ID   RTC5_NEOFI              Reviewed;         641 AA.
AC   A1CXG7;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 1.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=Restriction of telomere capping protein 5;
GN   Name=rtc5; ORFNames=NFIA_108120;
OS   Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164
OS   / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=331117;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181
RC   / WB 181;
RX   PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA   Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA   Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA   Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA   Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA   Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA   White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA   Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT   "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT   fumigatus.";
RL   PLoS Genet. 4:E1000046-E1000046(2008).
CC   -!- FUNCTION: May be involved in a process influencing telomere capping.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RTC5 family. {ECO:0000305}.
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DR   EMBL; DS027685; EAW25319.1; -; Genomic_DNA.
DR   RefSeq; XP_001267216.1; XM_001267215.1.
DR   AlphaFoldDB; A1CXG7; -.
DR   STRING; 331117.A1CXG7; -.
DR   EnsemblFungi; EAW25319; EAW25319; NFIA_108120.
DR   GeneID; 4593317; -.
DR   KEGG; nfi:NFIA_108120; -.
DR   VEuPathDB; FungiDB:NFIA_108120; -.
DR   eggNOG; ENOG502QV3R; Eukaryota.
DR   HOGENOM; CLU_011918_1_0_1; -.
DR   OMA; SHHVLTW; -.
DR   OrthoDB; 714794at2759; -.
DR   Proteomes; UP000006702; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006571; TLDc_dom.
DR   Pfam; PF07534; TLD; 1.
DR   SMART; SM00584; TLDc; 1.
DR   PROSITE; PS51886; TLDC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..641
FT                   /note="Restriction of telomere capping protein 5"
FT                   /id="PRO_0000408832"
FT   DOMAIN          354..570
FT                   /note="TLDc"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01234"
FT   REGION          149..168
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        149..166
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   641 AA;  69314 MW;  03F804905B617595 CRC64;
     MGVGQSTELP GHAGTPEHLS HVLAERFATK CFTPLELTHF KDNFFSRAID QGGMKYWNEK
     ILSDFLGIPD SSDSHCPLDA GPVIFRMVSY LGAFPFQNTL APSVLTFEAM VKVAVLLTER
     YGKVLRPARK DRIKLLFGSL ADVGRRDVGA SPGAEDVRKE TDDSSAVKSH VTGFEVDAPA
     NDDYGDEDED DDDLALAALE SLDAIDVFKH DSRIDKKVYE ARISVATFRR LLMLLIVIAP
     LKTLEPVTSY SSDLNEARME SVRKEADTIL AAFSTEDSDG GISYRSFANI TSTALPYLFD
     PLTPLFEHLL FSKNLDMTKK SGSDAIVTDT IEKPSDSPGP SPSTIMLPGS FESSILKPSV
     VSHLSFFLPS PTSNVNLLRG NMRLHPVFST AVHGSSLTSF SHNVLTWNAG TLLLLEGAVS
     EPSEHGEGMV TLGAYLPQPW KSAPLSHSST KPSDSSALPC LFELSPKHQL LQGNPSPSVQ
     KPNAPVAYFS TSTGIAIGCQ VPPPSRSQLL TPTPLGAGSL TIDTSLDSAT FYMSSIGHNG
     VFLPPATTSM SEETVKKQID IYTLEIWGLV PEPSDASSAE PRQSAVELQR AKWEFEAREA
     ERRRNLNLKA GAGDSAMEGA RWLLETAGLI GDRPGQRGGS I