ID   RTC5_LODEL              Reviewed;         635 AA.
AC   A5DSQ8;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   03-AUG-2022, entry version 49.
DE   RecName: Full=Restriction of telomere capping protein 5;
GN   Name=RTC5; ORFNames=LELG_00394;
OS   Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC
OS   1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade;
OC   Lodderomyces.
OX   NCBI_TaxID=379508;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11503 / BCRC 21390 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL
RC   YB-4239;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: May be involved in a process influencing telomere capping.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RTC5 family. {ECO:0000305}.
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DR   EMBL; CH981524; EDK42216.1; -; Genomic_DNA.
DR   RefSeq; XP_001527874.1; XM_001527824.1.
DR   AlphaFoldDB; A5DSQ8; -.
DR   STRING; 379508.A5DSQ8; -.
DR   EnsemblFungi; EDK42216; EDK42216; LELG_00394.
DR   GeneID; 5235227; -.
DR   KEGG; lel:LELG_00394; -.
DR   VEuPathDB; FungiDB:LELG_00394; -.
DR   eggNOG; ENOG502QV3R; Eukaryota.
DR   HOGENOM; CLU_011918_1_0_1; -.
DR   InParanoid; A5DSQ8; -.
DR   OrthoDB; 714794at2759; -.
DR   Proteomes; UP000001996; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006571; TLDc_dom.
DR   Pfam; PF07534; TLD; 1.
DR   SMART; SM00584; TLDc; 1.
DR   PROSITE; PS51886; TLDC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..635
FT                   /note="Restriction of telomere capping protein 5"
FT                   /id="PRO_0000408829"
FT   DOMAIN          346..583
FT                   /note="TLDc"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01234"
FT   REGION          297..333
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        297..318
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   635 AA;  72337 MW;  039456FCFE153274 CRC64;
     MSCFKQDVYN CITPKTLSFV KSFLKQRSND PAASTHLSSA RVVEWNLNGI EVDSRARDEL
     KAAVNILFRI MKYIGQFPFP KLSSKDDSEI ISLTVQEFVI ASVFISGRYR KLFGNDNGEI
     IWKFLFIALS HQSDMNFFED DLDHLFTIPL KYPIEDGDSI AIKAQKVDWG GLEIIKKLSN
     LDMNQLQLQP SLFLNLTTLF LLTESIPNQK HNKMHDQFVH NLTTWKDFRK YSLDLLRYMN
     NDLSKDDLNS QTLSWSEFSL GMNNLLAPFV EVNLRKVVEN NVLNISLPFF ETSANSKMDG
     TGDEVPNGAT TGTKTTMKEN EGAGVEAQSK EETKVGNDVE SSFGSKLVSI SLIAYISSML
     RGIGSTIEVT RFNAIKLFAG LEAGFSIRSL ENKIYKWHAP TLLFVSGKRI KQRTIDTNRR
     YQEFDETYPK FFQANEDLLK SWQYTNDRIT YCVLINQPWQ NSNKKNFGDE KSLILSLEPR
     ADYYTSLHSE ILKGQLIYFN NSGMGLGFGN AQPLNKSNNK KYYPGDVSLT IESNLEFAVF
     RHLGSLSTNA TTYFNRSRLP STVAHEDFED RFLITDLEVW GIGSKKELEE QQRQWKWEEQ
     QAEARQSVNI RNMGEERAFL EMAGLVGNNG SGGSL