RT28_BOVIN
ID RT28_BOVIN Reviewed; 189 AA.
AC P82928; Q2KI96;
DT 26-JUL-2002, integrated into UniProtKB/Swiss-Prot.
DT 27-JUN-2006, sequence version 2.
DT 03-AUG-2022, entry version 111.
DE RecName: Full=28S ribosomal protein S28, mitochondrial;
DE Short=MRP-S28;
DE Short=S28mt;
DE Flags: Precursor;
GN Name=MRPS28;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Heart ventricle;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP PROTEIN SEQUENCE OF 73-85, AND SUBCELLULAR LOCATION.
RX PubMed=10751423; DOI=10.1074/jbc.m909762199;
RA O'Brien T.W., Liu J., Sylvester J.E., Mougey E.B., Fischel-Ghodsian N.,
RA Thiede B., Wittmann-Liebold B., Graack H.R.;
RT "Mammalian mitochondrial ribosomal proteins (4). Amino acid sequencing,
RT characterization, and identification of corresponding gene sequences.";
RL J. Biol. Chem. 275:18153-18159(2000).
RN [3]
RP PROTEIN SEQUENCE OF 100-116, AND SUBCELLULAR LOCATION.
RC TISSUE=Liver;
RX PubMed=10938081; DOI=10.1074/jbc.m003596200;
RA Koc E.C., Burkhart W., Blackburn K., Moseley A., Koc H., Spremulli L.L.;
RT "A proteomics approach to the identification of mammalian mitochondrial
RT small subunit ribosomal proteins.";
RL J. Biol. Chem. 275:32585-32591(2000).
RN [4] {ECO:0007744|PDB:3JD5}
RP STRUCTURE BY ELECTRON MICROSCOPY (7.00 ANGSTROMS), SUBCELLULAR LOCATION,
RP AND SUBUNIT.
RX PubMed=24799711; DOI=10.1073/pnas.1401657111;
RA Kaushal P.S., Sharma M.R., Booth T.M., Haque E.M., Tung C.S.,
RA Sanbonmatsu K.Y., Spremulli L.L., Agrawal R.K.;
RT "Cryo-EM structure of the small subunit of the mammalian mitochondrial
RT ribosome.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:7284-7289(2014).
CC -!- SUBUNIT: Component of the mitochondrial ribosome small subunit (28S)
CC which comprises a 12S rRNA and about 30 distinct proteins.
CC {ECO:0000269|PubMed:24799711}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:10751423,
CC ECO:0000269|PubMed:10938081, ECO:0000269|PubMed:24799711}.
CC -!- SIMILARITY: Belongs to the bacterial ribosomal protein bS1 family.
CC {ECO:0000305}.
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DR EMBL; BC112719; AAI12720.1; -; mRNA.
DR RefSeq; NP_001039866.1; NM_001046401.1.
DR PDB; 3JD5; EM; 7.00 A; f=1-189.
DR PDB; 6NEQ; EM; 3.32 A; f=1-189.
DR PDB; 6NF8; EM; 3.48 A; f=1-189.
DR PDBsum; 3JD5; -.
DR PDBsum; 6NEQ; -.
DR PDBsum; 6NF8; -.
DR AlphaFoldDB; P82928; -.
DR SMR; P82928; -.
DR CORUM; P82928; -.
DR IntAct; P82928; 2.
DR STRING; 9913.ENSBTAP00000001718; -.
DR PaxDb; P82928; -.
DR Ensembl; ENSBTAT00000001718; ENSBTAP00000001718; ENSBTAG00000001302.
DR GeneID; 535290; -.
DR KEGG; bta:535290; -.
DR CTD; 28957; -.
DR VEuPathDB; HostDB:ENSBTAG00000001302; -.
DR VGNC; VGNC:31668; MRPS28.
DR eggNOG; KOG4078; Eukaryota.
DR GeneTree; ENSGT00390000001057; -.
DR HOGENOM; CLU_109102_2_0_1; -.
DR InParanoid; P82928; -.
DR OMA; LPEDNQT; -.
DR OrthoDB; 1566742at2759; -.
DR TreeFam; TF315097; -.
DR Proteomes; UP000009136; Chromosome 14.
DR Bgee; ENSBTAG00000001302; Expressed in tongue muscle and 105 other tissues.
DR GO; GO:0005743; C:mitochondrial inner membrane; TAS:Reactome.
DR GO; GO:0005763; C:mitochondrial small ribosomal subunit; IDA:UniProtKB.
DR GO; GO:0032543; P:mitochondrial translation; ISS:UniProtKB.
DR InterPro; IPR019375; Ribosomal_S28_mit.
DR PANTHER; PTHR13447; PTHR13447; 1.
DR Pfam; PF10246; MRP-S35; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Acetylation; Direct protein sequencing; Mitochondrion;
KW Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW Transit peptide.
FT TRANSIT 1..72
FT /note="Mitochondrion"
FT /evidence="ECO:0000269|PubMed:10751423"
FT CHAIN 73..189
FT /note="28S ribosomal protein S28, mitochondrial"
FT /id="PRO_0000087713"
FT REGION 30..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..47
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 74
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9CY16"
FT MOD_RES 134
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000250|UniProtKB:Q9Y2Q9"
FT CONFLICT 100
FT /note="I -> L (in Ref. 3; AA sequence)"
FT /evidence="ECO:0000305"
FT HELIX 81..86
FT /evidence="ECO:0007829|PDB:6NEQ"
FT HELIX 89..93
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 97..115
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 118..121
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 123..126
FT /evidence="ECO:0007829|PDB:6NEQ"
FT TURN 130..134
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 140..149
FT /evidence="ECO:0007829|PDB:6NEQ"
FT STRAND 166..173
FT /evidence="ECO:0007829|PDB:6NF8"
SQ SEQUENCE 189 AA; 21041 MW; 2BA7AD808EA440C4 CRC64;
MAALCRTRAV TAESHFLRVF LFSRSCRGAG TESGSGSESS NSTEPRPRPG GFASALERHS
ELQRKAELAR TRGSPKNVES FASMLRHSPL TQMGPAKDKI VIGRIFHIVE NDLYIDFGGK
FHCVCKRPEV DGEKYQKGTR VRLRLLDLEL TSRFLGATTD TTILEAEAVL LGLQESKDSK
SKEERRENK
