ID   RTC5_LACTC              Reviewed;         554 AA.
AC   C5DJG1;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 46.
DE   RecName: Full=Restriction of telomere capping protein 5;
GN   Name=RTC5; OrderedLocusNames=KLTH0F16126g;
OS   Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS   (Yeast) (Kluyveromyces thermotolerans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=559295;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284;
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- FUNCTION: May be involved in a process influencing telomere capping.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RTC5 family. {ECO:0000305}.
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DR   EMBL; CU928170; CAR24450.1; -; Genomic_DNA.
DR   RefSeq; XP_002554887.1; XM_002554841.1.
DR   AlphaFoldDB; C5DJG1; -.
DR   SMR; C5DJG1; -.
DR   STRING; 559295.C5DJG1; -.
DR   EnsemblFungi; CAR24450; CAR24450; KLTH0F16126g.
DR   GeneID; 8293118; -.
DR   KEGG; lth:KLTH0F16126g; -.
DR   eggNOG; ENOG502QV3R; Eukaryota.
DR   HOGENOM; CLU_011918_1_0_1; -.
DR   InParanoid; C5DJG1; -.
DR   OMA; SHHVLTW; -.
DR   OrthoDB; 714794at2759; -.
DR   Proteomes; UP000002036; Chromosome F.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006571; TLDc_dom.
DR   Pfam; PF07534; TLD; 1.
DR   SMART; SM00584; TLDc; 1.
DR   PROSITE; PS51886; TLDC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..554
FT                   /note="Restriction of telomere capping protein 5"
FT                   /id="PRO_0000408827"
FT   DOMAIN          284..502
FT                   /note="TLDc"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01234"
SQ   SEQUENCE   554 AA;  62089 MW;  49E3EF5B8EA32DCC CRC64;
     MGQNSSNTVS SSQSSTHFES ENDLLSWYDK KALKLVSTPE LVSYKGNIDG KPLDAALNRK
     ELMRVLRLQN ANEAVEGLLF NCVQTLANFP LIKDCYENVT YMGVLKSCVL LNKNRCLEYV
     QDKRYNHTKL VYISLALNKA VKEMSSLPNS NDSLDAPKVI ATFNNVAEEE LVVPAETMLE
     FLTLMLTMSK ATVIKNSRLD VNISEKWDSF KTCALSILRT MNTDILTSQD ALKNVISYTQ
     FQNVISSVCP NLLVPLECLM EHVLFLNRDL VDLEASKPLI PQSKLVTEPL LAQLATVWPR
     ELVFSRLQKL YVGRDSGFSM RSFQAKAFKW MAPSILLVQG SRIPDDQDYA KNKNQRYKKF
     LDEYPRLKDE DQHILPALSG KRKLLFAILI NEPWKVTNSE LFGDIKTTIV QLSPIQEVYK
     ASKPGNVYFN TLGGGIGIGS PQPIIKSSGV KFVPGNVSLT IDPNLEFAAF RNVGFGGSIA
     PSNTPTSEHK FLIQDIETWG CGGEKELEEQ MKNWEWEEAE AQRRQRINLK SVNDDRALLE
     LAGLVGQNQS GGSV