ID   RTC5_COCP7              Reviewed;         666 AA.
AC   C5P441;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-SEP-2009, sequence version 1.
DT   25-MAY-2022, entry version 38.
DE   RecName: Full=Restriction of telomere capping protein 5;
GN   Name=RTC5; ORFNames=CPC735_063320;
OS   Coccidioides posadasii (strain C735) (Valley fever fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX   NCBI_TaxID=222929;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C735;
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA   Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA   McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA   Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA   Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT   and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
CC   -!- FUNCTION: May be involved in a process influencing telomere capping.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RTC5 family. {ECO:0000305}.
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DR   EMBL; ACFW01000015; EER28459.1; -; Genomic_DNA.
DR   RefSeq; XP_003070604.1; XM_003070558.1.
DR   AlphaFoldDB; C5P441; -.
DR   SMR; C5P441; -.
DR   EnsemblFungi; EER28459; EER28459; CPC735_063320.
DR   GeneID; 9696099; -.
DR   KEGG; cpw:CPC735_063320; -.
DR   VEuPathDB; FungiDB:CPC735_063320; -.
DR   HOGENOM; CLU_011918_1_0_1; -.
DR   Proteomes; UP000009084; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006571; TLDc_dom.
DR   Pfam; PF07534; TLD; 1.
DR   SMART; SM00584; TLDc; 1.
DR   PROSITE; PS51886; TLDC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm.
FT   CHAIN           1..666
FT                   /note="Restriction of telomere capping protein 5"
FT                   /id="PRO_0000408822"
FT   DOMAIN          364..592
FT                   /note="TLDc"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01234"
FT   REGION          329..354
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        329..344
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   666 AA;  72540 MW;  1EEB39B8567B0310 CRC64;
     MGAGQSTRSS LNKSSPEELS HVLAHRFASK CFTPLELTHF KDNFNSRALD ENGLRHWNEE
     ILSQFLGIPD GAGEKAGPHT DATLDAGPVI FRMVSYLGAF PFQNTLAPSV LTYEAIIKVV
     VLLTERYGRV LRRGRKDRIK LLFGSLADVG RTQVEEKEMP VQESNDGKAN GIAKGNPSHV
     TGFAIDAPAN DDEEEEDDDD DLALAALESL DAIEVFKHDQ RIDRSVYKAR VSIDTFRRLI
     ALILVIAPLH PIGTTSKLIA DQDAESIDAI QAQVDSIIAA FGEEADNDGI TYKSFSRVLR
     TSLPFLFDPL TPLFEHFLFS KNLDLSRRKE SRSTEPEHEK SSSTPPPHSP HSESVFLPGP
     FESNILNTAL LSHLSFFLST SYPLPNLFRN GTRLHPVFSS VYHGESLTAF SHHVLTWHAP
     SILLLKGVTD SSSSRQDTVL VGAYLPEPWK QSSTTSSDHA SDYLDSSKFP CLFQLLPTHT
     VLLASPFFKT LKFNMPVASF STKSGIALGC MIPPSSRTSL HHDLRPRPAG GGSLIIDPAL
     ENATFVVSDG LNGDGVFLPP GLSPSSSSSF SASALSSTTS ISVHAIEVWG VVPTQPELGP
     VLDPDSSRGD AVAAQKAAWD FEAREAERRR TIHLKVGGGD SEEQTGRALL EMAGIIGDSN
     YSPRKH