RTFL3_ORYSJ
ID RTFL3_ORYSJ Reviewed; 124 AA.
AC A0A5S6RB44; Q0JFM3; Q5JM96;
DT 02-JUN-2021, integrated into UniProtKB/Swiss-Prot.
DT 26-FEB-2020, sequence version 1.
DT 03-AUG-2022, entry version 8.
DE RecName: Full=Small polypeptide ROTUNDIFOLIA LIKE 3 {ECO:0000303|PubMed:25701405};
DE Short=OsRTFL3 {ECO:0000303|PubMed:25701405};
DE Short=Small polypeptide ROT-FOUR-LIKE 3 {ECO:0000303|PubMed:25701405};
GN Name=RTFL3 {ECO:0000303|PubMed:25701405};
GN OrderedLocusNames=Os01g0972300 {ECO:0000312|EMBL:BAF07455.2};
GN ORFNames=OsJ_04932 {ECO:0000312|EMBL:EEE56091.1},
GN OSNPB_010972300 {ECO:0000312|EMBL:BAS76437.1},
GN P0518C01.28 {ECO:0000312|EMBL:BAD87367.1},
GN P0698H10.2 {ECO:0000312|EMBL:BAD87411.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447438; DOI=10.1038/nature01184;
RA Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.,
RA Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M.,
RA Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T.,
RA Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S.,
RA Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H.,
RA Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y.,
RA Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S.,
RA Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y.,
RA Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S.,
RA Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H.,
RA Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.;
RT "The genome sequence and structure of rice chromosome 1.";
RL Nature 420:312-316(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP GENE FAMILY.
RX PubMed=15125775; DOI=10.1111/j.1365-313x.2004.02078.x;
RA Narita N.N., Moore S., Horiguchi G., Kubo M., Demura T., Fukuda H.,
RA Goodrich J., Tsukaya H.;
RT "Overexpression of a novel small peptide ROTUNDIFOLIA4 decreases cell
RT proliferation and alters leaf shape in Arabidopsis thaliana.";
RL Plant J. 38:699-713(2004).
RN [7]
RP FUNCTION, REVIEW, GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Taichung 65;
RX PubMed=25701405; DOI=10.1007/s10265-015-0703-1;
RA Guo P., Yoshimura A., Ishikawa N., Yamaguchi T., Guo Y., Tsukaya H.;
RT "Comparative analysis of the RTFL peptide family on the control of plant
RT organogenesis.";
RL J. Plant Res. 128:497-510(2015).
CC -!- FUNCTION: Small polypeptide acting as a regulatory molecule which
CC coordinates cellular responses required for differentiation, growth and
CC development, probably by restricting polar cell proliferation in
CC lateral organs (e.g. leaves and petioles).
CC {ECO:0000269|PubMed:25701405}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q7XXN8};
CC Single-pass membrane protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the DVL/RTFL small polypeptides family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP003277; BAD87367.1; -; Genomic_DNA.
DR EMBL; AP003298; BAD87411.1; -; Genomic_DNA.
DR EMBL; AP008207; BAF07455.2; -; Genomic_DNA.
DR EMBL; AP014957; BAS76437.1; -; Genomic_DNA.
DR EMBL; CM000138; EEE56091.1; -; Genomic_DNA.
DR RefSeq; XP_015645260.1; XM_015789774.1.
DR AlphaFoldDB; A0A5S6RB44; -.
DR SMR; A0A5S6RB44; -.
DR STRING; 4530.OS01T0972300-01; -.
DR EnsemblPlants; Os01t0972300-01; Os01t0972300-01; Os01g0972300.
DR GeneID; 4326395; -.
DR Gramene; Os01t0972300-01; Os01t0972300-01; Os01g0972300.
DR KEGG; osa:4326395; -.
DR eggNOG; ENOG502S3XH; Eukaryota.
DR HOGENOM; CLU_150897_0_0_1; -.
DR OMA; PPQFYFD; -.
DR OrthoDB; 1634400at2759; -.
DR Proteomes; UP000000763; Chromosome 1.
DR Proteomes; UP000007752; Chromosome 1.
DR Proteomes; UP000059680; Chromosome 1.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008285; P:negative regulation of cell population proliferation; IMP:UniProtKB.
DR GO; GO:0042127; P:regulation of cell population proliferation; IMP:UniProtKB.
DR GO; GO:0048367; P:shoot system development; IMP:UniProtKB.
DR InterPro; IPR012552; DVL.
DR Pfam; PF08137; DVL; 1.
PE 3: Inferred from homology;
KW Cell membrane; Developmental protein; Glycoprotein; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..124
FT /note="Small polypeptide ROTUNDIFOLIA LIKE 3"
FT /id="PRO_0000452795"
FT TRANSMEM 59..75
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 60..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 92..124
FT /note="Required for DVL/RTFL small polypeptide activity"
FT /evidence="ECO:0000250|UniProtKB:Q7XXN8"
FT COMPBIAS 67..95
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 35
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 38
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 88
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ SEQUENCE 124 AA; 13743 MW; 535F4C48EB96B051 CRC64;
MEDERWKLSS SKGRSKSGRS CSSSSNYYYH SSDFNSSNAT TLSRSYSASV TASRHATTAW
SAAGAGGGGA SSSSSSQHQH QQQQQQSNNS QRLSKKCVEA VKEHRARFYI VRRCVSMLVC
WRDY
