ID   RTC5_KOMPG              Reviewed;         577 AA.
AC   C4R3K5;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   07-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 47.
DE   RecName: Full=Restriction of telomere capping protein 5;
GN   Name=RTC5; OrderedLocusNames=PAS_chr3_0111;
OS   Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Phaffomycetaceae; Komagataella.
OX   NCBI_TaxID=644223;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GS115 / ATCC 20864;
RX   PubMed=19465926; DOI=10.1038/nbt.1544;
RA   De Schutter K., Lin Y.-C., Tiels P., Van Hecke A., Glinka S.,
RA   Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT   "Genome sequence of the recombinant protein production host Pichia
RT   pastoris.";
RL   Nat. Biotechnol. 27:561-566(2009).
CC   -!- FUNCTION: May be involved in a process influencing telomere capping.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RTC5 family. {ECO:0000305}.
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DR   EMBL; FN392321; CAY70040.1; -; Genomic_DNA.
DR   RefSeq; XP_002492320.1; XM_002492275.1.
DR   AlphaFoldDB; C4R3K5; -.
DR   SMR; C4R3K5; -.
DR   STRING; 644223.C4R3K5; -.
DR   EnsemblFungi; CAY70040; CAY70040; PAS_chr3_0111.
DR   GeneID; 8199391; -.
DR   KEGG; ppa:PAS_chr3_0111; -.
DR   eggNOG; ENOG502QV3R; Eukaryota.
DR   HOGENOM; CLU_011918_1_0_1; -.
DR   InParanoid; C4R3K5; -.
DR   OMA; SHHVLTW; -.
DR   Proteomes; UP000000314; Chromosome 3.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006571; TLDc_dom.
DR   Pfam; PF07534; TLD; 1.
DR   SMART; SM00584; TLDc; 1.
DR   PROSITE; PS51886; TLDC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..577
FT                   /note="Restriction of telomere capping protein 5"
FT                   /id="PRO_0000408840"
FT   DOMAIN          301..524
FT                   /note="TLDc"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01234"
SQ   SEQUENCE   577 AA;  65251 MW;  53E51A0846773666 CRC64;
     MGQSVSSEEE TKQDYRTVKV SKGQLQRLFD KNCLSLLTPI EVYSLKENLH VRDINNDKQL
     SIDETVQLLG LPKDCPCNEV VYDFVRVLGW FPFFNSVDPL KGISLPMLIR SVVLSRSKSF
     FKLFKGDSSY KFEDLVFLVL SILSEPKDLV EKNLDSSCDE TGVLELALQG DSNIHWAQCK
     VIKDFDNTNI KERKVSAYNL AIFLTFLLAI SRPLMSDYSQ HLSQWSNFMS HGMNLVRSFD
     SSITERSLHS KTVGYAAFIS TIETKMPNVL HPLDALLDSL LFMKQSKGAS DVTPEFSVST
     KLINEYSLAQ LSTVLPLELC YSRLRKLYVG SESGFSMRSF ESKCFNWNAP TITFISGHRI
     TSKKTKRYLL FEEQFPRSRA AEDETGSDFD HANDDSARLT FAVFLNQHWK TSNKEPFGDS
     KTTIFQLSPR QAVFKSSTFR KDYCYFNTSG GGIGFGNEEP YLKNNTTKFR PGNVSLTIDS
     GLEFCVFRHL GKGGSFNPMV LEDDSIPVYE DRFVISDLEV WGCGSEKELL EQAKRWAWEE
     KEAMARQRIN ADTLGEERAF LEMAGLVGNH GASGGSV