RTC5_ASPCL
ID RTC5_ASPCL Reviewed; 642 AA.
AC A1CHC0;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 1.
DT 25-MAY-2022, entry version 50.
DE RecName: Full=Restriction of telomere capping protein 5;
GN Name=rtc5; ORFNames=ACLA_047440;
OS Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 /
OS NRRL 1 / QM 1276 / 107).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=344612;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1;
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
CC -!- FUNCTION: May be involved in a process influencing telomere capping.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RTC5 family. {ECO:0000305}.
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DR EMBL; DS027054; EAW10275.1; -; Genomic_DNA.
DR RefSeq; XP_001271701.1; XM_001271700.1.
DR AlphaFoldDB; A1CHC0; -.
DR SMR; A1CHC0; -.
DR STRING; 344612.A1CHC0; -.
DR EnsemblFungi; EAW10275; EAW10275; ACLA_047440.
DR GeneID; 4704322; -.
DR KEGG; act:ACLA_047440; -.
DR VEuPathDB; FungiDB:ACLA_047440; -.
DR eggNOG; ENOG502QV3R; Eukaryota.
DR HOGENOM; CLU_011918_1_0_1; -.
DR OMA; SHHVLTW; -.
DR OrthoDB; 714794at2759; -.
DR Proteomes; UP000006701; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR InterPro; IPR006571; TLDc_dom.
DR Pfam; PF07534; TLD; 1.
DR SMART; SM00584; TLDc; 1.
DR PROSITE; PS51886; TLDC; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Reference proteome.
FT CHAIN 1..642
FT /note="Restriction of telomere capping protein 5"
FT /id="PRO_0000408813"
FT DOMAIN 353..571
FT /note="TLDc"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01234"
FT REGION 143..186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..165
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 642 AA; 69929 MW; 2DD4E1F268E89B60 CRC64;
MGLGQSTEQA GHSPEQLSHV LAERFATKCF TPLELTHFKD NFFSRAIDQE GIKYWSEKIL
SDFLGIPDSS DSHCPLDAGP VLFRMVSYLG AFPFQNTMAP SVLTFEAMVK VVVLLTERYG
KVLRRARRDR VKLLFGSLAD VGRRGAGQPP DENADNKEED KSSTAKSHAT GFAVDDPAND
NYEDDEDDDD LVLAALESLD AIDVFKHDSR VDKTVYEARI SVATFRRLLM LLIVIAPLSS
LEPVKKYTSD LNEERMDNVR QEADSILAAF DLNKSADGIS FQSFSEIVSG SLPYLFDPLT
TLFEHLLFSK NLDLSQKRGG TETTIVADTA EEVSESPLSS PSSIMLPGSF ESTILKPSAI
SHLSFFLSSP ATDVNLLRGN MRLHPVFSTV AHGSSLTSFS HNVLTWNSGT LLLLEGAVTE
SSDRGVGTIT LGAYLPQHWK SGPLAHSPSR PFDSLSLPCL FELSPKHLLM QGNTSPSVHK
PNAPSAYFST NTGIAIGCQI PPPSRSQQFE PTPLGAGSLI IDASLESATF YASPIGHNGV
FLPSPSVSKN GSETTSKMQI DIYTLEVWGL VPDPSDETLT EPGHNAIERQ RARWDFEARE
AERRRSLNLK AGAGDSAMEG ARWLLETAGL IGDRPGRSGG SM