ID   RTC5_PICGU              Reviewed;         575 AA.
AC   A5DMB8;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   22-JUL-2008, sequence version 2.
DT   03-AUG-2022, entry version 47.
DE   RecName: Full=Restriction of telomere capping protein 5;
GN   Name=RTC5; ORFNames=PGUG_04419;
OS   Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS   / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX   NCBI_TaxID=294746;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: May be involved in a process influencing telomere capping.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RTC5 family. {ECO:0000305}.
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DR   EMBL; CH408159; EDK40321.2; -; Genomic_DNA.
DR   RefSeq; XP_001483690.1; XM_001483640.1.
DR   AlphaFoldDB; A5DMB8; -.
DR   SMR; A5DMB8; -.
DR   STRING; 294746.A5DMB8; -.
DR   EnsemblFungi; EDK40321; EDK40321; PGUG_04419.
DR   GeneID; 5125468; -.
DR   KEGG; pgu:PGUG_04419; -.
DR   VEuPathDB; FungiDB:PGUG_04419; -.
DR   eggNOG; ENOG502QV3R; Eukaryota.
DR   HOGENOM; CLU_011918_1_0_1; -.
DR   InParanoid; A5DMB8; -.
DR   OrthoDB; 714794at2759; -.
DR   Proteomes; UP000001997; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006571; TLDc_dom.
DR   Pfam; PF07534; TLD; 1.
DR   SMART; SM00584; TLDc; 1.
DR   PROSITE; PS51886; TLDC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..575
FT                   /note="Restriction of telomere capping protein 5"
FT                   /id="PRO_0000408839"
FT   DOMAIN          293..523
FT                   /note="TLDc"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01234"
SQ   SEQUENCE   575 AA;  64103 MW;  B0538C82B9D62674 CRC64;
     MGQSSSAESF SHSYSPQQVH TLLSYACQRL ITPVEAQTLR KKLNSTTVNE KAQLSRADLA
     QLLLLNDPPS SVVYKCLQKL GKFPFFGEEN DSTITADELI VASMLISGRF KKLKLNTDYD
     KLIFRALATS KLDAVTEKSE QLPVSVKFGR GIENPEHLQM ASRFVDWSSM SGFESVDTDG
     YFISRSEMVQ LLALFLVIYS IPKRKRISMQ TELSQKLDND WRSFEAAGEQ LTTFIRSSEK
     ISYQDFSSAL ALLGPLVHYG FEFLVDVMLS DTTEHSDTTE TKKGPDLEVT KSHLINSSTI
     ALLAATFAGL GGKQAGISLT RQNLVKLYLG SESGFSIRSL ESKVFKWHAP TILLVSGERL
     RTTIKRYETF DSEYPRFFRS SESPLKPWQQ PNDKITYAVL VHEPWKVSNK KNFGDTNTTI
     IALEPRLDVF KGIASESIYF NTLGMGLGFG NSQPINKNTL KRYAPGSVSL TIEANLEFAV
     FRHISSQAGS GITSFATGVQ PDISGQDYED RFLITDLEVW GVGSSKELEE QKKQWDWEKK
     QAEARQSVNL RSMGEDRALL EMVGLVGNHG SGGSV