ID   RTC5_ASPNC              Reviewed;         644 AA.
AC   A2QI73;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   06-MAR-2007, sequence version 1.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Restriction of telomere capping protein 5;
GN   Name=rtc5; ORFNames=An04g02510;
OS   Aspergillus niger (strain CBS 513.88 / FGSC A1513).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=425011;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 513.88 / FGSC A1513 / ATCC MYA-4892;
RX   PubMed=17259976; DOI=10.1038/nbt1282;
RA   Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J.,
RA   Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R.,
RA   Bendtsen J.D., Benen J.A.E., van den Berg M., Breestraat S., Caddick M.X.,
RA   Contreras R., Cornell M., Coutinho P.M., Danchin E.G.J., Debets A.J.M.,
RA   Dekker P., van Dijck P.W.M., van Dijk A., Dijkhuizen L., Driessen A.J.M.,
RA   d'Enfert C., Geysens S., Goosen C., Groot G.S.P., de Groot P.W.J.,
RA   Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.T.W.,
RA   van den Hondel C.A.M.J.J., van der Heijden R.T.J.M., van der Kaaij R.M.,
RA   Klis F.M., Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X.,
RA   van der Maarel M.J.E.C., Meulenberg R., Menke H., Mortimer M.A.,
RA   Nielsen J., Oliver S.G., Olsthoorn M., Pal K., van Peij N.N.M.E.,
RA   Ram A.F.J., Rinas U., Roubos J.A., Sagt C.M.J., Schmoll M., Sun J.,
RA   Ussery D., Varga J., Vervecken W., van de Vondervoort P.J.J., Wedler H.,
RA   Woesten H.A.B., Zeng A.-P., van Ooyen A.J.J., Visser J., Stam H.;
RT   "Genome sequencing and analysis of the versatile cell factory Aspergillus
RT   niger CBS 513.88.";
RL   Nat. Biotechnol. 25:221-231(2007).
CC   -!- FUNCTION: May be involved in a process influencing telomere capping.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RTC5 family. {ECO:0000305}.
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DR   EMBL; AM270071; CAL00738.1; -; Genomic_DNA.
DR   AlphaFoldDB; A2QI73; -.
DR   SMR; A2QI73; -.
DR   PaxDb; A2QI73; -.
DR   EnsemblFungi; CAL00738; CAL00738; An04g02510.
DR   HOGENOM; CLU_011918_1_0_1; -.
DR   Proteomes; UP000006706; Chromosome 6L.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006571; TLDc_dom.
DR   Pfam; PF07534; TLD; 1.
DR   SMART; SM00584; TLDc; 1.
DR   PROSITE; PS51886; TLDC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..644
FT                   /note="Restriction of telomere capping protein 5"
FT                   /id="PRO_0000408817"
FT   DOMAIN          363..574
FT                   /note="TLDc"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01234"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          158..177
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          329..352
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..21
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   644 AA;  70268 MW;  75C429280E9ED9E8 CRC64;
     MGLSQSTEYG GQTSSSEKSN PVSDKTLEEL SYVLAERFAT KCFTPLELTH LKDNFFSRAI
     DQGGLKYWNE KTLSDFLGIP DSSESHCPLD AGPVIFRMVS YLGAFPFQNT LAPSVLTFEA
     MVKVVVLLTE RYGKVLRRAR RDRIRLLFGS LADVGRKSVE QHTNGDEVSE DADAPAPNSH
     VPGFAIDEPA NDDYEDEEDD DLALAALESL DAIEVFKHDS RMDRAVYEAR ISADTLRRLL
     MLLIVISPLK PLEPVKIYTS DLTEERMKAV RSEADDIMAA FNREPSGGIS YKEFARIVTS
     SFPYLFDPLT PLFEHLLFSR NLNLSQKRNR ADSTASEPVE EEAPEDDLPS PPTITLPGSF
     ESVILNSSVI SHLSFFLPSS SESLNFLRGN VRLHPVFSTV AHGSSLTSFS HHVLTWSSGT
     LLVLEGTDPT GEMLTIGAYL PQPWKSPNST QSSSKFSNSV LPCLFQLSPK HLLLQGNPSS
     TIQQQSNIPA AYFSTSSGIS IGCQIPPSSR SNQKPPTPHG AGSLTIDVSL ETAQFHVSPV
     VRNGVFLPPP PGSTPDTTVK TTIEIYNLEV WGLVPDPTTT SAEGGKSAVE LQQAKWDFEA
     QEAERRRSVN LKTGGSAAEE SARWLLETAG LIGDGAGRRA GGSV