ID   RTF2_CHICK              Reviewed;         306 AA.
AC   Q5ZJN1;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Replication termination factor 2 {ECO:0000305};
DE            Short=RTF2;
DE   AltName: Full=Protein RTF2 homolog;
DE   AltName: Full=Replication termination factor 2 domain-containing protein 1;
GN   Name=RTF2; Synonyms=RTFDC1; ORFNames=RCJMB04_16p11;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Replication termination factor which is a component of the
CC       elongating replisome. Interacts with nascent DNA.
CC       {ECO:0000250|UniProtKB:Q9BY42}.
CC   -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000250|UniProtKB:Q9BY42}.
CC       Note=Localizes at the replication fork. {ECO:0000250|UniProtKB:Q9BY42}.
CC   -!- SIMILARITY: Belongs to the rtf2 family. {ECO:0000305}.
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DR   EMBL; AJ720403; CAG32062.1; -; mRNA.
DR   AlphaFoldDB; Q5ZJN1; -.
DR   STRING; 9031.ENSGALP00000012478; -.
DR   PaxDb; Q5ZJN1; -.
DR   VEuPathDB; HostDB:geneid_419329; -.
DR   eggNOG; KOG3113; Eukaryota.
DR   HOGENOM; CLU_048955_1_0_1; -.
DR   InParanoid; Q5ZJN1; -.
DR   OrthoDB; 1385322at2759; -.
DR   PhylomeDB; Q5ZJN1; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0005657; C:replication fork; ISS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0072711; P:cellular response to hydroxyurea; ISS:UniProtKB.
DR   GO; GO:1902979; P:mitotic DNA replication termination; IEA:InterPro.
DR   GO; GO:0097752; P:regulation of DNA stability; ISS:UniProtKB.
DR   CDD; cd16653; RING-like_Rtf2; 1.
DR   InterPro; IPR006735; Rtf2.
DR   InterPro; IPR027799; Rtf2_RING-finger.
DR   PANTHER; PTHR12775; PTHR12775; 1.
PE   2: Evidence at transcript level;
KW   Chromosome; Phosphoprotein; Reference proteome.
FT   CHAIN           1..306
FT                   /note="Replication termination factor 2"
FT                   /id="PRO_0000327238"
FT   REGION          193..265
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        205..230
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        246..265
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   306 AA;  34222 MW;  E2FF99180363272D CRC64;
     MGCDGGTIPK RHELVKGPRK AVKVDKTAEL VARWYYCTLS QEKLCRPIVA CELGRLYNKD
     AVIEFLLDKS ADKTPMEAAS HIKSLKNVTE LNLADNPAWS GDKESKKGDT YDDIQSARFI
     CPVVGLEMNG RHRFCFLRNC GCVFSERALK EIKTEVCHKC GVPFQEEDVI ILNGNKEDVE
     VLKKRMEDRR LKSKLEKKSK KCKSAESAAQ QVTTEDSPGP SKVKNSKDCI ASSSGEKRHI
     IFTKSSDDRS SSVPGKVNKA STATKRSIAD TATRNLRHTN LFTTHSSAKR PKEECSNWVT
     HTAYCF