ID   RTC5_BLAGS              Reviewed;         691 AA.
AC   C5JIS5; A0A179UGH5;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 38.
DE   RecName: Full=Restriction of telomere capping protein 5;
GN   Name=RTC5; ORFNames=BDBG_02404;
OS   Blastomyces gilchristii (strain SLH14081) (Blastomyces dermatitidis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX   NCBI_TaxID=559298;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SLH14081;
RX   PubMed=26439490; DOI=10.1371/journal.pgen.1005493;
RA   Munoz J.F., Gauthier G.M., Desjardins C.A., Gallo J.E., Holder J.,
RA   Sullivan T.D., Marty A.J., Carmen J.C., Chen Z., Ding L., Gujja S.,
RA   Magrini V., Misas E., Mitreva M., Priest M., Saif S., Whiston E.A.,
RA   Young S., Zeng Q., Goldman W.E., Mardis E.R., Taylor J.W., McEwen J.G.,
RA   Clay O.K., Klein B.S., Cuomo C.A.;
RT   "The dynamic genome and transcriptome of the human fungal pathogen
RT   Blastomyces and close relative Emmonsia.";
RL   PLoS Genet. 11:E1005493-E1005493(2015).
CC   -!- FUNCTION: May be involved in a process influencing telomere capping.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RTC5 family. {ECO:0000305}.
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DR   EMBL; GG657450; OAT06121.1; -; Genomic_DNA.
DR   RefSeq; XP_002627733.1; XM_002627687.1.
DR   AlphaFoldDB; C5JIS5; -.
DR   STRING; 559298.C5JIS5; -.
DR   EnsemblFungi; OAT06121; OAT06121; BDBG_02404.
DR   GeneID; 8506783; -.
DR   KEGG; bgh:BDBG_02404; -.
DR   VEuPathDB; FungiDB:BDBG_02404; -.
DR   HOGENOM; CLU_011918_1_0_1; -.
DR   Proteomes; UP000002038; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006571; TLDc_dom.
DR   Pfam; PF07534; TLD; 1.
DR   SMART; SM00584; TLDc; 1.
DR   PROSITE; PS51886; TLDC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..691
FT                   /note="Restriction of telomere capping protein 5"
FT                   /id="PRO_0000408808"
FT   DOMAIN          366..614
FT                   /note="TLDc"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01234"
FT   REGION          329..355
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          559..595
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        341..355
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        564..595
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   691 AA;  74307 MW;  6BAEE83737974069 CRC64;
     MGGALSTEAQ RASSVEELSQ RLAHRFATKC FTPLELTHLK DNFFSRALEQ RGIRYWNEEI
     LSDFLGIPDG AGSAATATSD GSLDAGPVIF RMVSYLGAFP FQNTMAPTVL TFEAMIKVVV
     LLTERYGKVL KRGKKDRIKL LFGSLADVGR RDIITQLKEA AEDSLESIGV ADPNGGSTFA
     HNGGFLIDQP INDGEDEDDD DDLALAALES LDAIEVFKQD QRIDKTVFES KISLTTFRRL
     LTLLIVTAPL RPLGTVSKYT TGLSKSSLDT VHEQVDSILA ALGSEVAEDG IGYKSFSELI
     STSLPYLFDP LTPLFEHLLF SKNLNLSRKS ETSNGQADKP APTPPSTPPR SPPLSPVILT
     GGFDSCILNP VILSHLSFFI STSPHIPNIF RNRTHLHPVF SSTEHGESLT SFSHHVMTWQ
     APTILLIRGA VTSENNEEQI TTIGAYIPQP WKQSSSYSSR RSSESVHPST LPCLFEIFPV
     HTVLQGSPSF SSLKSNMPVS HFSTKTGIAI GCIIPPSSRK SLGSDLHPKP AGGGSLLIDS
     ALENATFVVS DGLNGEGVFL PPGVSPSGTT TTGTTSTKTP SSTSPTASAA SVSTSNHNTT
     KSISIYNLEV WGIIPSQSLA TQSDGTGSPI EKQDAIALQR AQWNFEAREA ERRQAINMKV
     GGGESEAQTG RALLEMAGII GDSQYSAHPH H