RT26_MOUSE
ID RT26_MOUSE Reviewed; 200 AA.
AC Q80ZS3;
DT 17-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=28S ribosomal protein S26, mitochondrial;
DE Short=MRP-S26;
DE Short=S26mt;
DE Flags: Precursor;
GN Name=Mrps26;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Brain, Brown adipose tissue, Heart, Kidney, Liver, Spleen, and
RC Testis;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [4]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-159, AND IDENTIFICATION BY MASS
RP SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Liver;
RX PubMed=23576753; DOI=10.1073/pnas.1302961110;
RA Rardin M.J., Newman J.C., Held J.M., Cusack M.P., Sorensen D.J., Li B.,
RA Schilling B., Mooney S.D., Kahn C.R., Verdin E., Gibson B.W.;
RT "Label-free quantitative proteomics of the lysine acetylome in mitochondria
RT identifies substrates of SIRT3 in metabolic pathways.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:6601-6606(2013).
CC -!- SUBUNIT: Component of the mitochondrial ribosome small subunit (28S)
CC which comprises a 12S rRNA and about 30 distinct proteins.
CC {ECO:0000250|UniProtKB:Q3SZ86}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q3SZ86}.
CC -!- SIMILARITY: Belongs to the mitochondrion-specific ribosomal protein
CC mS26 family. {ECO:0000305}.
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DR EMBL; AL731707; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC048517; AAH48517.1; -; mRNA.
DR CCDS; CCDS16744.1; -.
DR RefSeq; NP_997090.1; NM_207207.1.
DR AlphaFoldDB; Q80ZS3; -.
DR SMR; Q80ZS3; -.
DR BioGRID; 221177; 9.
DR ComplexPortal; CPX-5301; 28S mitochondrial small ribosomal subunit.
DR STRING; 10090.ENSMUSP00000123324; -.
DR iPTMnet; Q80ZS3; -.
DR PhosphoSitePlus; Q80ZS3; -.
DR EPD; Q80ZS3; -.
DR MaxQB; Q80ZS3; -.
DR PaxDb; Q80ZS3; -.
DR PeptideAtlas; Q80ZS3; -.
DR PRIDE; Q80ZS3; -.
DR ProteomicsDB; 256797; -.
DR Antibodypedia; 48846; 102 antibodies from 24 providers.
DR DNASU; 99045; -.
DR Ensembl; ENSMUST00000145614; ENSMUSP00000123324; ENSMUSG00000037740.
DR GeneID; 99045; -.
DR KEGG; mmu:99045; -.
DR UCSC; uc008mjf.1; mouse.
DR CTD; 64949; -.
DR MGI; MGI:1333830; Mrps26.
DR VEuPathDB; HostDB:ENSMUSG00000037740; -.
DR eggNOG; KOG4691; Eukaryota.
DR GeneTree; ENSGT00390000008453; -.
DR HOGENOM; CLU_104778_0_0_1; -.
DR InParanoid; Q80ZS3; -.
DR OMA; RKPRWLP; -.
DR OrthoDB; 1623955at2759; -.
DR PhylomeDB; Q80ZS3; -.
DR TreeFam; TF316309; -.
DR Reactome; R-MMU-5389840; Mitochondrial translation elongation.
DR Reactome; R-MMU-5419276; Mitochondrial translation termination.
DR BioGRID-ORCS; 99045; 19 hits in 75 CRISPR screens.
DR ChiTaRS; Mrps26; mouse.
DR PRO; PR:Q80ZS3; -.
DR Proteomes; UP000000589; Chromosome 2.
DR RNAct; Q80ZS3; protein.
DR Bgee; ENSMUSG00000037740; Expressed in supraoptic nucleus and 262 other tissues.
DR Genevisible; Q80ZS3; MM.
DR GO; GO:0005743; C:mitochondrial inner membrane; IC:ComplexPortal.
DR GO; GO:0005763; C:mitochondrial small ribosomal subunit; ISS:UniProtKB.
DR GO; GO:0005739; C:mitochondrion; HDA:MGI.
DR GO; GO:0005654; C:nucleoplasm; ISO:MGI.
DR GO; GO:0032543; P:mitochondrial translation; IC:ComplexPortal.
DR InterPro; IPR026140; MRPS26.
DR PANTHER; PTHR21035; PTHR21035; 1.
DR Pfam; PF14943; MRP-S26; 1.
PE 1: Evidence at protein level;
KW Acetylation; Mitochondrion; Reference proteome; Ribonucleoprotein;
KW Ribosomal protein; Transit peptide.
FT TRANSIT 1..27
FT /note="Mitochondrion"
FT /evidence="ECO:0000250"
FT CHAIN 28..200
FT /note="28S ribosomal protein S26, mitochondrial"
FT /id="PRO_0000283815"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 159
FT /note="N6-acetyllysine"
FT /evidence="ECO:0007744|PubMed:23576753"
SQ SEQUENCE 200 AA; 23444 MW; FB8D915A70967215 CRC64;
MLRALNRLAA RPETRPPTPL LLPVRGRKTR HDPPAKSKVG RVQTPPAVDP AEFFVLTERY
RQYRETVRAL RLEFTLEVRR KLHEARAGVL AERKAQQAIT EHRELMAWNR DENRRMQELR
IARLQLEAQA QEVQKAEAQA QRAQEEQAWV QLKEQEVLKL QEEAKNFITR ENLEARIEEA
LDSPKSYNWA VTKEGQVVRN
