ID   RTC5_PARBA              Reviewed;         689 AA.
AC   C1GYL0;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   26-MAY-2009, sequence version 1.
DT   25-MAY-2022, entry version 48.
DE   RecName: Full=Restriction of telomere capping protein 5;
GN   Name=RTC5; ORFNames=PAAG_03164;
OS   Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides
OS   brasiliensis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX   NCBI_TaxID=502779;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-826 / Pb01;
RX   PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA   Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA   Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA   Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA   Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA   Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA   Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA   Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA   Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT   "Comparative genomic analysis of human fungal pathogens causing
RT   paracoccidioidomycosis.";
RL   PLoS Genet. 7:E1002345-E1002345(2011).
CC   -!- FUNCTION: May be involved in a process influencing telomere capping.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RTC5 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EEH41601.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; KN293999; EEH41601.2; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_015702076.1; XM_015844870.1.
DR   AlphaFoldDB; C1GYL0; -.
DR   STRING; 502779.C1GYL0; -.
DR   EnsemblFungi; EEH41601; EEH41601; PAAG_03164.
DR   GeneID; 9097973; -.
DR   KEGG; pbl:PAAG_03164; -.
DR   eggNOG; ENOG502QV3R; Eukaryota.
DR   HOGENOM; CLU_011918_1_0_1; -.
DR   OrthoDB; 714794at2759; -.
DR   Proteomes; UP000002059; Partially assembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006571; TLDc_dom.
DR   Pfam; PF07534; TLD; 1.
DR   SMART; SM00584; TLDc; 1.
DR   PROSITE; PS51886; TLDC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..689
FT                   /note="Restriction of telomere capping protein 5"
FT                   /id="PRO_0000408834"
FT   DOMAIN          370..611
FT                   /note="TLDc"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01234"
FT   REGION          166..201
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          332..359
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        342..359
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   689 AA;  74644 MW;  DC73027E723FF7E1 CRC64;
     MGASQSTNGP GQKTTSVEEL SKRLAYRFAN KCFTPLELTH LKDNFFSRAL DQGGIRYWNE
     EILSEFLGIP DGAGSAAYVT SDGSLDAGPV IFRMVSYLGA FPFQNTMAPS VLTFEAMVKV
     IVLLTERYGK VLRRGRKDRV KLLYGSLADV GRRDIIVQLQ EAAEDSMESV GEAGPGSDRT
     FTHSTGFSVD KPAHDDDGEE DDDDLALAAL ESLDAIEIFK HDQRIDKTVY ESKISINTFR
     RLLALLMVTA PLRPLGTISK YTTGLSSSIL ETVHEQVESI LAALALDDLE GGIGYKSFSE
     LISTSLPYLF DPLTPLFEHL LFSKNLDLTR KRHSQSQNDP AAKPVPTPPS TPPSSPPLSP
     VILNGGFDSS ILNPALLSHL SFFLSTSAQI PNIFRNRTRL HPVFSSTEHG ESLTSFSHHV
     MTWQAPSILL IKGAVTSESD EEQITTIGAY LPQPWKQSSS YSSRRSSDVP DQSTLPCLFE
     LSPVHTVLQG SPSLSSLKPN MPVTYFSTKT GIAIGCQIPP PSRKSLGADF LPKPSGGGSL
     LIDPALEVAT LVISDGLNGE GVFLPPGISA HSASKSVSCT TLAASTTSIS ASNHNTTKSI
     SIYSLEVWGI IPSQSLSAQL DSPGSFVDKQ DAITQQRAQW DFEAREAERR KVINMKVGVG
     ELEEHSGRAL LEMAGIVGDS QYSGLRHLR