RTC5_EMENI
ID RTC5_EMENI Reviewed; 653 AA.
AC Q5B6J2; C8V6J5;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 26-APR-2005, sequence version 1.
DT 25-MAY-2022, entry version 65.
DE RecName: Full=Restriction of telomere capping protein 5;
GN Name=rtc5; ORFNames=AN3838;
OS Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS M139) (Aspergillus nidulans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Nidulantes.
OX NCBI_TaxID=227321;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=16372000; DOI=10.1038/nature04341;
RA Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S.,
RA Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S.,
RA Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT fumigatus and A. oryzae.";
RL Nature 438:1105-1115(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA Oliver S.G., Turner G.;
RT "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT effort.";
RL Fungal Genet. Biol. 46:S2-13(2009).
CC -!- FUNCTION: May be involved in a process influencing telomere capping.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RTC5 family. {ECO:0000305}.
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DR EMBL; AACD01000062; EAA59103.1; -; Genomic_DNA.
DR EMBL; BN001302; CBF75269.1; -; Genomic_DNA.
DR RefSeq; XP_661442.1; XM_656350.1.
DR AlphaFoldDB; Q5B6J2; -.
DR SMR; Q5B6J2; -.
DR STRING; 227321.Q5B6J2; -.
DR EnsemblFungi; CBF75269; CBF75269; ANIA_03838.
DR EnsemblFungi; EAA59103; EAA59103; AN3838.2.
DR GeneID; 2873258; -.
DR KEGG; ani:AN3838.2; -.
DR eggNOG; ENOG502QV3R; Eukaryota.
DR HOGENOM; CLU_011918_1_0_1; -.
DR InParanoid; Q5B6J2; -.
DR OMA; SHHVLTW; -.
DR OrthoDB; 714794at2759; -.
DR Proteomes; UP000000560; Chromosome II.
DR Proteomes; UP000005890; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0006979; P:response to oxidative stress; IBA:GO_Central.
DR InterPro; IPR006571; TLDc_dom.
DR Pfam; PF07534; TLD; 1.
DR PROSITE; PS51886; TLDC; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Reference proteome.
FT CHAIN 1..653
FT /note="Restriction of telomere capping protein 5"
FT /id="PRO_0000408825"
FT DOMAIN 361..572
FT /note="TLDc"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01234"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 165..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..28
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..181
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 653 AA; 71600 MW; E379F2CFE6CBDE2C CRC64;
MGVGQSHEDA GYTSPDLTPN LFPSSKNKSD ADAEQLSLKL AERFATKCFT PLELTHFKDN
FYQRATEQGG LKYWNEKTLS DFLSIPDHSD SHCPLDAGPV IFRMASYLGA FPFQNSLAPS
VLTLEALIKV VVLLTERYGK VLRRGQKNRI RLLFGSLADV ARKEIEKPAE NEGKEEDIPA
PSQTRGFDID APANDNYDED DEDDLALAAL ESLDAIEVFK HDSRIDKRVY EARISLSTFR
RLLMLLLVIA PLKPLEDISN YTVDLNETRM LSVREEADSI LAAFEQEASG GISYKTFADT
ITSSFPYLFD PLTPLFEHLL FSKNLDFSQH RGSDTTEAEQ MSQPVKSSLA SITLPGSFES
TILSPSIISH LSFFLPSTSD NQNLLHGNVR LHPVFSIAAH GSSLTSFSHN VLTWQSGTLF
LLYGQDTDTG DMLTLGAYLP QPWKSPTTSQ STSDFSSSVL PCLFLLSPYH ILLRGNPSPS
VVDKPNTPTA YFSTHHGIAI GCRIPPSSRT QKLPPTPLGA GSLVIGTSLE SAELHISPFG
HDGVFLPPGA QPTKSKSETN IDIYNLEVWG LVPGSNPNGS SSLQKSAVEL QQASWDFEAR
EAERRRHVNL SAGAGDSALE QARWLLETAG VIGDSSGTGR CSRQYGVVTM CYQ
