ID   RTC5_PICST              Reviewed;         647 AA.
AC   A3LQG3;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2007, sequence version 2.
DT   03-AUG-2022, entry version 57.
DE   RecName: Full=Restriction of telomere capping protein 5;
GN   Name=RTC5; Synonyms=YBV2; ORFNames=PICST_54383;
OS   Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS   Y-11545) (Yeast) (Pichia stipitis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX   NCBI_TaxID=322104;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545;
RX   PubMed=17334359; DOI=10.1038/nbt1290;
RA   Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA   Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.-S.,
RA   Passoth V., Richardson P.M.;
RT   "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT   yeast Pichia stipitis.";
RL   Nat. Biotechnol. 25:319-326(2007).
CC   -!- FUNCTION: May be involved in a process influencing telomere capping.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RTC5 family. {ECO:0000305}.
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DR   EMBL; CP000496; ABN64675.2; -; Genomic_DNA.
DR   RefSeq; XP_001382704.2; XM_001382667.1.
DR   AlphaFoldDB; A3LQG3; -.
DR   SMR; A3LQG3; -.
DR   STRING; 322104.A3LQG3; -.
DR   EnsemblFungi; ABN64675; ABN64675; PICST_54383.
DR   GeneID; 4837265; -.
DR   KEGG; pic:PICST_54383; -.
DR   eggNOG; ENOG502QV3R; Eukaryota.
DR   HOGENOM; CLU_011918_1_0_1; -.
DR   InParanoid; A3LQG3; -.
DR   OMA; SHHVLTW; -.
DR   OrthoDB; 714794at2759; -.
DR   Proteomes; UP000002258; Chromosome 2.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006571; TLDc_dom.
DR   Pfam; PF07534; TLD; 1.
DR   SMART; SM00584; TLDc; 1.
DR   PROSITE; PS51886; TLDC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..647
FT                   /note="Restriction of telomere capping protein 5"
FT                   /id="PRO_0000408841"
FT   DOMAIN          358..594
FT                   /note="TLDc"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01234"
FT   REGION          325..346
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   647 AA;  73674 MW;  072A413F8F100031 CRC64;
     MGQIASSAND GKNNAILESF SKEQIMDLLS SRCLTLLRNV EITSITNKLN VTSLREKNVV
     TPTDLALLLQ LSNDMDRDNS SVNESFNRAL KILYESTRVI GSLPFLSNYT KTDTSGGLTI
     QELLISSLVH SARYKKIFNS QYDYLKLIFC SLALPRLAVE TNSEESSVDF LSDKPKVVEQ
     VRYPIREEDS PDIRSKKVKW DTFNIINNYD DIDISSLKVN AYDLVQIITL FLIISSIPKM
     KRDLMHQKLV GYIERWKEFE VYGLYILKYI NINLNATNLQ TETITFEEFQ TTFNRCLPNF
     FQNGFSILFK EGLLSTVVAK AGSNNSSKDI PNNPEPQKQE EEATKKKKFK LPKFEESKLV
     NAASLSYISN VVSGLGSSIE ISNQNLIKLY AGTEAGFSIR SLESKIFKWQ APTLFVVSGK
     RLKNKTIDTN MRYQQFKTEY PQYFRSSESN KHDWQNDNDK ITYAILINQP WKNSNKKNFG
     DENTIILSLS PRLDFYKSIH STVLNGESIY FNTLGLGIGF GNTQPVNKNG VKKYFPGDVS
     LTIEANLEFA VFRHIVASSA NTSTYFERSH QSQVRSSDFE DRFMITDLEV WGIGSTKDLE
     EQRKQWEWEQ KQAEARQSVN LRSLGEERAF LEMVGLVGNH NSSGGSI