ID   RTC5_PARBP              Reviewed;         689 AA.
AC   C0RYV6;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 1.
DT   25-MAY-2022, entry version 30.
DE   RecName: Full=Restriction of telomere capping protein 5;
GN   Name=RTC5; ORFNames=PABG_00611;
OS   Paracoccidioides brasiliensis (strain Pb03).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX   NCBI_TaxID=482561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pb03;
RX   PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA   Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA   Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA   Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA   Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA   Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA   Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA   Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA   Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT   "Comparative genomic analysis of human fungal pathogens causing
RT   paracoccidioidomycosis.";
RL   PLoS Genet. 7:E1002345-E1002345(2011).
CC   -!- FUNCTION: May be involved in a process influencing telomere capping.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RTC5 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EEH18048.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KN305531; EEH18048.2; ALT_SEQ; Genomic_DNA.
DR   AlphaFoldDB; C0RYV6; -.
DR   EnsemblFungi; EEH18048; EEH18048; PABG_00611.
DR   HOGENOM; CLU_011918_1_0_1; -.
DR   InParanoid; C0RYV6; -.
DR   Proteomes; UP000002740; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006571; TLDc_dom.
DR   Pfam; PF07534; TLD; 1.
DR   SMART; SM00584; TLDc; 1.
DR   PROSITE; PS51886; TLDC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm.
FT   CHAIN           1..689
FT                   /note="Restriction of telomere capping protein 5"
FT                   /id="PRO_0000408836"
FT   DOMAIN          370..611
FT                   /note="TLDc"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01234"
FT   REGION          173..201
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          332..359
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        342..359
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   689 AA;  74588 MW;  086FBA328B953A54 CRC64;
     MGASQSTNGP GQKTTSVEEL SKRLAYRFAN KCFTPLELTH LKDNFFSRAL DQGGIRYWNE
     EILSEFLGIP DGAGSAAYVT SDGSLDAGPV IFRMVSYLGA FPFQNTMAPS VLTFEAMVKV
     IVLLTERYGK VLKRGRKDRV KLLFGSLADV GRRDIVVQLQ EAAEDSLELI GEAGPGSDRT
     FTHPTGFSVD KPAHDDDGEE DDDDLALAAL ESLDAIEIFK HDQRIDKTVY ESKISINTFR
     RLLALLMVTA PLRPLGTISK YTTGLSSSIL ETVNEQVESI LAALALDDLE GGIGYKSFSE
     LISTSLPYLF DPLTPLFEHL LFSKNLDVTR KRHSQSQNDP AAKPVPTPPS TPPSSPPLSP
     VILNGGFDSS ILNPTLLSHL SFFLSTTAQI PNIFRNRTRL HPVFSSTEHG ESLTSFSHHV
     MTWQAPSILL IKGVVTSESD EEQITTIGAY LPQPWKQSSS NSSRRSSDVP DQSTLPCLFE
     LSPVHTVLQG SPSLSSLKPN MPVTYFSTKT GIAIGCQIPP PSRKSLGADF LPKPSGGGSL
     LIDPALEVAT LVISDGLNGE GVFLPPGISA HSASKSVSCT TLAASTASIS ASNHNTTKSI
     SIYSLEVWGI IPSQSLSAQL DSPGSFVEKQ DAITQQRAQW DFEAREAERR KVINMKVGVG
     ELEEHSGRAL LEMAGIVGDS QYSGLRHLR