ID   RTC5_SCHPO              Reviewed;         511 AA.
AC   O94644;
DT   19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Restriction of telomere capping protein 5;
GN   Name=rtc5; ORFNames=SPBC21.02;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: May be involved in a process influencing telomere capping.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC       {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the RTC5 family. {ECO:0000305}.
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DR   EMBL; CU329671; CAB36882.1; -; Genomic_DNA.
DR   PIR; T39884; T39884.
DR   RefSeq; NP_596336.1; NM_001022257.2.
DR   AlphaFoldDB; O94644; -.
DR   SMR; O94644; -.
DR   STRING; 284812.O94644; -.
DR   SwissPalm; O94644; -.
DR   MaxQB; O94644; -.
DR   PaxDb; O94644; -.
DR   EnsemblFungi; SPBC21.02.1; SPBC21.02.1:pep; SPBC21.02.
DR   GeneID; 2540756; -.
DR   KEGG; spo:SPBC21.02; -.
DR   PomBase; SPBC21.02; rtc5.
DR   VEuPathDB; FungiDB:SPBC21.02; -.
DR   eggNOG; ENOG502QV3R; Eukaryota.
DR   HOGENOM; CLU_533359_0_0_1; -.
DR   InParanoid; O94644; -.
DR   OMA; TFFGIPD; -.
DR   PhylomeDB; O94644; -.
DR   PRO; PR:O94644; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   InterPro; IPR006571; TLDc_dom.
DR   Pfam; PF07534; TLD; 1.
DR   SMART; SM00584; TLDc; 1.
DR   PROSITE; PS51886; TLDC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..511
FT                   /note="Restriction of telomere capping protein 5"
FT                   /id="PRO_0000116524"
FT   DOMAIN          274..499
FT                   /note="TLDc"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01234"
SQ   SEQUENCE   511 AA;  58748 MW;  B1605A0D4CDD7364 CRC64;
     MGQKESQFKV LWQLQTHEEY MKQTSSFLRD FNALERYNLK ENFEALSSFD NGEKIWVEDA
     FTTFFGIPDV IQLSPFFYRS ACSFGRDLNI NRQRLTFSAL ARFLASYTGR HKDVWSDFES
     NLMIIASWCD SFPKFRVEVL KNSKQISRLI HSDVQNISNF FDQNFGIRRS NIYQLCLLLL
     CISKLKPGES VGCHINSFLD SMFVKEQKAA FYVLQGISPD ISSNIIKPSY LLHFLESNPY
     FLKSLGSLFE LALFPHSAHN QKVQDDVSPL NDFAILSPLI HAQICFFLPK SVWQVNGLTS
     LFRASFHGYS MYALERKMCN YHNPSILLIK AKKINANHKS SSRPISLDAT IPRKYPPHCI
     GTDKAVPQKF GADFHNENIL LGAYISTRWR QSHMGFFGDH STLLFQLQPI HQVYYASNLD
     KNYCMFDKNV GLGFGLSRHK VTNKVQYDVP GVCMYIDDGL EYGLFRHAGD GAFKPATNYE
     NFEYEERFLI QDLEVIGVDT TKPVEPIHIG L