ID   RTC5_TALMQ              Reviewed;         689 AA.
AC   B6QHL1;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 1.
DT   25-MAY-2022, entry version 46.
DE   RecName: Full=Restriction of telomere capping protein 5;
GN   Name=rtc5; ORFNames=PMAA_094620;
OS   Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333)
OS   (Penicillium marneffei).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC   Talaromyces sect. Talaromyces.
OX   NCBI_TaxID=441960;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 18224 / CBS 334.59 / QM 7333;
RX   PubMed=25676766; DOI=10.1128/genomea.01559-14;
RA   Nierman W.C., Fedorova-Abrams N.D., Andrianopoulos A.;
RT   "Genome sequence of the AIDS-associated pathogen Penicillium marneffei
RT   (ATCC18224) and its near taxonomic relative Talaromyces stipitatus
RT   (ATCC10500).";
RL   Genome Announc. 3:E0155914-E0155914(2015).
CC   -!- FUNCTION: May be involved in a process influencing telomere capping.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RTC5 family. {ECO:0000305}.
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DR   EMBL; DS995902; EEA22856.1; -; Genomic_DNA.
DR   RefSeq; XP_002149023.1; XM_002148987.1.
DR   AlphaFoldDB; B6QHL1; -.
DR   SMR; B6QHL1; -.
DR   STRING; 441960.B6QHL1; -.
DR   EnsemblFungi; EEA22856; EEA22856; PMAA_094620.
DR   GeneID; 7026580; -.
DR   KEGG; tmf:PMAA_094620; -.
DR   VEuPathDB; FungiDB:PMAA_094620; -.
DR   HOGENOM; CLU_011918_1_0_1; -.
DR   OrthoDB; 714794at2759; -.
DR   PhylomeDB; B6QHL1; -.
DR   Proteomes; UP000001294; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006571; TLDc_dom.
DR   Pfam; PF07534; TLD; 1.
DR   SMART; SM00584; TLDc; 1.
DR   PROSITE; PS51886; TLDC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..689
FT                   /note="Restriction of telomere capping protein 5"
FT                   /id="PRO_0000408838"
FT   DOMAIN          364..613
FT                   /note="TLDc"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01234"
FT   REGION          154..180
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          328..347
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          519..564
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        154..168
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        542..559
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   689 AA;  75579 MW;  C6B1987C536B9A1E CRC64;
     MGAGQSTGGL ESPSTPEQLS VLLAERFATK CFTPLELTHF KDNFYSRALD QAGFRYWNEK
     ILSDFLSIPD GIYTNEKDGG HDGRLDAGPV IFRMVSYLGA FPFQKTLAPS VLTFDAMVKV
     VVLLTERYGK VLRRGRKDRV KLLFGSLADV GRPVRQEEHN DEGSSSTKTE EAKQSSSHAQ
     GFSVDVSVND EYDEYEDDDD LALAALESLD AIEVFKHDQR IDGAVYEARI SVDTFRRLLM
     LLLAIAPLKP LESVTKYTFN LSSEEQAAVK READTIIASF TEEEIRDGIR YKSFAKTVSI
     SLPHLFDPLT PLFEHLLFSK NLDLSRKQTG ASNASPESHP PIQTPINEEE QPTTIMLPGS
     FESAILTPSL VSHLSFFLPA SSGQNLYRSD IRLHPVFSTV AHGESLTSFQ HNVFTWQAPS
     ILIVQGAAPG SSGTPDELIT LGAYIPQPWK PSSSSWETSQ SLNDKSRLPY LFQIHPKHSV
     LPGNPSLLST REQSSATTPT VYFSTTTGIA IGCEIPASAQ QQRTHYGPGV PSPREHLQHH
     RQSSGGNSIH KQQQQGPIPH GAGSLIIDSG LETAQLHISY LTGSTGVFTR AVPPILPTTT
     HIDIYNLEIW GIIEPDPLIA AVGGDTISRD AISQQRAAWQ FDAREAERRK CINVKLGSGT
     DSEYQNARAL LEMAGIIGDQ AHQRSGGSV