RT35_MOUSE
ID RT35_MOUSE Reviewed; 320 AA.
AC Q8BJZ4; B2KFS5; Q8VCG7;
DT 07-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT 07-FEB-2006, sequence version 2.
DT 25-MAY-2022, entry version 115.
DE RecName: Full=28S ribosomal protein S35, mitochondrial;
DE Short=MRP-S35;
DE Short=S35mt;
DE Flags: Precursor;
GN Name=Mrps35 {ECO:0000312|MGI:MGI:2385255};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1] {ECO:0000312|EMBL:BAC36950.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J {ECO:0000312|EMBL:BAC36950.1}, and
RC NOD {ECO:0000312|EMBL:BAE41824.1};
RC TISSUE=Embryo {ECO:0000312|EMBL:BAC36950.1};
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3] {ECO:0000305, ECO:0000312|EMBL:AAH19964.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 4-320.
RC STRAIN=FVB/N {ECO:0000312|EMBL:AAH19964.1};
RC TISSUE=Liver {ECO:0000312|EMBL:AAH19964.1};
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Brain, Brown adipose tissue, Heart, Kidney, Liver, Lung, Spleen, and
RC Testis;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC -!- SUBUNIT: Component of the mitochondrial ribosome small subunit (28S)
CC which comprises a 12S rRNA and about 30 distinct proteins.
CC {ECO:0000250|UniProtKB:Q2YDF6}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q2YDF6}.
CC -!- SIMILARITY: Belongs to the mitochondrion-specific ribosomal protein
CC mS35 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAH19964.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AK077677; BAC36950.1; -; mRNA.
DR EMBL; AK170480; BAE41824.1; -; mRNA.
DR EMBL; CU207396; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC019964; AAH19964.1; ALT_INIT; mRNA.
DR CCDS; CCDS51959.1; -.
DR RefSeq; NP_663548.2; NM_145573.2.
DR AlphaFoldDB; Q8BJZ4; -.
DR SMR; Q8BJZ4; -.
DR BioGRID; 231269; 5.
DR ComplexPortal; CPX-5301; 28S mitochondrial small ribosomal subunit.
DR IntAct; Q8BJZ4; 1.
DR STRING; 10090.ENSMUSP00000048348; -.
DR iPTMnet; Q8BJZ4; -.
DR PhosphoSitePlus; Q8BJZ4; -.
DR EPD; Q8BJZ4; -.
DR MaxQB; Q8BJZ4; -.
DR PaxDb; Q8BJZ4; -.
DR PeptideAtlas; Q8BJZ4; -.
DR PRIDE; Q8BJZ4; -.
DR ProteomicsDB; 257049; -.
DR DNASU; 232536; -.
DR GeneID; 232536; -.
DR KEGG; mmu:232536; -.
DR UCSC; uc009ess.1; mouse.
DR CTD; 60488; -.
DR MGI; MGI:2385255; Mrps35.
DR eggNOG; KOG3933; Eukaryota.
DR InParanoid; Q8BJZ4; -.
DR OrthoDB; 1339087at2759; -.
DR PhylomeDB; Q8BJZ4; -.
DR TreeFam; TF318686; -.
DR Reactome; R-MMU-5389840; Mitochondrial translation elongation.
DR Reactome; R-MMU-5419276; Mitochondrial translation termination.
DR BioGRID-ORCS; 232536; 23 hits in 109 CRISPR screens.
DR ChiTaRS; Mrps35; mouse.
DR PRO; PR:Q8BJZ4; -.
DR Proteomes; UP000000589; Unplaced.
DR RNAct; Q8BJZ4; protein.
DR GO; GO:0005743; C:mitochondrial inner membrane; IC:ComplexPortal.
DR GO; GO:0005763; C:mitochondrial small ribosomal subunit; ISS:UniProtKB.
DR GO; GO:0005739; C:mitochondrion; HDA:MGI.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0032543; P:mitochondrial translation; IC:ComplexPortal.
DR InterPro; IPR039848; Ribosomal_S24/S35.
DR InterPro; IPR019349; Ribosomal_S24/S35_mit.
DR PANTHER; PTHR13490; PTHR13490; 1.
DR Pfam; PF10213; MRP-S28; 1.
PE 1: Evidence at protein level;
KW Mitochondrion; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW Transit peptide.
FT TRANSIT 1..?
FT /note="Mitochondrion"
FT /evidence="ECO:0000305"
FT CHAIN ?..320
FT /note="28S ribosomal protein S35, mitochondrial"
FT /id="PRO_0000046056"
FT REGION 24..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..60
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 11
FT /note="S -> T (in Ref. 1; BAC36950/BAE41824)"
FT /evidence="ECO:0000305"
FT CONFLICT 16
FT /note="P -> A (in Ref. 1; BAC36950/BAE41824)"
FT /evidence="ECO:0000305"
FT CONFLICT 216
FT /note="Y -> C (in Ref. 1; BAC36950/BAE41824)"
FT /evidence="ECO:0000305"
FT CONFLICT 293
FT /note="V -> I (in Ref. 1; BAC36950/BAE41824)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 320 AA; 35975 MW; 83A35D706DFB806E CRC64;
MAAAALQLRQ SLCPGPRVLR TFSSVASPAA PRAGPRTASR SERPMRRKAL PPRTEKMDTD
QDWPSVYPTA APFKPSAVPL PVRMGYPVKK GVPMAKEGNL ELLKIPNFLH LTPVAIKRHC
AALKDFCTEW PAALDSDEKC EEHFPVEIDT ADYVSSGPSI RNPKARAVTL RVKLSSLNLD
NHAKKKLIKL VGERYCKATD VLTITTDRCP LKRQNYDYAV YLLTVLYHES WKTEDWENSK
TEEDMDEYVW AKSSSENSVL QTLLQMRAAE SSVAPSREEL LGTKEVEDYQ KCVVRLKNEG
ENEASLAQYK ESVKRLLNLA
