InterPro; IPR039391; Phytocyanin.
DR InterPro; IPR003245; Phytocyanin_dom.
DR PANTHER; PTHR33021; PTHR33021; 1.
DR Pfam; PF02298; Cu_bind_like; 1.
DR SUPFAM; SSF49503; SSF49503; 1.
DR PROSITE; PS51485; PHYTOCYANIN; 1.
PE 2: Evidence at transcript level;
KW Copper; Disulfide bond; Electron transport; Glycoprotein; Membrane;
KW Metal-binding; Reference proteome; Signal; Transmembrane;
KW Transmembrane helix; Transport.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..161
FT /note="Blue copper protein 1a"
FT /id="PRO_5014573954"
FT TRANSMEM 141..161
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 24..124
FT /note="Phytocyanin"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00818"
FT BINDING 64
FT /ligand="Cu cation"
FT /ligand_id="ChEBI:CHEBI:23378"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00818"
FT BINDING 105
FT /ligand="Cu cation"
FT /ligand_id="ChEBI:CHEBI:23378"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00818"
FT BINDING 110
FT /ligand="Cu cation"
FT /ligand_id="ChEBI:CHEBI:23378"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00818"
FT BINDING 116
FT /ligand="Cu cation"
FT /ligand_id="ChEBI:CHEBI:23378"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00818"
FT CARBOHYD 70
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT DISULFID 77..111
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00818"
SQ SEQUENCE 161 AA; 17429 MW; 8A5E1541BCDDB52C CRC64;
MASSRVVLIL SISMVLLSSV AIATDHIVGD DKGWTVDFDY TQWAQDKVFR VGDNLVFNYD
PARHNVFKVN GTLFQSCTFP PKNEALSTGK DIIQLKTEGR KWYVCGVADH CSARQMKLVI
TVLAEGAPAP SPPPSSDAHS VVSSLFGVVM AIMVAIAVIF A
