ID   RTC5_PARBD              Reviewed;         689 AA.
AC   C1G788;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   26-MAY-2009, sequence version 1.
DT   25-MAY-2022, entry version 40.
DE   RecName: Full=Restriction of telomere capping protein 5;
GN   Name=RTC5; ORFNames=PADG_03043;
OS   Paracoccidioides brasiliensis (strain Pb18).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX   NCBI_TaxID=502780;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pb18;
RX   PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA   Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA   Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA   Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA   Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA   Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA   Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA   Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA   Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT   "Comparative genomic analysis of human fungal pathogens causing
RT   paracoccidioidomycosis.";
RL   PLoS Genet. 7:E1002345-E1002345(2011).
CC   -!- FUNCTION: May be involved in a process influencing telomere capping.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RTC5 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EEH46945.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; KN275959; EEH46945.2; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_010758245.1; XM_010759943.1.
DR   AlphaFoldDB; C1G788; -.
DR   STRING; 502780.C1G788; -.
DR   PRIDE; C1G788; -.
DR   EnsemblFungi; EEH46945; EEH46945; PADG_03043.
DR   GeneID; 22582415; -.
DR   KEGG; pbn:PADG_03043; -.
DR   eggNOG; ENOG502QV3R; Eukaryota.
DR   HOGENOM; CLU_011918_1_0_1; -.
DR   Proteomes; UP000001628; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006571; TLDc_dom.
DR   Pfam; PF07534; TLD; 1.
DR   SMART; SM00584; TLDc; 1.
DR   PROSITE; PS51886; TLDC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..689
FT                   /note="Restriction of telomere capping protein 5"
FT                   /id="PRO_0000408835"
FT   DOMAIN          370..611
FT                   /note="TLDc"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01234"
FT   REGION          173..201
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          332..359
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        342..359
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   689 AA;  74673 MW;  41CE51605D6EE99B CRC64;
     MGASQSTNGP GQKTTSVEEL SKRLAYRFAN KCFTPLELTH LKDNFFSRAL DQGGIRYWNE
     EILSEFLGIP DGAGSAAYVT SDGSLDAGPV IFRMVSYLGA FPFHNTMAPS VLTFEAMVKV
     IVLLTERYGK VLKRGRKDRV KLLFGSLADV GRRDIVVQLQ EAAEDSLELI GEAGPGSDRT
     FTHPTGFSVD KPAHDDDGEE DDDDLALAAL ESLDAIEIFK HDQRIDKTVY ESKISINTFR
     RLLAFLMVTA PLRPLGTISK YTTGLSSSIL ETVNEQVESI LAALALDDLE GGIGYKSFSE
     LISTSLPYLF DPLTPLFEHL LFSKNLDVTR KRHSQSQNDP AAKPVPTPPS TPPSSPPLSP
     VILNGGFDSS ILNPTLLSHL SFFLSTTAQI PNIFRNRTRL HPVFSSTEHG ESLTSFSHHV
     MTWQAPSILL IKGVVTSESD EEQITTIGAY LPQPWKQSSS NSSRRSSDVP DQSTLPCLFE
     LSPVHTVLQG SPSLSSLKPN MPITYFSTKT GIAIGCQIPP PSRKSLGADF LPKPSGGGSL
     LIDPALEVAT LVISDGLNGE GVFLPPGISA HSASKSVSCT TLAASTASIS ASNHNTTKSI
     SIYSLEVWGI IPSQSLSVQL DSPGSFVEKQ DAITQQRAQW DFEAREAERR KVINMKVGVG
     ELEEHSGRAL LEMAGIVGDS QYSGLRHLR