ID   RTC5_TALSN              Reviewed;         686 AA.
AC   B8MJJ8;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   25-MAY-2022, entry version 46.
DE   RecName: Full=Restriction of telomere capping protein 5;
GN   Name=rtc5; ORFNames=TSTA_046520;
OS   Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL
OS   1006) (Penicillium stipitatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC   Talaromyces sect. Talaromyces.
OX   NCBI_TaxID=441959;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006;
RX   PubMed=25676766; DOI=10.1128/genomea.01559-14;
RA   Nierman W.C., Fedorova-Abrams N.D., Andrianopoulos A.;
RT   "Genome sequence of the AIDS-associated pathogen Penicillium marneffei
RT   (ATCC18224) and its near taxonomic relative Talaromyces stipitatus
RT   (ATCC10500).";
RL   Genome Announc. 3:E0155914-E0155914(2015).
CC   -!- FUNCTION: May be involved in a process influencing telomere capping.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RTC5 family. {ECO:0000305}.
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DR   EMBL; EQ962657; EED15198.1; -; Genomic_DNA.
DR   RefSeq; XP_002485151.1; XM_002485106.1.
DR   AlphaFoldDB; B8MJJ8; -.
DR   SMR; B8MJJ8; -.
DR   STRING; 441959.B8MJJ8; -.
DR   EnsemblFungi; EED15198; EED15198; TSTA_046520.
DR   GeneID; 8099563; -.
DR   VEuPathDB; FungiDB:TSTA_046520; -.
DR   eggNOG; ENOG502QV3R; Eukaryota.
DR   HOGENOM; CLU_011918_1_0_1; -.
DR   InParanoid; B8MJJ8; -.
DR   OMA; SHHVLTW; -.
DR   OrthoDB; 714794at2759; -.
DR   PhylomeDB; B8MJJ8; -.
DR   Proteomes; UP000001745; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006571; TLDc_dom.
DR   Pfam; PF07534; TLD; 1.
DR   SMART; SM00584; TLDc; 1.
DR   PROSITE; PS51886; TLDC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..686
FT                   /note="Restriction of telomere capping protein 5"
FT                   /id="PRO_0000408846"
FT   DOMAIN          366..610
FT                   /note="TLDc"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01234"
FT   REGION          155..198
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          326..355
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          522..559
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        155..189
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        522..554
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   686 AA;  75244 MW;  16CFF3B37A15142C CRC64;
     MGASQSTSGI EGASSPEQLS VLLAERFATK CFTPLELTHF KDNFYSRALD QAGFRYWNEK
     ILSDFLSVPD GIYTNEKDGG HDGRLDAGPV VFRMVSYLGA FPFQKTLAPS VLTFDSMVKV
     VVLLTERYGK VLRRGRKDRV KLLFGSLADV GRSLEQDTKK QNDSAESASK SEDSKQSSHV
     HGFSVDEPTN DDYEEHEDDD DLALAALESL DAIEVFKHDQ QIDRAVCEAR ISIDTFRRLL
     MLLLAIAPLR PLESVNKYTF NLSSEEQAAV KREADTIIAS FTEEEIRDGI GYKTFAKTVT
     LSLPHLFDPL TPLFEHLLFS ENLDLSRKQT GQSEPSPESP PSEAPTDANI DEKPTTIMLP
     GSFESAILTP SMVSHLSFFL PASSGQNLYR SDIRLHPVFS TVAHGESLTS FQHNVFTWQA
     PSLLIVQGAL PGSSGSPDEL ITLGAYIPQP WKPSSSSSYE SPQNLNNRSR LPYLFQLHPK
     HSVLPGNSSL LQTKEQPSTT PIVYFSTTTG IAIGCEVPAS AQQHRTSYGP GVPSPHQQPH
     RRQSSTNHKQ QQGPLPHGAG SLIIDAALET AQLHISYLAA HTGVFTPAVP PTLPTITHID
     IYNLEIWGII EPPSLSLLPD SAGIAKDAIS RQREAWQFDA REAERRKGIN VKLGSGNDSN
     YQNAKALLEM AGIIGDQAQQ RSGGSV