ID   RTBDN_ICTTR             Reviewed;         254 AA.
AC   Q5DRQ5;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   29-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Retbindin;
DE   Flags: Precursor;
GN   Name=RTBDN;
OS   Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus
OS   tridecemlineatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae;
OC   Xerinae; Marmotini; Ictidomys.
OX   NCBI_TaxID=43179;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Yan W., Wang C., Zack D.;
RT   "Molecular cloning and characterization of retinal-enriched genes in the
RT   13-lined ground squirrel, a cone dominant mammalian animal model.";
RL   Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Riboflavin-binding protein which might have a role in retinal
CC       flavin transport. {ECO:0000250|UniProtKB:Q8QZY4}.
CC   -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC       matrix, interphotoreceptor matrix {ECO:0000250|UniProtKB:Q8QZY4}. Cell
CC       membrane; Peripheral membrane protein {ECO:0000250|UniProtKB:Q8QZY4}.
CC   -!- PTM: Not N-glycosylated. {ECO:0000250|UniProtKB:Q8QZY4}.
CC   -!- SIMILARITY: Belongs to the folate receptor family. {ECO:0000305}.
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DR   EMBL; AY517477; AAS89815.1; -; mRNA.
DR   RefSeq; NP_001269190.1; NM_001282261.1.
DR   AlphaFoldDB; Q5DRQ5; -.
DR   STRING; 43179.ENSSTOP00000005560; -.
DR   GeneID; 101959854; -.
DR   CTD; 83546; -.
DR   eggNOG; ENOG502RYYP; Eukaryota.
DR   InParanoid; Q5DRQ5; -.
DR   OrthoDB; 1534387at2759; -.
DR   Proteomes; UP000005215; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0033165; C:interphotoreceptor matrix; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR004269; Folate_rcpt.
DR   InterPro; IPR018143; Folate_rcpt-like.
DR   PANTHER; PTHR10517; PTHR10517; 1.
DR   Pfam; PF03024; Folate_rec; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Disulfide bond; Extracellular matrix; Membrane;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000255"
FT   CHAIN           30..254
FT                   /note="Retbindin"
FT                   /id="PRO_0000043176"
FT   REGION          227..254
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   DISULFID        104..174
FT                   /evidence="ECO:0000250|UniProtKB:P15328"
FT   DISULFID        111..151
FT                   /evidence="ECO:0000250|UniProtKB:P15328"
FT   DISULFID        144..188
FT                   /evidence="ECO:0000250|UniProtKB:P15328"
FT   DISULFID        157..170
FT                   /evidence="ECO:0000250|UniProtKB:P15328"
SQ   SEQUENCE   254 AA;  27236 MW;  A3C00F45D3571390 CRC64;
     MACRSHIQPS DLACTMQLAL AWIILGACGG SHQFQARSQG HLGLASNLGT NQVQLAGDLQ
     ASGPQPYMMI QDPDSQAFPL PEPCCPSEMD TPETSGPGIF PPRCRTPSSG CESFLGHLQR
     ALRNRFHLLL LGVRQAPPLC EELCQNWFAT CEADITCGRT WLWPSGKRSC EGRCRTYGQT
     FADGVDLCRS VLGHILPVAA PGSRHCLNIS ISLLPRPRPG RWARETISQR SRRRGTGILD
     AGGSGSGSGS GSGP