ID   RTC5_UNCRE              Reviewed;         660 AA.
AC   C4JHR8;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   07-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 38.
DE   RecName: Full=Restriction of telomere capping protein 5;
GN   Name=RTC5; ORFNames=UREG_02754;
OS   Uncinocarpus reesii (strain UAMH 1704).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Uncinocarpus.
OX   NCBI_TaxID=336963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH 1704;
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA   Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA   McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA   Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA   Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT   and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
CC   -!- FUNCTION: May be involved in a process influencing telomere capping.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RTC5 family. {ECO:0000305}.
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DR   EMBL; CH476615; EEP77905.1; -; Genomic_DNA.
DR   RefSeq; XP_002543238.1; XM_002543192.1.
DR   AlphaFoldDB; C4JHR8; -.
DR   SMR; C4JHR8; -.
DR   STRING; 336963.C4JHR8; -.
DR   EnsemblFungi; EEP77905; EEP77905; UREG_02754.
DR   GeneID; 8437541; -.
DR   KEGG; ure:UREG_02754; -.
DR   VEuPathDB; FungiDB:UREG_02754; -.
DR   eggNOG; ENOG502QV3R; Eukaryota.
DR   HOGENOM; CLU_011918_1_0_1; -.
DR   InParanoid; C4JHR8; -.
DR   OrthoDB; 714794at2759; -.
DR   Proteomes; UP000002058; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR013902; DUF1773.
DR   InterPro; IPR006571; TLDc_dom.
DR   Pfam; PF08593; DUF1773; 1.
DR   Pfam; PF07534; TLD; 1.
DR   SMART; SM00584; TLDc; 1.
DR   PROSITE; PS51886; TLDC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..660
FT                   /note="Restriction of telomere capping protein 5"
FT                   /id="PRO_0000408848"
FT   DOMAIN          359..587
FT                   /note="TLDc"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01234"
FT   REGION          153..199
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        166..187
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   660 AA;  72109 MW;  B6DCDA1CAD67E457 CRC64;
     MGAGQSTTTT EGRSSPEEMS HLLAQRFASK CFTPLELTHL EDNFNSQALD EHGLRYWNEE
     ILSRFLGIPD GAGEKASPQT DATLDAGPVL FRMVSYLGAF PFHNTLAPSV LTYDAIVKVI
     VLLTERYGRV LKRGRKDRMK LLFGSLADVG RTQTEKQRET SQVDTKMSSD EAYSTDGASS
     NITGFSIDAP ANDGEEEDDD DDLALAALES LDAIEVFKHD QRLDRSVYKA RISVSTFRRL
     LALLLVIAPL HPMGRRQMIQ TDAESIDAVQ PSWIASCSLG DEANGDGHYL SDFSRVITTS
     LPFLFDPLTP LFEHFLFSKN LDLSKRKDSH QSHEESNSPS PPPSPHLECV FLPGHFETNI
     LNSAILSHLS FFLSTSYPIP NLFRNQTRLH PVFSSDFHGE SLTAFSHHVL TWHAPSLLLL
     KGVTGSSSSK QETVLAGAYL PEPWKRSTSP LSTPMSDFLD TSRFPCLFQL LPTHTVLQAA
     PAFKSLKSNM PVVSFSTNSG IAVGCMIPPS SRTSLNNELQ PRPSGGGSLI IDPALENATF
     YVSDGLHGDG VFLPPGLSPS SSLSLSASAT SSTMSISIHS IEVWGVVPTP AELDANLDPN
     SPKDAISMQK AMWDFEAREA ERRKTIHLNV GGGDSEAQTG RALLEMAGII GDSQYSPRRR