ID   RTC4_VANPO              Reviewed;         388 AA.
AC   A7TF50;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 40.
DE   RecName: Full=Restriction of telomere capping protein 4;
GN   Name=RTC4; ORFNames=Kpol_2000p40;
OS   Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS   2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX   NCBI_TaxID=436907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL
RC   Y-8283 / UCD 57-17;
RX   PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA   Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT   "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT   species descended from a whole-genome duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC   -!- FUNCTION: May be involved in a process influencing telomere capping.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RTC4 family. {ECO:0000305}.
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DR   EMBL; DS480382; EDO19075.1; -; Genomic_DNA.
DR   RefSeq; XP_001646933.1; XM_001646883.1.
DR   AlphaFoldDB; A7TF50; -.
DR   STRING; 436907.A7TF50; -.
DR   EnsemblFungi; EDO19075; EDO19075; Kpol_2000p40.
DR   GeneID; 5547402; -.
DR   KEGG; vpo:Kpol_2000p40; -.
DR   eggNOG; ENOG502S1RG; Eukaryota.
DR   HOGENOM; CLU_049922_1_0_1; -.
DR   InParanoid; A7TF50; -.
DR   OrthoDB; 1468001at2759; -.
DR   PhylomeDB; A7TF50; -.
DR   Proteomes; UP000000267; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR039024; RTC4.
DR   InterPro; IPR028094; RTC4_C.
DR   PANTHER; PTHR41391; PTHR41391; 1.
DR   Pfam; PF14474; RTC4; 1.
DR   SMART; SM01312; RTC4; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..388
FT                   /note="Restriction of telomere capping protein 4"
FT                   /id="PRO_0000408798"
FT   REGION          22..58
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        22..46
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   388 AA;  44686 MW;  8DE76D6CAFD5CA18 CRC64;
     MSNKGLKRKT YGKRSLNYSI KNSKLNLNQE SSEHSSRSNT ELSDDSASSF ECEDRVQDDE
     SYTNGISNQI INAFGVLEGS NLKVEEDSVS NGENEFITTT NSEEEKIADA DDEQPLDEIE
     VVKLKDTKLH VKYGSHELKH LGLFDSILQK VPLKLHKRKK RTIIKEFTQR DFLIKKLEVR
     AKYNKEFKLP QVLYHDEIIE AIKPYMDIII QLLKGKLQSV YYDSAKQAFL NSERAILSAH
     EFRALDLKKF QAGYYGLRRQ LCVGEYIYDI YKEKICSLKS PTARWWGPRD FSSYVLAPEL
     LISVCIEEMG LKDDPNYFDD NNEGSGESAR SKAYSILQDT VKFGQIVADT DPMQPWEVLS
     EEKNIENLQL NVAKYSSRKW RIALPKET