ID   RTC5_VANPO              Reviewed;         562 AA.
AC   A7TNS4;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 44.
DE   RecName: Full=Restriction of telomere capping protein 5;
GN   Name=RTC5; ORFNames=Kpol_1016p7;
OS   Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS   2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX   NCBI_TaxID=436907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL
RC   Y-8283 / UCD 57-17;
RX   PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA   Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT   "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT   species descended from a whole-genome duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC   -!- FUNCTION: May be involved in a process influencing telomere capping.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RTC5 family. {ECO:0000305}.
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DR   EMBL; DS480434; EDO16067.1; -; Genomic_DNA.
DR   RefSeq; XP_001643925.1; XM_001643875.1.
DR   AlphaFoldDB; A7TNS4; -.
DR   STRING; 436907.A7TNS4; -.
DR   PRIDE; A7TNS4; -.
DR   EnsemblFungi; EDO16067; EDO16067; Kpol_1016p7.
DR   GeneID; 5544212; -.
DR   KEGG; vpo:Kpol_1016p7; -.
DR   eggNOG; ENOG502QV3R; Eukaryota.
DR   HOGENOM; CLU_011918_1_0_1; -.
DR   InParanoid; A7TNS4; -.
DR   OMA; SHHVLTW; -.
DR   OrthoDB; 714794at2759; -.
DR   PhylomeDB; A7TNS4; -.
DR   Proteomes; UP000000267; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006571; TLDc_dom.
DR   Pfam; PF07534; TLD; 1.
DR   SMART; SM00584; TLDc; 1.
DR   PROSITE; PS51886; TLDC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..562
FT                   /note="Restriction of telomere capping protein 5"
FT                   /id="PRO_0000408849"
FT   DOMAIN          283..509
FT                   /note="TLDc"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01234"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   562 AA;  64041 MW;  265DA0791FAC79DA CRC64;
     MGQTPSVESQ ESKETKNEMP ELKSREDILD FFNNRSLSIL LPMEIECFKS RLGDKDLSDP
     LTKDEFNTLL RIADSNSQLQ ILLWNFFLKI SAFPFLSNRS ESMTGFGILK GIILLTRERI
     KKYLGWSNAK LIKLIFIGLT SQEKVGVKTE ASVFKIQHVL DTLDGIDLAS STVKDTDMLS
     FITWLLLLSV HCPTSNCKLN EKSLYDKWKD YEIVASSMVR SMNKKITTTG KGIGISYSDF
     SHTIVAVSKN VMSPLENIVE HMLYKQDDLL EFPCLDTFLK ETKLMTYPLV AQLCTVLPNE
     IVMSQLQKLY VGRESGYSMR SLQSKVFNWK AATILLVSGT RIVDDIEYSE NKNPRYKRFL
     EEYPKLKDED QEMDDCHNLK KKVTFAVYID EPWRVTNKNY FGEKRTSIIE LSPRQDKFNS
     LKVGSVYFNT IGGGIGIGNN QPVTKLNSVR YAPGNVSLTL DNTLEFGVFR HTGYGGTIGP
     SELLKKNNEE NKAFEIRFLI RDVEVWGCGG EKELEEQLRE WKWEEAEAKR RQEINLKTMG
     EDRALLEMAG IIGQHGQSGG SI