RTC4_LACTC
ID RTC4_LACTC Reviewed; 374 AA.
AC C5DKA0;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 44.
DE RecName: Full=Restriction of telomere capping protein 4;
GN Name=RTC4; OrderedLocusNames=KLTH0F02926g;
OS Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS (Yeast) (Kluyveromyces thermotolerans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Lachancea.
OX NCBI_TaxID=559295;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284;
RX PubMed=19525356; DOI=10.1101/gr.091546.109;
RG The Genolevures Consortium;
RA Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT "Comparative genomics of protoploid Saccharomycetaceae.";
RL Genome Res. 19:1696-1709(2009).
CC -!- FUNCTION: May be involved in a process influencing telomere capping.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RTC4 family. {ECO:0000305}.
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DR EMBL; CU928170; CAR23901.1; -; Genomic_DNA.
DR RefSeq; XP_002554338.1; XM_002554292.1.
DR AlphaFoldDB; C5DKA0; -.
DR STRING; 559295.C5DKA0; -.
DR PRIDE; C5DKA0; -.
DR EnsemblFungi; CAR23901; CAR23901; KLTH0F02926g.
DR GeneID; 8292530; -.
DR KEGG; lth:KLTH0F02926g; -.
DR eggNOG; ENOG502S1RG; Eukaryota.
DR HOGENOM; CLU_739810_0_0_1; -.
DR InParanoid; C5DKA0; -.
DR OMA; ALCQEEM; -.
DR OrthoDB; 1427748at2759; -.
DR Proteomes; UP000002036; Chromosome F.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR InterPro; IPR039024; RTC4.
DR InterPro; IPR028094; RTC4_C.
DR PANTHER; PTHR41391; PTHR41391; 1.
DR Pfam; PF14474; RTC4; 1.
DR SMART; SM01312; RTC4; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Nucleus; Reference proteome.
FT CHAIN 1..374
FT /note="Restriction of telomere capping protein 4"
FT /id="PRO_0000408797"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 75..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 129..180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..27
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 164..180
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 374 AA; 42723 MW; 7FCD7AEB8220C375 CRC64;
MAPEHAHYNG SKKIRSLRED KLASGAKARS RYGEACFQRG RVIKEARGQH TALRAGKDYE
TNLRRKREFR VPLELEPGRL RVQETTPSLD SAGTDDQDSE NAESDGDLPI EVICDLEVIP
QDVDEQELQR LRRENDRSSS PAGANEGIDD EEAGEEKVSF PSPQHSKHSH GPTGSEQEHF
QRVSCVRHSY MQKLKLPQPL LAEELLERTL KYFPLVEKIL SGQHPSMYYD HARSAFKRSR
RAVLSIDEFR RLDLSLFTAG YYGVRRQMRV AVEVLHHYRD LIARQNNRVL RWWGVSDFAQ
YVLAPELLSA LCQEEMNLPT LEDAWDVMEA TTEFGLLVAD DGPLEEWEVP AHLARLEAAG
HSSNLREDPS NDKR
