ID   RTC4_KLULA              Reviewed;         376 AA.
AC   Q6CUR6;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=Restriction of telomere capping protein 4;
GN   Name=RTC4; OrderedLocusNames=KLLA0C02827g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: May be involved in a process influencing telomere capping.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RTC4 family. {ECO:0000305}.
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DR   EMBL; CR382123; CAH01174.1; -; Genomic_DNA.
DR   RefSeq; XP_452323.1; XM_452323.1.
DR   AlphaFoldDB; Q6CUR6; -.
DR   STRING; 28985.XP_452323.1; -.
DR   EnsemblFungi; CAH01174; CAH01174; KLLA0_C02827g.
DR   GeneID; 2891851; -.
DR   KEGG; kla:KLLA0_C02827g; -.
DR   eggNOG; ENOG502S1RG; Eukaryota.
DR   HOGENOM; CLU_735798_0_0_1; -.
DR   InParanoid; Q6CUR6; -.
DR   Proteomes; UP000000598; Chromosome C.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR039024; RTC4.
DR   InterPro; IPR028094; RTC4_C.
DR   PANTHER; PTHR41391; PTHR41391; 1.
DR   Pfam; PF14474; RTC4; 1.
DR   SMART; SM01312; RTC4; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..376
FT                   /note="Restriction of telomere capping protein 4"
FT                   /id="PRO_0000408796"
FT   REGION          50..81
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        50..79
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   376 AA;  42762 MW;  0DF6A3084776CB5E CRC64;
     MVSSSNASSD QLSQESLVII SSSSHEGFSY GKRHPTVALN GSLNKKLRVR SGSLEELSDS
     EFDVSAKEEE KKSTELQDPK SIDLETQFSD VESDLDSLNE RNKGADMLEL TDDESVHELP
     GSSRDFFDEN DVEEMSMELI KMYSIGLNAE GVSEFKKSSA SLVLPKNTEK STYLKSNAVR
     QKFMTKYDLP PVLFLDQLES RTREHISVCD AILTGKVSSL YYSMAKTVQK NSKRQVITNE
     ELRDLNILKF TAGYFGSRRQ AIVGMLILET YGEKLKRNKN PVISFWGPYD FSQYILAPEV
     LSYLCMDDFK LNNIEDAWDI MQTTIEFGTM VADLSPLEVY EIECEEESLR RLRLPQQYSS
     MSYRDDPRRK QDSNVG