RTC4_ASHGO
ID RTC4_ASHGO Reviewed; 407 AA.
AC Q752E4;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 05-OCT-2010, sequence version 2.
DT 25-MAY-2022, entry version 65.
DE RecName: Full=Restriction of telomere capping protein 4;
GN Name=RTC4; OrderedLocusNames=AFR632C;
OS Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS (Yeast) (Eremothecium gossypii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=284811;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=15001715; DOI=10.1126/science.1095781;
RA Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA Gaffney T.D., Philippsen P.;
RT "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT cerevisiae genome.";
RL Science 304:304-307(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=23749448; DOI=10.1534/g3.112.002881;
RA Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT loci, numerous translocations, lack of transposons, and distinct gene
RT duplications.";
RL G3 (Bethesda) 3:1225-1239(2013).
CC -!- FUNCTION: May be involved in a process influencing telomere capping.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RTC4 family. {ECO:0000305}.
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DR EMBL; AE016819; AAS54003.2; -; Genomic_DNA.
DR RefSeq; NP_986179.2; NM_212315.2.
DR AlphaFoldDB; Q752E4; -.
DR STRING; 33169.AAS54003; -.
DR EnsemblFungi; AAS54003; AAS54003; AGOS_AFR632C.
DR GeneID; 4622467; -.
DR KEGG; ago:AGOS_AFR632C; -.
DR eggNOG; ENOG502S1RG; Eukaryota.
DR HOGENOM; CLU_677876_0_0_1; -.
DR InParanoid; Q752E4; -.
DR OMA; MYYDNAR; -.
DR Proteomes; UP000000591; Chromosome VI.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR InterPro; IPR039024; RTC4.
DR InterPro; IPR028094; RTC4_C.
DR PANTHER; PTHR41391; PTHR41391; 1.
DR Pfam; PF14474; RTC4; 1.
DR SMART; SM01312; RTC4; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Nucleus; Reference proteome.
FT CHAIN 1..407
FT /note="Restriction of telomere capping protein 4"
FT /id="PRO_0000408794"
FT REGION 17..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 354..407
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..60
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 66..98
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 372..399
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 407 AA; 46602 MW; 7D3C3BFA63D0D566 CRC64;
MSHVRRKRIT AIYSTSMKDD NAMIVKSHSS KESKRDPRVE LSDNEYISND EKDSTDAKPA
ADEPQLELNC SSSLSSSDDD SSVSSSISSS SELDALSEPG LSSPNAVPLV YKVPHESSKA
IQVARRLENI HASVQKDDDY MPKLCINKSM VFTDRQDQVA EYERLLEIRL KYKNAFKVPP
TLFADQLLSK AEKYIPLVEE ILRGERPSMY YDNARKAYQK SSRALLSVEE FRQLDLKTFT
AGYFGIKRQI RLSTEILSQY QDKLSKHRNP TVQWWGPTDF SHYVLAPEIL SYVCRDELGL
ADIDEAWTYM ESTTEYGLNV ADEEPLDIWE LEYEEKKLQR LGLGPKYSSM TYRKHPARAS
AVVDTSKNGS KEHKRKGKQH KLKKGQQSTK IRVSKKRRRV QPHSICD
