RT33_MOUSE
ID RT33_MOUSE Reviewed; 106 AA.
AC Q9D2R8; O88743;
DT 19-OCT-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 119.
DE RecName: Full=28S ribosomal protein S33, mitochondrial;
DE Short=MRP-S33;
DE Short=S33mt;
DE AltName: Full=Ganglioside-induced differentiation-associated-protein 3;
GN Name=Mrps33; Synonyms=Gdap3;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=ICR; TISSUE=Brain;
RX PubMed=10217254; DOI=10.1046/j.1471-4159.1999.0721781.x;
RA Liu H., Nakagawa T., Kanematsu T., Uchida T., Tsuji S.;
RT "Isolation of 10 differentially expressed cDNAs in differentiated Neuro2a
RT cells induced through controlled expression of the GD3 synthase gene.";
RL J. Neurochem. 72:1781-1790(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Pancreas;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Brain, Brown adipose tissue, Heart, and Kidney;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC -!- SUBUNIT: Component of the mitochondrial ribosome small subunit (28S)
CC which comprises a 12S rRNA and about 30 distinct proteins.
CC {ECO:0000250|UniProtKB:P82926}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q9Y291}.
CC -!- SIMILARITY: Belongs to the mitochondrion-specific ribosomal protein
CC mS33 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA76895.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; Y17852; CAA76895.1; ALT_INIT; mRNA.
DR EMBL; AK019000; BAB31503.1; -; mRNA.
DR CCDS; CCDS20026.1; -.
DR RefSeq; NP_034400.1; NM_010270.2.
DR AlphaFoldDB; Q9D2R8; -.
DR SMR; Q9D2R8; -.
DR ComplexPortal; CPX-5301; 28S mitochondrial small ribosomal subunit.
DR STRING; 10090.ENSMUSP00000031978; -.
DR iPTMnet; Q9D2R8; -.
DR PhosphoSitePlus; Q9D2R8; -.
DR EPD; Q9D2R8; -.
DR MaxQB; Q9D2R8; -.
DR PaxDb; Q9D2R8; -.
DR PRIDE; Q9D2R8; -.
DR ProteomicsDB; 260943; -.
DR Antibodypedia; 32470; 117 antibodies from 21 providers.
DR DNASU; 14548; -.
DR Ensembl; ENSMUST00000031978; ENSMUSP00000031978; ENSMUSG00000029918.
DR GeneID; 14548; -.
DR KEGG; mmu:14548; -.
DR UCSC; uc009bmi.2; mouse.
DR CTD; 51650; -.
DR MGI; MGI:1338046; Mrps33.
DR VEuPathDB; HostDB:ENSMUSG00000029918; -.
DR eggNOG; KOG4104; Eukaryota.
DR GeneTree; ENSGT00390000011401; -.
DR HOGENOM; CLU_162208_2_0_1; -.
DR InParanoid; Q9D2R8; -.
DR OMA; EVYSWYP; -.
DR OrthoDB; 1612570at2759; -.
DR PhylomeDB; Q9D2R8; -.
DR TreeFam; TF313928; -.
DR Reactome; R-MMU-5389840; Mitochondrial translation elongation.
DR Reactome; R-MMU-5419276; Mitochondrial translation termination.
DR BioGRID-ORCS; 14548; 14 hits in 75 CRISPR screens.
DR ChiTaRS; Mrps33; mouse.
DR PRO; PR:Q9D2R8; -.
DR Proteomes; UP000000589; Chromosome 6.
DR RNAct; Q9D2R8; protein.
DR Bgee; ENSMUSG00000029918; Expressed in primary oocyte and 65 other tissues.
DR ExpressionAtlas; Q9D2R8; baseline and differential.
DR Genevisible; Q9D2R8; MM.
DR GO; GO:0005743; C:mitochondrial inner membrane; IC:ComplexPortal.
DR GO; GO:0005763; C:mitochondrial small ribosomal subunit; ISS:UniProtKB.
DR GO; GO:0005739; C:mitochondrion; HDA:MGI.
DR GO; GO:0032543; P:mitochondrial translation; IC:ComplexPortal.
DR InterPro; IPR013219; Ribosomal_S27/S33_mit.
DR PANTHER; PTHR13362; PTHR13362; 1.
DR Pfam; PF08293; MRP-S33; 1.
PE 1: Evidence at protein level;
KW Acetylation; Mitochondrion; Reference proteome; Ribonucleoprotein;
KW Ribosomal protein.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250|UniProtKB:Q9Y291"
FT CHAIN 2..106
FT /note="28S ribosomal protein S33, mitochondrial"
FT /id="PRO_0000087728"
FT REGION 81..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..106
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 2
FT /note="N-acetylserine"
FT /evidence="ECO:0000250|UniProtKB:Q9Y291"
FT CONFLICT 13
FT /note="R -> L (in Ref. 1; CAA76895)"
FT /evidence="ECO:0000305"
FT CONFLICT 96
FT /note="K -> R (in Ref. 1; CAA76895)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 106 AA; 12459 MW; 3E2FFA322A0750FB CRC64;
MSPLSEYALR MSRLSARIFG EVARSTDSKS MKVVSLFSEQ PLAKKKETYD WYPNHNTYFA
LMGNLRFLGL YRDEHQDFKD EQRRLKKLRG KGKPRKGEGK RATKKK
