RT30_MOUSE
ID RT30_MOUSE Reviewed; 442 AA.
AC Q9D0G0; B2KF79; Q3U9U4; Q9CYS8; Q9JJQ2;
DT 19-OCT-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 132.
DE RecName: Full=28S ribosomal protein S30, mitochondrial;
DE Short=MRP-S30;
DE Short=S30mt;
GN Name=Mrps30;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Bone marrow, and Embryo;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=FVB/N; TISSUE=Mammary gland;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 283-442.
RG The European IMAGE consortium;
RL Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Brain, Brown adipose tissue, Heart, Kidney, Liver, Spleen, and
RC Testis;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC -!- SUBUNIT: Component of the mitochondrial ribosome small subunit (28S)
CC which comprises a 12S rRNA and about 30 distinct proteins.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the mitochondrion-specific ribosomal protein
CC mL65 family. {ECO:0000305}.
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DR EMBL; AK011476; BAB27644.1; -; mRNA.
DR EMBL; AK151642; BAE30572.1; -; mRNA.
DR EMBL; CT030257; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC029784; AAH29784.1; -; mRNA.
DR EMBL; AL355719; CAB90812.1; -; mRNA.
DR CCDS; CCDS26794.1; -.
DR RefSeq; NP_067531.1; NM_021556.3.
DR AlphaFoldDB; Q9D0G0; -.
DR SMR; Q9D0G0; -.
DR BioGRID; 208517; 25.
DR ComplexPortal; CPX-5302; 39S mitochondrial large ribosomal subunit.
DR STRING; 10090.ENSMUSP00000022245; -.
DR iPTMnet; Q9D0G0; -.
DR PhosphoSitePlus; Q9D0G0; -.
DR SwissPalm; Q9D0G0; -.
DR EPD; Q9D0G0; -.
DR MaxQB; Q9D0G0; -.
DR PaxDb; Q9D0G0; -.
DR PeptideAtlas; Q9D0G0; -.
DR PRIDE; Q9D0G0; -.
DR ProteomicsDB; 257048; -.
DR Antibodypedia; 10864; 138 antibodies from 22 providers.
DR Ensembl; ENSMUST00000022245; ENSMUSP00000022245; ENSMUSG00000021731.
DR GeneID; 59054; -.
DR KEGG; mmu:59054; -.
DR UCSC; uc007ryr.1; mouse.
DR CTD; 10884; -.
DR MGI; MGI:1926237; Mrps30.
DR VEuPathDB; HostDB:ENSMUSG00000021731; -.
DR eggNOG; KOG4461; Eukaryota.
DR GeneTree; ENSGT00390000001442; -.
DR HOGENOM; CLU_049608_0_0_1; -.
DR InParanoid; Q9D0G0; -.
DR OMA; ITDGHFF; -.
DR OrthoDB; 514288at2759; -.
DR PhylomeDB; Q9D0G0; -.
DR TreeFam; TF320686; -.
DR Reactome; R-MMU-5389840; Mitochondrial translation elongation.
DR Reactome; R-MMU-5419276; Mitochondrial translation termination.
DR BioGRID-ORCS; 59054; 25 hits in 75 CRISPR screens.
DR ChiTaRS; Mrps30; mouse.
DR PRO; PR:Q9D0G0; -.
DR Proteomes; UP000000589; Chromosome 13.
DR RNAct; Q9D0G0; protein.
DR Bgee; ENSMUSG00000021731; Expressed in interventricular septum and 260 other tissues.
DR Genevisible; Q9D0G0; MM.
DR GO; GO:0005743; C:mitochondrial inner membrane; IC:ComplexPortal.
DR GO; GO:0005762; C:mitochondrial large ribosomal subunit; ISO:MGI.
DR GO; GO:0005739; C:mitochondrion; HDA:MGI.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0032543; P:mitochondrial translation; IC:ComplexPortal.
DR InterPro; IPR039982; MRPS30.
DR InterPro; IPR010793; Ribosomal_L37/S30.
DR PANTHER; PTHR13014; PTHR13014; 1.
DR Pfam; PF07147; PDCD9; 1.
PE 1: Evidence at protein level;
KW Mitochondrion; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT CHAIN 1..442
FT /note="28S ribosomal protein S30, mitochondrial"
FT /id="PRO_0000087721"
FT CONFLICT 121
FT /note="A -> T (in Ref. 3; AAH29784)"
FT /evidence="ECO:0000305"
FT CONFLICT 127
FT /note="P -> SPS (in Ref. 3; AAH29784)"
FT /evidence="ECO:0000305"
FT CONFLICT 155..157
FT /note="RPR -> QPG (in Ref. 3; AAH29784)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 442 AA; 49939 MW; C35A540D3A524BCC CRC64;
MAAARYWKLV PRGRGLSQNA AAKASATAPE VRDLEVVATP VARYPPIVAS MTADSKAARQ
RRVQRWQATV HAAPSVDEKI RILTKMQFKK YVVHPQISAL NADRWYQSFT KTVFVSGLPP
APALSPPPPS LDLAALRAAV CDCILQEQVY VRRRRPRSLF DRRQALASSI LDQVVRTLVN
LLAPLNPVLS TAALDCKRSV DFYWLRGEER IPAGHRKGHI DALRYQINDK PHNQIRISKQ
LPEFVPLDYS IPTEIPVMKC KPDKLPLFRR QYENSIFTGS KTADPCCYGH TQFHLIPDRL
KRERLIRQNQ AEQVEAVFRA NAIASLFAWT GAQAMYQGFW SEADVTRPFV SQAVITDGKY
FSFFCYQLNT LALTVQADQN NPRKNLCWGS QSQPLYETVE DNDVKGFDDG TLLQIVHFLL
NKPREDGAQL LASQEKELDL GP
