ID   RTC5_CANTT              Reviewed;         625 AA.
AC   C5MCY0;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 39.
DE   RecName: Full=Restriction of telomere capping protein 5;
GN   Name=RTC5; ORFNames=CTRG_04081;
OS   Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=294747;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-3404 / T1;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: May be involved in a process influencing telomere capping.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RTC5 family. {ECO:0000305}.
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DR   EMBL; GG692399; EER32410.1; -; Genomic_DNA.
DR   RefSeq; XP_002549784.1; XM_002549738.1.
DR   AlphaFoldDB; C5MCY0; -.
DR   SMR; C5MCY0; -.
DR   STRING; 294747.C5MCY0; -.
DR   PRIDE; C5MCY0; -.
DR   EnsemblFungi; EER32410; EER32410; CTRG_04081.
DR   GeneID; 8297059; -.
DR   KEGG; ctp:CTRG_04081; -.
DR   VEuPathDB; FungiDB:CTRG_04081; -.
DR   eggNOG; ENOG502QV3R; Eukaryota.
DR   HOGENOM; CLU_011918_1_0_1; -.
DR   OrthoDB; 714794at2759; -.
DR   Proteomes; UP000002037; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006571; TLDc_dom.
DR   Pfam; PF07534; TLD; 1.
DR   SMART; SM00584; TLDc; 1.
DR   PROSITE; PS51886; TLDC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..625
FT                   /note="Restriction of telomere capping protein 5"
FT                   /id="PRO_0000408820"
FT   DOMAIN          335..571
FT                   /note="TLDc"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01234"
FT   REGION          305..327
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        312..327
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   625 AA;  72023 MW;  0E6F185647494631 CRC64;
     MGQATSNIDP QEKRDIVQEF TKEELQTLFY HRCLSLLKPI EVAFLKQDLN GKTSVTADDL
     GKLFKFPENT NSFSEGTLNI LYHVMKLIGK FPFINNNNLA IEETLSFEEL VVSLVFFSGR
     YKKIFNSDYD FLKLLFISLS DRPQTKDSKT IDEKNVDPGT EKFKTNLIVA LEEEDKQELR
     ARKINWSKLD VIKDFDHTEV QQLSVNAKRL QDMTTLCLIL NAIVRHNHDA IQKQLVEYSD
     RWREFEVYSL YLLRYLDVYL ELDKLENQKI SYDSFSKGIN GLLPYFFQIN LNRMVCDSLL
     SSNSPMATKP TEEHNDSTES TPQKKHTFPK FQETKVVSIP FLSYVSSMLQ GIGNPTILSP
     SNLVKLYAGS EAGFSIRSLE TKIFKWQAPT LVVVSGKRLK SKTMQTNRRY QKFDEMYPRH
     FLASENHLRD WQHESDRITY AVLVNQPWKS SNKNNFGDEK SIILSISPRA DYFKSVHSSI
     LQGQSIYFNN LGMGLGFGNN QPLNKNDTKR FIPGDMSLTI EANLEFAVFR HLVNSSSSND
     KFFHNSQQSH ISHEDYEDRF TISTIEVWGL LVSGKELEEQ KKQWEWEEKQ AEARQNVNIR
     NLGEERAFLE MAGLVGNHGA AGGSM