ID   RTC5_ASPFU              Reviewed;         642 AA.
AC   Q4WP54;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   17-APR-2007, sequence version 2.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Restriction of telomere capping protein 5;
GN   Name=rtc5; ORFNames=AFUA_4G08080;
OS   Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS   A1100) (Aspergillus fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=330879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100;
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA   Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P.,
RA   Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L.,
RA   Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N.,
RA   Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA   Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E.,
RA   Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H.,
RA   Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A.,
RA   Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L.,
RA   Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D.,
RA   O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L.,
RA   Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U.,
RA   Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M.,
RA   Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C.,
RA   Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F.,
RA   Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R.,
RA   Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N.,
RA   Barrell B.G., Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
CC   -!- FUNCTION: May be involved in a process influencing telomere capping.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RTC5 family. {ECO:0000305}.
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DR   EMBL; AAHF01000005; EAL89980.2; -; Genomic_DNA.
DR   RefSeq; XP_752018.2; XM_746925.2.
DR   AlphaFoldDB; Q4WP54; -.
DR   STRING; 330879.Q4WP54; -.
DR   EnsemblFungi; EAL89980; EAL89980; AFUA_4G08080.
DR   GeneID; 3508952; -.
DR   KEGG; afm:AFUA_4G08080; -.
DR   VEuPathDB; FungiDB:Afu4g08080; -.
DR   eggNOG; ENOG502QV3R; Eukaryota.
DR   HOGENOM; CLU_011918_1_0_1; -.
DR   InParanoid; Q4WP54; -.
DR   OMA; SHHVLTW; -.
DR   OrthoDB; 714794at2759; -.
DR   Proteomes; UP000002530; Chromosome 4.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0006979; P:response to oxidative stress; IBA:GO_Central.
DR   InterPro; IPR006571; TLDc_dom.
DR   Pfam; PF07534; TLD; 1.
DR   SMART; SM00584; TLDc; 1.
DR   PROSITE; PS51886; TLDC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..642
FT                   /note="Restriction of telomere capping protein 5"
FT                   /id="PRO_0000408816"
FT   DOMAIN          354..570
FT                   /note="TLDc"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01234"
FT   REGION          322..343
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   642 AA;  69814 MW;  345C3CA74FBF7EE9 CRC64;
     MGVGQSTELP GHVGTPEHLS HVLAERFATK CFTPLELTHF KDNFFSRAID QGGLKYWNEK
     ILSDFLGIPD SSDSHCPLDA GPVIFRMVSY LGAFPFQNTL APSVLTFEAM VKVAVLLTER
     YGRVLRRGRK DRIKLLFGSL ADVGRRNVST SPDTEDVCRE TDDTVKPHVT GFEVDAPAND
     DYGDEDEDED DDDLALAALE SLDAIDVFKH DSRVDKKVYE ARISVATLRR LLMLFLVIAP
     LKTLEPVTLY TSDLNEARME SIRKEADTIL AAFSTEDSDG GISYRSFANI TSTALPYLFD
     PLTPLFEHLL FSKNLDMTKK SRSDATVTDT IEKPSDSPGP SPSTIVLPGG FESSILKPSV
     VSHLSFFLPS PTSNANLLRG NMRLHPVFST AVHGSSLTSF SHNVLTWNAG TLLLLEGAVS
     ESSEHGEGMV TLGAYLPQPW KSAPLSHSST KPSDSSALPC LFELSPKHQL LQGNPSPSVQ
     KPNAPVAYFS TSTGIAIGCQ IPPPSRSQLL TPTPLGAGSL TVDTSLESAT FYMSSIGHNG
     VFLPPATTSM SEETVRKQID IYTMEIWGLV PDPSDTSSSD LSRQSPVELQ RAKWEFEARE
     AERRRNLNLK AGAGDPAAEG ARWLLETAGL IGDRPGQRGG SL