ID   RTC5_CLAL4              Reviewed;         646 AA.
AC   C4Y146;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 37.
DE   RecName: Full=Restriction of telomere capping protein 5;
GN   Name=RTC5; ORFNames=CLUG_01928;
OS   Clavispora lusitaniae (strain ATCC 42720) (Yeast) (Candida lusitaniae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Metschnikowiaceae; Clavispora.
OX   NCBI_TaxID=306902;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 42720;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: May be involved in a process influencing telomere capping.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RTC5 family. {ECO:0000305}.
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DR   EMBL; CH408077; EEQ37805.1; -; Genomic_DNA.
DR   RefSeq; XP_002618469.1; XM_002618423.1.
DR   AlphaFoldDB; C4Y146; -.
DR   SMR; C4Y146; -.
DR   STRING; 306902.C4Y146; -.
DR   EnsemblFungi; EEQ37805; EEQ37805; CLUG_01928.
DR   GeneID; 8498622; -.
DR   KEGG; clu:CLUG_01928; -.
DR   VEuPathDB; FungiDB:CLUG_01928; -.
DR   HOGENOM; CLU_011918_1_0_1; -.
DR   InParanoid; C4Y146; -.
DR   OMA; SHHVLTW; -.
DR   Proteomes; UP000007703; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006571; TLDc_dom.
DR   Pfam; PF07534; TLD; 1.
DR   SMART; SM00584; TLDc; 1.
DR   PROSITE; PS51886; TLDC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..646
FT                   /note="Restriction of telomere capping protein 5"
FT                   /id="PRO_0000408821"
FT   DOMAIN          358..594
FT                   /note="TLDc"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01234"
SQ   SEQUENCE   646 AA;  73072 MW;  D0C1CBF13DC8919F CRC64;
     MGQNASATKT QATYKQTLPK SRIKELFQTR ALQTLSAREL ASIASKLNIA SFNDSHVVTL
     TDLAYLLQLS NDKEKNVSSI HEDFACVVRI LYDSLTILGN LPFLGDSLEA DDNSQLTLKS
     LIVASAVHTG RINSFWNDAE YLKLLFISLS FPPTKQSSEK AAEKWEQVNE DSAELSFRTV
     PDEKDSSAQI ALKIKWADFE HLTTYDDLDV ECLRVPADNM VKLITLLLLV RSVRLQSHDK
     MQFLLQERIE KCWNKFEGAA LSLVRFMNVD VNASNMNSKC ITYEQFNSGV VNGFLNLFTD
     VFRRLFENGF LGSIVADPKA PQPLNENIEA TATEKESKAA ADKKQERIKK AYNFEETRLV
     NDASLALIAT ALQASGINEE ISRETVVELY NGAHAGFSIR SLESKIFKWQ APTIFLISGK
     RLRSKTIAQN KRYQQFEDMF PRFFRSTENP RKAWQTDSDK ITYAVYVEEP WRNSNKSNFG
     NELTTIVNLS PRYDIYTSKH DPVIKGMSVY FNNLGMGIGF GNDQPINKNN VRRIIPGKVS
     LTVEANLEFA VFRHIFNSSA NTSAFFNFSR QEAARNEDYE DRFMITDLEV WGIGSTKELE
     EQKKQWEWEE KQAQARQSVN VGTLSEDRAL LEMAGLIGNH GSGGSV